Catalyst News and Research

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Study offers critical clues into longstanding mystery of deep sleep

Healthy sleep is a basic physiologic need. In its absence, a myriad of processes in the body can go terribly awry. Chronic sleep problems have been linked to mental health disorders, cardiovascular disease, type 2 diabetes, and obesity, among other conditions.

28 Apr 2022

Researchers reveal how not-yet-malignant cells “turn on” and become metastatic breast cancer

Mount Sinai researchers have discovered a previously unknown mechanism in which not-yet-malignant cells from early breast cancer tumors travel to other organs and, eventually, "turn on" and become metastatic breast cancer.

26 Apr 2022

Phase I/II trials of new paratyphoid vaccine begin in Oxford

The University of Oxford in collaboration with the University of Maryland School of Medicine has begun recruiting for a Phase I/II trial of a new paratyphoid vaccine in human volunteers in Oxford - with first vaccinations taking place today (Tuesday).

26 Apr 2022

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

Alzheimer's disease is marked by a loss of functional neurons in the brain. But what causes this loss? Through single-cell genome sequencing, researchers at Boston Children's Hospital, Brigham and Women's Hospital, and the Broad Institute show that people with Alzheimer's have an abundance of newly acquired mutations in their neurons -; more than people of the same age without Alzheimer's, and enough to disable genes important to brain function.

20 Apr 2022

CHEST and Three Lakes Foundation collaborate to reduce delays in diagnosing Interstitial Lung Diseases

Three Lakes Foundation and the American College of Chest Physicians recently announced their collaboration on a multiphase educational initiative aiming to reduce the time it takes to diagnose patients with Interstitial Lung Diseases (ILD).

19 Apr 2022

New chemical reaction creates a faster, simpler way of making tertiary amines for medicines

A University of Illinois at Urbana-Champaign research team has discovered a way to produce a special class of molecule that could open the door for new drugs to treat currently untreatable diseases.

15 Apr 2022

$2 million funding to support Friendship Bench program for helping people with mental health issues

Many more people with depression and other mental health issues will be able to get help from the Friendship Bench programme thanks to a $2 million unrestricted funding from the philanthropist MacKenzie Scott.

12 Apr 2022

Insight into the Breast Cancer Landscape with Breast Cancer Now

In this interview, we speak with Dr. Simon Vincent, Director of Research, Support, and Influencing at Breast Cancer Now, about the current landscape of breast cancer.

12 Apr 2022

Imbalances in the intestinal virome may promote inflammatory bowel disease, research shows

Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine?

8 Apr 2022

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

For patients with cancer, the tumor-killing power of chemotherapeutic drugs is a double-edged sword. While many cancer drugs kill tumor cells, they can also harm healthy cells as they travel throughout the bloodstream.

6 Apr 2022

Virtual reality psychological therapy shown to work well for patients with mental health problems

In a landmark development, psychological therapy has been automated in virtual reality. With the user guided by a virtual coach, there is no need for a real-life therapist, meaning the treatment can reach many more patients.

6 Apr 2022

Poorly understood brain region may play a key role in how we experience pain

A new review paper, published in the journal Brain, has shown that a poorly understood region of the brain called the claustrum may play an important role in how we experience pain.

31 Mar 2022

Penn researchers generate functional CAR T cells with enhanced anti-tumor potency in 24 hours

A new approach from Penn Medicine researchers could cut the time it takes to alter patients' immune cells for infusion back into the body to find and attack cancer.

29 Mar 2022

Optical coherence tomography reveals the beating and development of human heart organoids

Researchers have been using organoids -; 3D organ-like, tightly-packed cell cultures -; as models to study organ development, disease and drug discovery with excellent success.

16 Mar 2022

Highly sensitive PCR test for COVID-19 receives FDA emergency use authorization

A new highly sensitive, easy-to-use test for COVID-19 that requires a single swab and 15 minutes has received emergency use authorization (EUA) status from the U.S. Food and Drug Administration (FDA).

16 Mar 2022

Deploying artificial intelligence to prevent delayed and missed care

Medical imaging is one of the most widely used diagnostic tools in health care with providers ordering dozens of imaging studies for their patients every day.

16 Mar 2022

Zentalis contributes $1 million to SU2C Catalyst program for research into targeted cancer therapeutics

Stand Up To Cancer and Zentalis Pharmaceuticals, Inc. today announced that Zentalis will contribute $1 million to the SU2C Catalyst program to support research that investigates the use of certain small molecule inhibitors for treating a variety of cancer types.

15 Mar 2022

ESGO, ENGAGe and AstraZeneca launch the Ovarian Cancer Commitment

Today, the European Society of Gynaecological Oncology, the European Network of Gynaecological Cancer Advocacy Groups and AstraZeneca announce the establishment of the Ovarian Cancer Commitment, a bold coalition focusing on improving the experience and survival of women with ovarian cancer.

14 Mar 2022

Mild SARS-CoV-2 infection leads to tissue damage and shrinkage in brain areas related to smell

Researchers from the University of Oxford have used data from UK Biobank participants to look at changes to the brain on average 4.5 months after mild SARS-CoV-2 infection.

11 Mar 2022

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Researchers discovered and optimized cysteine-reactive pyrazoline-based covalent inhibitors for several coronaviruses' Mpro, including SARS-CoV-2.

11 Mar 2022

Catalyst News and Research

Study offers critical clues into longstanding mystery of deep sleep

Researchers reveal how not-yet-malignant cells “turn on” and become metastatic breast cancer

Phase I/II trials of new paratyphoid vaccine begin in Oxford

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

CHEST and Three Lakes Foundation collaborate to reduce delays in diagnosing Interstitial Lung Diseases

New chemical reaction creates a faster, simpler way of making tertiary amines for medicines

$2 million funding to support Friendship Bench program for helping people with mental health issues

Insight into the Breast Cancer Landscape with Breast Cancer Now

Imbalances in the intestinal virome may promote inflammatory bowel disease, research shows

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

Virtual reality psychological therapy shown to work well for patients with mental health problems

Poorly understood brain region may play a key role in how we experience pain

Penn researchers generate functional CAR T cells with enhanced anti-tumor potency in 24 hours

Optical coherence tomography reveals the beating and development of human heart organoids

Highly sensitive PCR test for COVID-19 receives FDA emergency use authorization

Deploying artificial intelligence to prevent delayed and missed care

Zentalis contributes $1 million to SU2C Catalyst program for research into targeted cancer therapeutics

ESGO, ENGAGe and AstraZeneca launch the Ovarian Cancer Commitment

Mild SARS-CoV-2 infection leads to tissue damage and shrinkage in brain areas related to smell

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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