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New screening platform can be used to discover more effective drugs for type 1 diabetes

With nearly 2 million Americans battling type 1 diabetes, it is no surprise that clinical therapies for the disease are constantly evolving and improving.

16 Dec 2020

Report highlights research challenges and opportunities to advance cancer care

A new report finds that despite progress in the decline of cancer mortality, there are still critical gaps including the need to develop better tools and explore research opportunities that would lead to limiting cancer as a major health concern.

16 Dec 2020

SARS-CoV-2 unique deletion variants found in clinical specimens

While participating in the SPHERES Consortium project, US researchers sequenced 2,726 clinical patient specimens gathered in March 2020 and identified eight unique ORF7a deletion variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Their results are currently available on the bioRxiv* preprint server.

15 Dec 2020

Research could lead to potential new treatments for mutant RAS-driven cancers

Scientists have dedicated huge amounts of time and resources to better understanding the causes and mechanisms of cancer growth.

15 Dec 2020

SIMON – The Machine Learning Platform Paving the Future of Vaccine Development

A machine learning algorithm developed by the Oxford Vaccine Group promises more effective vaccine development for several diseases, including COVID-19.

15 Dec 2020

New combination therapy has potential to treat aggressive cancers with common mutations

Scientists have long known that therapies that target the cancer-driving MAPK pathway are only effective in a handful of cancers with specific mutations in a cancer gene called BRAF, and these cancers that initially respond to the therapy often end up developing resistance to the treatment, resulting in relapse for many patients.

14 Dec 2020

Moffitt Cancer Center finds a way for researchers and patients to engage with each other

Behind every new cancer treatment and scientific breakthrough is a research team. However, because they spend most of their time in their labs, basic science researchers rarely get to meet the patients who benefit most from their work.

14 Dec 2020

Takeda brings innovative pipeline portfolio to patients for sustained revenue growth

As part of its Wave 1 Pipeline Market Opportunity Call, Takeda Pharmaceutical Company Limited provided an update on its pipeline portfolio, which has the potential to contribute significantly to revenue growth for the company over the next decade.

From Takeda 10 Dec 2020

Tomatoes could become a new, natural source of Parkinson's disease drug

Scientists have produced a tomato enriched in the Parkinson's disease drug L-DOPA in what could become a new, affordable source of one of the world's essential medicines.

9 Dec 2020

Study findings can guide personalized breast cancer therapies based on melatonin

A Brazilian study published in the Journal of Pineal Research describes a group of genes potentially regulated by the hormone melatonin in some types of cancer, especially breast cancer.

8 Dec 2020

Study highlights rising infant health inequality in the U.S.

After several decades of improvement, inequality in infant health is once again on the rise in the United States, a pair of Brown University researchers has found.

8 Dec 2020

Study highlights previously unknown mechanisms involved in myeloma resistance

A group of researchers led by Maximillian Merz, MD, Assistant Professor of Oncology with the Myeloma team at Roswell Park Comprehensive Cancer Center, conducted the first prospective clinical trial investigating spatial heterogeneity in patients with either relapsed/refractory or newly diagnosed multiple myeloma.

7 Dec 2020

Researchers shed light on the role of antibodies and immune cells in protection against COVID-19

Since the novel coronavirus emerged at the end of last year, scientists around the world -- including Beth Israel Deaconess Medical Center (BIDMC) immunologist Dan Barouch, MD, PhD -- have been developing vaccines to protect against COVID-19 and to put an end to the global pandemic.

5 Dec 2020

A new potential therapy for Alzheimer's disease

A new potential therapeutic target for Alzheimer’s disease has been discovered by US researchers based at Case Western Reserve University.

4 Dec 2020

Researchers identify pathogenic organism that can transmit diseases in Bolson tortoise

The Bolson tortoise (Bolson Gopherus flavomarginatus) is the largest land reptile in North America. It lives mainly in dry areas, in particular, in the Chihuahua desert in northern Mexico. In recent decades, its numbers have fallen by 50%, driving the International Union for Conservation of Nature to include it on its red list and it has been classified as endangered.

4 Dec 2020

Study shows metformin can significantly reduce COVID-19 death risks in women

University of Minnesota Medical School and UnitedHealth Group researchers found that metformin was associated with significantly reduced COVID-19 death risks in women in one of the world's largest observational studies of COVID-19 patients.

3 Dec 2020

Surprising discovery reveals new target for aggressive lung adenocarcinoma

Targeted therapies are currently available for about one-third of people with lung adenocarcinoma, the most common kind of lung cancer.

2 Dec 2020

Study: Tumors with high TMB tend to respond better to immune checkpoint inhibitors

Treatments that harness the immune system to fight cancer have greatly improved outcomes for some people with cancer. Scientists are learning more about why some people respond much better than others to these drugs.

2 Dec 2020

Cancer cells exhibit metabolic changes that make them vulnerable to ferroptosis

If there is a silver lining in cancer's chaotic biology, it's that the same traits that give cancer cells a growth advantage often present opportunities for sabotaging them.

2 Dec 2020

Breakthrough in microscopy, endoscopy may soon revolutionize the study of cellular origin of diseases

A breakthrough in microscopy and endoscopy will soon revolutionize the study of the cellular origin of diseases, advancing the field of precision medicine. This is the goal of CRIMSON, a trans-disciplinary and trans-national research project recently funded by European Commission.

2 Dec 2020

Next Generation News and Research

New screening platform can be used to discover more effective drugs for type 1 diabetes

Report highlights research challenges and opportunities to advance cancer care

SARS-CoV-2 unique deletion variants found in clinical specimens

Research could lead to potential new treatments for mutant RAS-driven cancers

SIMON – The Machine Learning Platform Paving the Future of Vaccine Development

New combination therapy has potential to treat aggressive cancers with common mutations

Moffitt Cancer Center finds a way for researchers and patients to engage with each other

Takeda brings innovative pipeline portfolio to patients for sustained revenue growth

Tomatoes could become a new, natural source of Parkinson's disease drug

Study findings can guide personalized breast cancer therapies based on melatonin

Study highlights rising infant health inequality in the U.S.

Study highlights previously unknown mechanisms involved in myeloma resistance

Researchers shed light on the role of antibodies and immune cells in protection against COVID-19

A new potential therapy for Alzheimer's disease

Researchers identify pathogenic organism that can transmit diseases in Bolson tortoise

Study shows metformin can significantly reduce COVID-19 death risks in women

Surprising discovery reveals new target for aggressive lung adenocarcinoma

Study: Tumors with high TMB tend to respond better to immune checkpoint inhibitors

Cancer cells exhibit metabolic changes that make them vulnerable to ferroptosis

Breakthrough in microscopy, endoscopy may soon revolutionize the study of cellular origin of diseases

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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