Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Regenerative medicine offers a pathway toward curing type 1 diabetes

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells.

26 Nov 2025

Blocking immune cell signals reduces scar tissue formation in wounds

Researchers at the University of Arizona uncovered a previously unknown population of circulating immune cells that play a critical role in fibrosis, the buildup of scar tissue that can lead to organ failure and disfigurement.

25 Nov 2025

CAR T cell therapy could be a highly effective tool against atherosclerosis

A pioneering preclinical study has shown that CAR T cell therapy-a personalized form of immunotherapy used in cancer treatment-could be a highly effective tool against atherosclerosis, the condition where a build-up of plaque in the arteries reduces blood flow, leading to heart attacks and strokes.

21 Nov 2025

New clinical trial shows promise for shorter TB treatment

New clinical trial results presented by TB Alliance at the Union World Conference on Lung Health show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as "SPaL."

19 Nov 2025

BMI is failing to detect dangerous obesity as people age

A landmark study finds waist-to-height ratio more effective than BMI in identifying obesity risk, as central fat levels rise across the UK population.

19 Nov 2025

Preparing for the respiratory virus season: A guide for families

As respiratory virus season begins, pediatric experts are preparing for an expected rise in cases of Respiratory Syncytial Virus (RSV), which can cause cold-like symptoms in most people but serious illness in infants and older adults.

17 Nov 2025

Dash diet cuts diabetes complications by targeting blood pressure kidney health and inflammation

The DASH diet supports metabolic health in people with diabetes by improving blood pressure, renal function, lipids, and modest glycemic markers while reducing risks linked to vascular and inflammatory pathways. Its broad nutrient-driven mechanisms also benefit related conditions such as neuropathy, PCOS, and retinopathy, making it a versatile tool for cardiometabolic care.

16 Nov 2025

Understanding leptin's dual function in MAFLD pathogenesis

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic syndrome.

14 Nov 2025

New precision therapies reshape the future of pancreatitis treatment

Pancreatitis remains a major global health burden, encompassing acute pancreatitis (AP), chronic pancreatitis (CP), and autoimmune pancreatitis (AIP).

11 Nov 2025

Study advances the possibility of age-based pancreatic cancer treatment

While some risk factors for cancer can be mitigated through lifestyle choices such as diet or exercise, aging is not one of them. In the case of pancreatic cancer, it also can limit treatment options if a patient is too frail to be safely treated with surgery or other alternatives.

10 Nov 2025

Genetic and cellular mechanisms underlying steatotic liver disease

Steatotic liver disease (SLD), mainly encompassing metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), and metabolic dysfunction and ALD (MetALD), has emerged as the dominant cause of chronic liver disease worldwide, displacing viral hepatitis as the primary aetiology.

10 Nov 2025

Protein linked to cancer plays key role in wound healing

When doctors detect elevated levels of SerpinB3 in a blood test, it can signal that something is seriously wrong, from hard-to-treat cancers to severe inflammatory conditions.

7 Nov 2025

New insights reveal how TCF and LEF proteins control Wnt signaling and disease progression

Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these proteins as promising therapeutic targets for cancer and fibrotic diseases.

7 Nov 2025

Allergic conditions linked to higher risk of complications after surgery

Two new studies being presented at the 2025 Annual Scientific Meeting of the American College of Allergy, Asthma and Immunology (ACAAI) show that people with allergic conditions - including eczema, asthma, and hay fever - may face more problems after certain types of surgery.

6 Nov 2025