Fibroblast News and Research

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Fibroblasts are connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

Discovery of a T cell subset points to new treatment for COPD exacerbations

Respiratory viral infections pose significant morbidity and mortality to patients with chronic lung diseases like emphysema and COPD, causing exacerbations that drive destruction of normal lung tissue, and leading to one of the most common diagnoses for hospital admissions.

24 Feb 2023

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers found that LRRC15, a TLR-related cell surface receptor, blocked SARS-CoV-2 spike binding.

13 Feb 2023

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

9 Feb 2023

Research reveals the cellular origin of cancer-associated fibroblasts

A type of cell that plays a key role in pancreatic cancer can trace its origin back to a structure that forms during embryonic development, new research at MUSC Hollings Cancer Center shows.

20 Jan 2023

The loss of epigenetic information accelerates the aging process

A new study in the journal Cell aimed to determine whether epigenetic changes are a cause of mammalian aging.

15 Jan 2023

Can diets reverse or delay aging?

A new study published in the journal Science aimed to summarize the commonly studied anti-aging dietary interventions and their impact on human health and longevity.

10 Jan 2023

CU researchers discover a new mechanism for slowing cardiac fibrosis

Researchers at the University of Colorado School of Medicine have discovered a new mechanism for slowing scarring of heart tissue - a process known as cardiac fibrosis.

6 Jan 2023

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

A new research paper was published in Oncotarget's Volume 13 on December 20, 2022, entitled, "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression."

6 Jan 2023

NIH scientists use patient stem cells and 3D bioprinting to produce eye tissue

Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases.

22 Dec 2022

Strontium-loaded hydrogel scaffolds promote wound healing by stimulating gingival fibroblast activity

A team of University at Buffalo researchers has developed a new strontium-loaded scaffold that can be personalized to fit any size dental implant and could help improve healing and tissue attachment in patients.

9 Dec 2022

Study shows how dietary saturated/trans fats promote liver tumorigenesis

Fatty foods harm our health. Prior research has established a link between the consumption of dietary fats and non-alcoholic fatty liver disease, which subsequently leads to inflammation and tumor formation in the liver.

7 Dec 2022

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers evaluated blood plasma proteins to identify new targets for COVID-19 treatment approaches and prevent complications associated with severe illness.

5 Dec 2022

Using cationic nanonmaterials to target visceral adiposity

Researchers have long been working on how to treat obesity, a serious condition that can lead to hypertension, diabetes, chronic inflammation, and cardiovascular diseases.

1 Dec 2022

Newly discovered material can aid healing of hard-to-treat diabetic wounds

Scientists have discovered a new material that can be applied to diabetic wounds to heal them faster with just one application.

29 Nov 2022

New microfluidic Organ Chip platform replicates the human vaginal tissue microenvironment

The human microbiome has been a hot topic over the last decade, with research pointing to disrupted bacterial communities as culprits for a host of maladies including irritable bowel syndrome, eczema, and autoimmune diseases.

28 Nov 2022

Feline coronavirus-infected domesticated cats found to possess cross-reactive anti-SARS-CoV-2 antibodies

In a recent study, researchers confirmed that feline coronavirus infection induced the production of cross-reactive antibodies against the SARS-CoV-2 receptor-binding domain in domestic cats.

28 Nov 2022

Glycan signatures in rheumatic diseases and their associated functional implications

A new paper examines the understanding of glycosylation in an array of rheumatic diseases and indicates the potential for therapeutic interventions using the same mechanism.

28 Nov 2022

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

BGI has currently published over 440 SCI (Science Citation Index) papers in the field of cancer research, with a cumulative impact factor of over 4,000 points.

From BGI Genomics 23 Nov 2022

Cancer Research Horizons, Newcastle University extend strategic drug discovery alliance with Astex Pharmaceuticals

Cancer Research UK’s newly launched innovation engine, Cancer Research Horizons, and Newcastle University, have announced a further significant extension of their strategic drug discovery alliance with Astex Pharmaceuticals (UK) (‘Astex’), a biotechnology company dedicated to the discovery and development of novel small molecule therapeutics.

22 Nov 2022

Time-restricted eating may benefit Alzheimer's

In a recent study published in the Experimental Gerontology journal, researchers in the United States assessed the impact of time-restricted eating (TRE) on Alzheimer's disease (AD), cognitive decline, and sleep.

21 Nov 2022

Fibroblast News and Research

Further Reading

Discovery of a T cell subset points to new treatment for COPD exacerbations

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

Research reveals the cellular origin of cancer-associated fibroblasts

The loss of epigenetic information accelerates the aging process

Can diets reverse or delay aging?

CU researchers discover a new mechanism for slowing cardiac fibrosis

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

NIH scientists use patient stem cells and 3D bioprinting to produce eye tissue

Strontium-loaded hydrogel scaffolds promote wound healing by stimulating gingival fibroblast activity

Study shows how dietary saturated/trans fats promote liver tumorigenesis

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Using cationic nanonmaterials to target visceral adiposity

Newly discovered material can aid healing of hard-to-treat diabetic wounds

New microfluidic Organ Chip platform replicates the human vaginal tissue microenvironment

Feline coronavirus-infected domesticated cats found to possess cross-reactive anti-SARS-CoV-2 antibodies

Glycan signatures in rheumatic diseases and their associated functional implications

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

Cancer Research Horizons, Newcastle University extend strategic drug discovery alliance with Astex Pharmaceuticals

Time-restricted eating may benefit Alzheimer's

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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