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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

Oral host responses to SARS-CoV-2 predict progression of COVID-19

In a recent study posted to the medRxiv* preprint server, researchers at the University of North Carolina and the National Institutes of Health determined the associations between oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), oral antibodies against SARS-CoV-2, and coronavirus disease 2019 (COVID-19) symptoms.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

Hyperinflammation triggers long COVID headaches

Researchers characterize the immunological and metabolic alterations involved in chronic headache onset during post-acute sequelae of COVID-19.

13 Mar 2023

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including the most common type of head and neck cancer, and elevated levels of white blood cells that produce antibodies within tumors.

13 Mar 2023

Scientists study how maternal SARS-CoV-2 infection during pregnancy affects child’s brain development

Scientists led by the Lieber Institute for Brain Development are studying how a mother's SARS-CoV-2 infection during pregnancy affects the biology of the placenta and the corresponding trajectory of the child's brain development, including the risk for neurodevelopmental disorders such as schizophrenia and autism.

13 Mar 2023

Astrocytes play a key role in motor learning

From steering a car to swinging a tennis racket, we learn to execute all kinds of skilled movements during our lives.

10 Mar 2023

New discoveries made regarding autism onset in mouse models

Although autism is a common neurodevelopmental disorder, the multiple factors behind its onset are still not fully understood.

10 Mar 2023

Newly found protein complex plays a crucial role in messenger RNA stability

Two proteins come together to protect and stabilize RNA as it carries muscle-forming code through the cell. Further understanding this RNA-stabilizing complex may have implications for influencing muscle recovery and disease treatment.

9 Mar 2023

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Researchers identified that individuals with a deficiency of myeloid differentiation primary response 88 (MyD88) and interleukin-1 receptor-associated kinase 4 (IRAK-4) due to an autosomal recessive condition were highly susceptible to developing hypoxemic coronavirus disease 2019 (COVID-19) pneumonia when infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Mar 2023

Connection between mitochondrial metabolite and activation of inflammatory response revealed

A new study shows for the first time a connection between a mitochondrial metabolite and the activation of an inflammatory response.

8 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

New insights into the effects of a hormonal treatment for transgender men, discovered by Cedars-Sinai investigators, could have implications for the treatment of breast cancer.

8 Mar 2023

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type.

8 Mar 2023

Study may provide a new target for treatment of Alzheimer's disease

Reducing the methylation of a key messenger RNA can promote migration of macrophages into the brain and ameliorate symptoms of Alzheimer's disease in a mouse model, according to a new study publishing March 7th in the open access journal PLOS Biology by Rui Zhang of Air Force Medical University in Xian, Shaanxi, China.

7 Mar 2023

RNA News and Research

Further Reading

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Oral host responses to SARS-CoV-2 predict progression of COVID-19

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Hyperinflammation triggers long COVID headaches

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Scientists study how maternal SARS-CoV-2 infection during pregnancy affects child’s brain development

Astrocytes play a key role in motor learning

New discoveries made regarding autism onset in mouse models

Newly found protein complex plays a crucial role in messenger RNA stability

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Connection between mitochondrial metabolite and activation of inflammatory response revealed

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Study may provide a new target for treatment of Alzheimer's disease

New blood test examines biomarkers to help determine a person's risk for anxiety

Decades of substantial U.S. Government investment in mRNA technology paved way for COVID-19 vaccines

Zoo study: SARS-CoV-2 surveillance across all mammal species

BioInfect: Bringing the best brains to the challenge of antimicrobial resistance

Brain development in autistic Individuals differs from people with typical neurodevelopment, study confirms

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