Mouse Model News and Research

RSS

New studies examine links between fatty liver disease and mitochondrial dysfunction

Researchers at Northeast Ohio Medical University studied the lifespan of mitochondrial proteins in a mouse model of fatty liver disease. Comparing the amount of protein between healthy mice and a mouse model of nonalcoholic fatty liver disease gave them an estimate of each protein's half-life.

17 Sep 2018

Investigators pinpoint exact stage of retinoblastoma development in children

Investigators at Children's Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses.

14 Sep 2018

How 'bad' bacteria gain an upper hand in the human gut

A study has revealed that the bacterium C. difficile gains a competitive advantage over protective bacteria in the human gut by producing para-cresol.

11 Sep 2018

Gene involved in circadian rhythms can be potential target for glioblastoma treatment

Scientists with the Virginia Tech Carilion Research Institute say a gene involved in the body's circadian rhythms is a potential target for therapies to help patients with a deadly form of brain cancer known as glioblastoma.

11 Sep 2018

New study aims to understand why skin grafts have high rate of rejection

When it comes to transplant rejection, some organs are far trickier than others. Some transplantable organs, such as the liver, are readily accepted by the recipient's immune system, rarely triggering an immune response and rejection

7 Sep 2018

Researchers program open wound cells to turn into healthy skin

Researchers at the Salk Institute have found a way to convert the cells in open wounds into new skin cells, potentially eliminating the need for plastic surgery in the treatment of large wounds.

6 Sep 2018

Tipping the scales to initiate tumorigenesis in the colon

The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. c-MYC is a transcription factor that controls the activity of large numbers of genes involved in cell division, and its overexpression leads to excessive cell proliferation.

5 Sep 2018

Scientists receive $2.5 million grant to combat South American-borne deadly disease

A George Mason University researcher is heading a scientific team that has received a sizable Department of Defense grant to combat the threat of a South American-borne disease that can cause long-term neurological problems and even death.

5 Sep 2018

Mouse models may not completely reflect severity of gonorrhea infection

There is an urgent need to develop a vaccine to prevent gonorrhea infection due to rapidly increasing incidence and growing antibiotic resistance.

4 Sep 2018

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Stanford University School of Medicine researchers have demonstrated that gene therapy can be effective without causing a dangerous side effect common to all gene therapy: an autoimmune reaction to the normal protein, which the patient's immune system is encountering for the first time.

4 Sep 2018

Neutrophil nanosponges provide hope for rheumatoid arthritis

Scientists in San Diego have developed nanosponges coated in neutrophil membranes that can prevent rheumatoid arthritis.

3 Sep 2018

Cryptosporidiosis worsened by commonly used probiotic

Researchers have found that infection with the intestinal parasite Cryptosporidium parvum is worsened in mice that have been administered a probiotic.

31 Aug 2018

Modified T lymphocytes prevent nerve cell damage in encephalitis

Scientists have found a way to prevent neuron death in Rasmussen’s encephalitis, by exploiting T lymphocytes in the immune system.

30 Aug 2018

HKBU chemists discover metal-based inhibitor to treat triple-negative breast cancer

Chemists at Hong Kong Baptist University have discovered the use of a metal compound that inhibits the enzyme closely associated with triple-negative breast cancer, one of the most difficult forms of breast cancer to treat.

30 Aug 2018

Soluble versions of immune cell protein could help treat Alzheimer's disease, study reveals

Researchers at the University of Florida have discovered that a modified version of an important immune cell protein could be used to treat Alzheimer's disease.

29 Aug 2018

Scientists discover potential treatment for Alzheimer’s disease

Scientists discovered a modified version of an immune cell receptor called a toll-like receptor that could be used as a treatment for Alzheimer’s disease.

29 Aug 2018

Lack of protein in father's diet can impact long-term health of his offspring

New research has shown that a lack of protein in a father's diet affects sperm quality which can have a direct impact on the long-term health of their offspring.

29 Aug 2018

New technique for mapping flow of biomolecules in tumor microenvironment

Cancer researchers struggle to identify tumor cells that are interspersed within nonmalignant tissues because tumor cells exploit the tissue environment and monopolize available resources to continue growing.

29 Aug 2018

Mice study reveals brain-heart biomarker for epilepsy after malaria

Animals that develop epilepsy after an infection can be identified as early as three months prior to their first seizure by measuring interactions between the brain and the heart.

From Society for Neuroscience 28 Aug 2018

Researchers reveal an unlikely protector against growth of metastatic breast cancer

At the time of initial diagnosis, most patients with breast cancer show no signs that their cancer has spread elsewhere in the body. Yet, up to 30 percent of patients will ultimately experience metastasis, with breast cancer taking root and growing at other sites in the body, sometimes months, years or even decades later.

27 Aug 2018

Mouse Model News and Research

New studies examine links between fatty liver disease and mitochondrial dysfunction

Investigators pinpoint exact stage of retinoblastoma development in children

How 'bad' bacteria gain an upper hand in the human gut

Gene involved in circadian rhythms can be potential target for glioblastoma treatment

New study aims to understand why skin grafts have high rate of rejection

Researchers program open wound cells to turn into healthy skin

Tipping the scales to initiate tumorigenesis in the colon

Scientists receive $2.5 million grant to combat South American-borne deadly disease

Mouse models may not completely reflect severity of gonorrhea infection

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Neutrophil nanosponges provide hope for rheumatoid arthritis

Cryptosporidiosis worsened by commonly used probiotic

Modified T lymphocytes prevent nerve cell damage in encephalitis

HKBU chemists discover metal-based inhibitor to treat triple-negative breast cancer

Soluble versions of immune cell protein could help treat Alzheimer's disease, study reveals

Scientists discover potential treatment for Alzheimer’s disease

Lack of protein in father's diet can impact long-term health of his offspring

New technique for mapping flow of biomolecules in tumor microenvironment

Mice study reveals brain-heart biomarker for epilepsy after malaria

Researchers reveal an unlikely protector against growth of metastatic breast cancer

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News