Mouse Model News and Research

RSS

Researchers identify new regulator in breast cancer cells

Triple-negative breast cancer is a particularly aggressive form of breast cancer. Here, important receptors are missing, which often serve as targets for treatments.

6 Aug 2018

Research uncovers new approach for expanding stem cells from umbilical cord blood

Researchers from the Stowers Institute for Medical Research and collaborators have identified a way to expand blood-forming, adult stem cells from human umbilical cord blood.

3 Aug 2018

Study provides new insights into how asthma develops and progresses

Of the more than 24 million people in the U.S. who have asthma, 10 percent have severe asthma - a form of the disease that does not respond to treatment.

3 Aug 2018

Alcohol increases mortality in young mice infected with tuberculosis-causing bacterium

Alcohol increases the mortality of young but not old mice infected with the tuberculosis-causing bacterium Mycobacterium tuberculosis, and this effect is mediated by the production of a protein called interferon-alpha.

3 Aug 2018

Tumor suppressor gene PTEN may be potential Achilles heel for breast cancer cells

In an article published July 17, 2018 by Nature Communications, a highly collaborative team of researchers at the Medical University of South Carolina and Ohio State University report that normal breast cells can prevent successful radiation treatment of breast cancer due to dysregulation between tumor suppressors and oncogenes.

2 Aug 2018

Breakthrough in stem cell research could lead to cure for cystic fibrosis

Researchers have successfully proved that gene therapy can be used to convert adult stem cells into functioning lung cells for the treatment of cystic fibrosis

2 Aug 2018

Researchers find possible active substance that may cure hepatitis E

An international team of researchers has now found a possible active substance against the virus in the naturally occurring substance silvestrol.

1 Aug 2018

Glaucoma Research Foundation-funded research makes breakthrough in treatment of glaucoma

Glaucoma Research Foundation, a national non-profit organization dedicated to finding a cure for glaucoma, today announced a team of neuroscience researchers, led by Adriana Di Polo, PhD, at University of Montreal, have made a major breakthrough in the treatment of glaucoma.

31 Jul 2018

Gene linked to hair loss could be exploited to improve cancer immunotherapy

A gene that's associated with an autoimmune form of hair loss could be exploited to improve cancer immunotherapy, suggests a new mouse study by Columbia University Irving Medical Center (CUIMC) researchers.

31 Jul 2018

New improved mouse model could revolutionize bone metastasis research

Researchers at Tokyo Institute of Technology propose an improved mouse model that could revolutionize bone metastasis research. Their method, which involves injecting cancer cells via the so-called caudal artery in the mouse tail, overcomes many limitations of traditional mouse models.

30 Jul 2018

Researchers discover how breast cells prevent cancer invasion

Researchers have shown that the cell layer surrounding breast milk ducts reaches out and engulfs cancerous cells to stop their spread.

30 Jul 2018

Scientists use new drug discovery system to target Huntington’s Disease

Scientists have used a new drug discovery system to specifically target phosphatases in Huntington's, which were previously thought to be undruggable.

27 Jul 2018

Scientists use new drug discovery system to target Huntington’s Disease

Scientists have used a new drug discovery system to specifically target phosphatases in Huntington's, which were previously thought to be undruggable.

27 Jul 2018

New drug discovery system allows scientists to target ‘undruggable’ enzymes

A new drug discovery system allows scientists to specifically target members of an important family of enzymes, called phosphatases, which were previously considered mostly "undruggable".

27 Jul 2018

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

An international team of scientists, including researchers from Baylor College of Medicine, has discovered mutations of gene IRF2BPL that are associated with a previously undiagnosed neurological disorder in seven unrelated individuals.

27 Jul 2018

Research findings may offer new path to treat or prevent neurodegenerative diseases

Aging vessels connecting the brain and the immune system play critical roles in both Alzheimer's disease and the decline in cognitive ability that comes with time, new research reveals.

26 Jul 2018

New mouse model shows great promise for Rett syndrome research

In an article released today from Jeannie T. Lee, MD PhD of Massachusetts General Hospital, there is hope on the horizon for future research specific to Rett syndrome, a rare childhood neurodevelopmental disorder.

26 Jul 2018

Scientists uncover new strategy to kill tumors without harming healthy cells

Scientists at Scripps Research have uncovered a new strategy to kill tumors, including some triple-negative breast cancers, without harming healthy cells, a discovery that could lead to more ways to treat tumors while reducing side effects.

26 Jul 2018

Ciprofloxacin may disrupt normal functions of connective tissue

The use of ciprofloxacin and other antibiotics of the class of fluoroquinolones may be associated with disruption of the normal functions of connective tissue, including tendon rupture, tendonitis and retinal detachment

26 Jul 2018

New target for pneumonia seems to restore tight barriers and fluid clearance in the lungs

Severe pneumonia causes a buildup of fluid in the lungs that makes the basics of breathing and getting oxygen out to the body difficult to impossible.

25 Jul 2018

Mouse Model News and Research

Researchers identify new regulator in breast cancer cells

Research uncovers new approach for expanding stem cells from umbilical cord blood

Study provides new insights into how asthma develops and progresses

Alcohol increases mortality in young mice infected with tuberculosis-causing bacterium

Tumor suppressor gene PTEN may be potential Achilles heel for breast cancer cells

Breakthrough in stem cell research could lead to cure for cystic fibrosis

Researchers find possible active substance that may cure hepatitis E

Glaucoma Research Foundation-funded research makes breakthrough in treatment of glaucoma

Gene linked to hair loss could be exploited to improve cancer immunotherapy

New improved mouse model could revolutionize bone metastasis research

Researchers discover how breast cells prevent cancer invasion

Scientists use new drug discovery system to target Huntington’s Disease

Scientists use new drug discovery system to target Huntington’s Disease

New drug discovery system allows scientists to target ‘undruggable’ enzymes

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

Research findings may offer new path to treat or prevent neurodegenerative diseases

New mouse model shows great promise for Rett syndrome research

Scientists uncover new strategy to kill tumors without harming healthy cells

Ciprofloxacin may disrupt normal functions of connective tissue

New target for pneumonia seems to restore tight barriers and fluid clearance in the lungs

Industry Focus eBook - Cell biology (5th edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News