Glioma News and Research

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Glioma is a cancer of the brain that begins in glial cells (cells that surround and support nerve cells).

Disrupting DNA loops could be potential strategy to reduce tumor proliferation

The discovery of a mechanism by which normal brain cells regulate the expression of the NFIA gene, which is important for both normal brain development and brain tumor growth, might one day help improve therapies to treat brain tumors. The study appears in the journal Nature Neuroscience.

13 Sep 2017

Japanese researchers find new way for increasing effectiveness of drug delivery to brain tumors

For a cancer drug to be successful, it needs to reach the malignant tumor site. Researchers in Japan have now found a way for increasing the effectiveness of drug delivery to certain types of brain tumors, by packing epirubicin, a known antitumor agent, in specially designed polymeric micelles.

13 Sep 2017

Disease diagnostic tools win top honors in DEBUT challenge

Tools to diagnose Alzheimer's disease and latent tuberculosis are among the winning projects in the Design by Biomedical Undergraduate Teams (DEBUT) challenge, a biomedical engineering design prize competition for teams of undergraduate students.

26 Aug 2017

Researchers identify new factors that may affect brain tumor cells' ability to resist treatment

The most aggressive variant of brain tumor - glioblastoma - has an average survival rate of 15 months. There is therefore an urgent need for new treatment strategies for this group of patients.

16 Aug 2017

New guidelines may lead to better management of patients with glioma

A University of Portsmouth academic has helped to develop European guidelines to treat brain tumors more effectively.

10 Aug 2017

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Glioblastoma is a primary brain tumor with dismal survival rates, even after treatment with surgery, chemotherapy, and radiation.

25 Jul 2017

New treatment strategy may destroy difficult-to-treat brain tumors

A new strategy for treating brain tumors may extend or save the lives of patients diagnosed with one of the deadliest forms of cancer, according to a study from UT Southwestern Medical Center.

13 Jun 2017

Study suggests promising therapeutic strategy for childhood brain tumor

A study published in Molecular Cancer Research reveals that a tumor suppressor gene p16 is turned off by a histone mutation (H3.3K27M), which is found in up to 70 percent of childhood brain tumors called diffuse intrinsic pontine glioma (DIPG).

6 Jun 2017

Changes in immune activity appear to signal brain tumor growth five years before diagnosis, study finds

Changes in immune activity appear to signal a growing brain tumor five years before symptoms arise, new research has found.

2 Jun 2017

Investigational compound inhibits cancer-specific mutations in mice

Many malignancies develop as a result of genetic alterations in individual cells. These gene mutations often cause altered proteins that give new, growth-promoting properties to the cell.

30 May 2017

Researchers identify DNA repair deficiency in many types of solid tumors

A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.

18 May 2017

Research sheds new light on surprising link between blood sugar and brain cancers

New research further illuminates the surprising relationship between blood sugar and brain tumors and could begin to shed light on how certain cancers develop.

3 May 2017

Scientists map genetic changes that help drive aggressive brain tumor

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have mapped genetic changes that help drive an aggressive tumor as it develops in the brain – helping to lay the foundation for targeted treatment of the disease.

3 May 2017

Molecular drug imaging likely to benefit children with brain tumors

Brain cancers are difficult to treat, and it can be hard to predict whether a therapy will be effective. When the patient is a child, it's even more important to predict the potential effectiveness of a drug before beginning treatment.

3 May 2017

NUS researchers develop novel dual-mode contrast agent for better liver cancer imaging

Scientists from the National University of Singapore have developed a novel nanodiamond-based contrast agent - a chemical "dye" used to enhance the visibility of internal body structures in magnetic resonance imaging - that improves visualization of liver cancer tumors

2 May 2017

Study examines post-operative seizure outcomes after insular tumor resection

Winner of the Journal on Neuro-Oncology Award sponsored by Kluwer Academic Publishers, Doris Du Wang, MD, presented her research, Seizure Outcome After Surgical Resection of Insular Glioma, during the 2017 American Association of Neurological Surgeons Annual Scientific Meeting.

26 Apr 2017

Researcher aims to eliminate chemotherapy-resistant ovarian tumors using virus treatment

In some cases, the Lassa virus starts with a fever and general weakness, moving toward headache, muscle pain, possible facial swelling, deafness, and worse. About 15 percent of patients hospitalized with severe cases die.

20 Apr 2017

PID1 gene increases killing effect of chemotherapy drugs on brain tumor cells

Investigators at The Saban Research Institute of Children's Hospital Los Angeles have found that the gene PID1 enhances killing of medulloblastoma and glioblastoma cells.

11 Apr 2017

Feinstein Institute research may lead to new treatment option for low-grade gliomas

Marc Symons, PhD, professor in The Feinstein Institute for Medical Research's Karches Center for Oncology Research, is examining if a common medication administered to treat pinworms, could replace the current treatment used for certain brain cancers.

11 Apr 2017

Study explains how genetic mutations linked to telomere capping complex contribute to cancers

Scientists at The Wistar Institute have unveiled part of the protein complex that protects telomeres-;the ends of our chromosomes. The study, published online in Nature Communications, explains how a group of genetic mutations associated with this protein complex contributes to various cancers.

10 Apr 2017

Glioma News and Research

Further Reading

Disrupting DNA loops could be potential strategy to reduce tumor proliferation

Japanese researchers find new way for increasing effectiveness of drug delivery to brain tumors

Disease diagnostic tools win top honors in DEBUT challenge

Researchers identify new factors that may affect brain tumor cells' ability to resist treatment

New guidelines may lead to better management of patients with glioma

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

New treatment strategy may destroy difficult-to-treat brain tumors

Study suggests promising therapeutic strategy for childhood brain tumor

Changes in immune activity appear to signal brain tumor growth five years before diagnosis, study finds

Investigational compound inhibits cancer-specific mutations in mice

Researchers identify DNA repair deficiency in many types of solid tumors

Research sheds new light on surprising link between blood sugar and brain cancers

Scientists map genetic changes that help drive aggressive brain tumor

Molecular drug imaging likely to benefit children with brain tumors

NUS researchers develop novel dual-mode contrast agent for better liver cancer imaging

Study examines post-operative seizure outcomes after insular tumor resection

Researcher aims to eliminate chemotherapy-resistant ovarian tumors using virus treatment

PID1 gene increases killing effect of chemotherapy drugs on brain tumor cells

Feinstein Institute research may lead to new treatment option for low-grade gliomas

Study explains how genetic mutations linked to telomere capping complex contribute to cancers

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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