Autoimmunity News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

SARS-CoV-2 mRNA vaccine efficacy reduced in patients with CD20-B-cell depleting treatment history

Researchers from Switzerland recently investigated humoral and cell-mediated immune responses to mRNA-based vaccines in patients undergoing treatment with CD20-B-cell depleting agents for autoimmune diseases, transplantation, or malignancy.

12 Jul 2021

Exposure to beneficial microorganisms is not affected by targeted hygiene or cleaning

The theory that modern society is too clean, leading to defective immune systems in children, should be swept under the carpet, according to a new study by researchers at UCL and the London School of Hygiene & Tropical Medicine.

5 Jul 2021

EULAR Patient Research Partners join in new research project to advance treatment of psoriatic arthritis

Eleven Patient Research Partners (PRPs) from three organizations (EULAR, GRAPPA-EU, and EUROPSO) participate in the new research project HIPPOCRATES, ensuring the patients' perspective is preserved and prioritized in all research activities to maximize the project's impact.

2 Jul 2021

Connective tissue protein promotes immune responses that fight bacterial infections

A connective tissue protein known to support the framework of organs also encourages immune responses that fight bacterial infections, while restraining responses that can be deadly in the condition called sepsis, a new study finds.

28 Jun 2021

UCLA scientists discover how immune cells can be trained to fight potential threats

The body's immune cells naturally fight off viral and bacterial microbes and other invaders, but they can also be reprogrammed or "trained" to respond even more aggressively and potently to such threats, report UCLA scientists who have discovered the fundamental rule underlying this process in a particular class of cells.

24 Jun 2021

Cancer immunotherapy may self-limit its efficacy in fighting tumors, study finds

Cancer immunotherapy involving drugs that inhibit CTLA-4 also activates an unwanted response that may self-limit its efficacy in fighting tumors, according to a new study led by Francesco Marangoni, Ph.D., assistant professor of physiology & biophysics and member of the Institute for Immunology at the University of California, Irvine.

22 Jun 2021

A World First: sequencing polyclonal antibodies using only proteomics

News-Medical speaks to Bin Ma, President of Rapid Novor, about their latest research that sequenced polyclonal antibodies using only proteomics.

From Rapid Novor Inc 21 Jun 2021

Passive smoking and air pollution associated with arthritis risk, poor response to RA treatment

RA is an inflammatory autoimmune disease that causes pain, swelling and stiffness in the joints. It can also cause fatigue, and the underlying inflammation may affect other body systems.

18 Jun 2021

Researchers assess the incidence of dementia or heart failure in people with rheumatoid arthritis

RA is an inflammatory autoimmune disease that causes pain, swelling and stiffness in the joints. It can also cause fatigue, and the underlying inflammation may affect other body systems.

18 Jun 2021

Study shows how epigenetic factors modulate the risk of type 1 diabetes

Genetics plays a major role in determining a person’s risk of developing type 1 diabetes, but environmental and lifestyle factors are also important. In an article recently published in Chinese Medical Journal, a team of researchers explore the interplay of genetic and environmental factors by summarizing the literature on type 1 diabetes and epigenetics—the study of how gene expression patterns can be modified.

18 Jun 2021

Study shows link between breast milk, gut bacteria, and development of the immune system

Many diseases caused by a dysregulated immune system, such as allergies, asthma and autoimmunity, can be traced back to events in the first few months after birth.

17 Jun 2021

UCSF launches new initiative to propel the development of living therapeutics

UC San Francisco is launching a new initiative to propel the development of living therapeutics - a category of treatments broadly defined as human and microbial living cells that are selected, modified, or engineered to treat or cure disease - and bring them quickly to patients.

14 Jun 2021

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

Various viruses and bacteria have long been known to cause autoimmune diseases where there is such a predisposition. This phenomenon also seems to play a major role in SARS-CoV-2, especially in severe courses.

8 Jun 2021

Brain study may lead to new treatments for neuro-immune conditions

The immune system is the brain's best frenemy. It protects the brain from infection and helps injured tissues heal, but it also causes autoimmune diseases and creates inflammation that drives neurodegeneration.

8 Jun 2021

Measuring how patterns of gene expression change in children may help predict T1D progression

Type 1 diabetes (T1D) is an autoimmune disease in which a misdirected immune system gradually destroys healthy pancreatic islet β cells, resulting in a lack of insulin.

7 Jun 2021

NCI grants more than $4.2 million to launch Cancer Epitope Database and Analysis Resource

Researchers are about to welcome a new one-stop shop for crucial information on how the immune system targets cancers.

3 Jun 2021

Are COVID-19-related complications in children explained by abnormal immune responses?

A common theme in reports on COVID-19 around the world has been the large number of children who have not been infected or shown signs of disease. However, though the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes less acute infection in this age group, it is associated with a severe immune-mediated multisystemic illness called multisystem inflammatory syndrome in children (MIS-C).

20 May 2021

Autoimmunity News and Research

Further Reading

SARS-CoV-2 mRNA vaccine efficacy reduced in patients with CD20-B-cell depleting treatment history

Exposure to beneficial microorganisms is not affected by targeted hygiene or cleaning

EULAR Patient Research Partners join in new research project to advance treatment of psoriatic arthritis

Connective tissue protein promotes immune responses that fight bacterial infections

UCLA scientists discover how immune cells can be trained to fight potential threats

Cancer immunotherapy may self-limit its efficacy in fighting tumors, study finds

A World First: sequencing polyclonal antibodies using only proteomics

Passive smoking and air pollution associated with arthritis risk, poor response to RA treatment

Researchers assess the incidence of dementia or heart failure in people with rheumatoid arthritis

Study shows how epigenetic factors modulate the risk of type 1 diabetes

Study shows link between breast milk, gut bacteria, and development of the immune system

UCSF launches new initiative to propel the development of living therapeutics

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

Brain study may lead to new treatments for neuro-immune conditions

Measuring how patterns of gene expression change in children may help predict T1D progression

NCI grants more than $4.2 million to launch Cancer Epitope Database and Analysis Resource

Are COVID-19-related complications in children explained by abnormal immune responses?

DNAM-1 receptor could be used as new molecular target for treating autoimmune diseases

Researchers evaluate diagnostic criteria for anti-NMDA receptor encephalitis in Japanese children

Researchers show SARS-CoV-2 genes can be integrated into the human genome

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