Musculoskeletal News and Research

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New EULAR recommendations provide updated treatment strategies for systemic sclerosis

SSc is a rare connective tissue disorder, with both autoimmune and vascular features. The main hallmark is tissue and vascular fibrosis that can result in clinical heterogeneity of manifestations across the skin and internal organs.

14 Oct 2024

Protein discovery offers insights into bone health and potential treatments for osteoporosis

Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation, a new study has found.

12 Oct 2024

New study links persistent SARS-CoV-2 proteins to long COVID symptoms

Brigham researchers found people with wide-ranging long COVID symptoms were twice as likely to have SARS-CoV-2 proteins in their blood, compared to those without long COVID symptoms.

9 Oct 2024

Overcoming CRISPR's side effects for therapeutic applications

CRISPR is a revolutionary tool that allows scientists to precisely modify the genome and gene expression of cells in any organism. It's a reagent - a substance that facilitates a reaction - that combines an enzyme with a programmable RNA capable of locating specific genetic sequences. Once guided to the correct spot, the enzyme acts like a pair of scissors, cutting, replacing, or deleting sequences of DNA.

7 Oct 2024

Houston Methodist researchers join national consortium to develop herpesvirus vaccine

Houston Methodist researchers will be part of a national consortium funded by an up to $49 million award from the U.S. Government's Advanced Research Projects Agency for Health (ARPA-H) to develop a vaccine against two of the most common and destructive strains of herpesviruses that latently infect a majority of Americans and can lead to acute infections, multiple forms of cancer, autoimmune disease and birth defects.

3 Oct 2024

Accelerating tobacco decline could boost global life expectancy

Accelerating the decline in tobacco smoking globally, by decreasing smoking prevalence from current levels to 5% everywhere, could increase life expectancy and prevent millions of premature deaths by 2050, according to a study from the Global Burden of Disease, Injuries and Risk Factors (GBD) Tobacco Forecasting Collaborators published in The Lancet Public Health journal.

3 Oct 2024

Perceived stress can directly trigger psoriasis relapse

Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin lesions. The study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, is the first to scientifically validate this connection in vivo.

26 Sep 2024

Study aims to uncover sex-specific causes of shoulder pain in wheelchair users

Josh Leonardis received funding from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health to study why female manual wheelchair users experience shoulder pain and pathology at greater rates than males.

23 Sep 2024

Primary care physicians face rising complexity of mental health concerns

An examination of millions of patient visits to primary care physicians shows that mental health concerns are second only to musculoskeletal complaints in everyday care.

19 Sep 2024

Study highlights disparities in stroke burden across regions

Although stroke is highly preventable and treatable, there has been a rapid rise in the global stroke burden between 1990 and 2021, due to both population growth and the rise of aging populations worldwide, as well as a substantial increase in people's exposure to environmental and behavioral risk factors.

19 Sep 2024

UC San Diego Health trials spatial computing technology in operating room

Minimally invasive surgeons at UC San Diego Health are the first in the nation to evaluate the potential use of spatial computing apps on Apple Vision Pro in the operating room.

17 Sep 2024

Loneliness may not be a direct cause of disease

A study reveals loneliness correlates with 13 illness categories, highlighting its role as a potential proxy marker rather than a direct risk factor.

17 Sep 2024

Study highlights limited evidence for antidepressants in treating pain in older adults

University of Sydney research has found people over 65 are being prescribed antidepressants as pain treatment based on international guidelines that use limited evidence.

16 Sep 2024

Study links excess abdominal fat with widespread chronic pain

Excess abdominal fat is associated with widespread chronic pain, particularly in women, finds the first study of its kind, published in the open access journal Regional Anesthesia & Pain Medicine.

10 Sep 2024

Expert survey unveils underestimated health impacts of weather and climate on mortality

The study analyzes expert views on climate's role in mortality, linking weather hazards to health outcomes and highlighting urgent preventive strategies.

10 Sep 2024

Long COVID significantly affects children for up to 36 months, vaccines offer crucial protection

Study reveals the significant and lasting impact of long COVID on children, emphasizing the protective role of vaccines and the increased risk of autoimmune disorders.

8 Sep 2024

Addressing the physical health risks related to excessive video gaming

Gaming is a popular activity, especially for young people – and with summer drawing to a close, more and more children may be opting to spend time playing video games as opposed to enjoying time outdoors.

6 Sep 2024

High-precision X-rays uncover the mechanics of neck pain

Learning new languages, sending emails, attending a virtual class, or speaking to loved ones halfway around the world are just some of the tasks accomplished by touching a button on a smartphone. Unfortunately, the ease and convenience of modern devices have also come with a painful crick in the neck. The sedentary nature of work and prolonged use of hand-held devices and computers have contributed to a sharp increase in neck pain.

5 Sep 2024

Study reveals ChatGPT-4 Vision's strengths and weaknesses in radiology exam performance

Researchers evaluating the performance of ChatGPT-4 Vision found that the model performed well on text-based radiology exam questions but struggled to answer image-related questions accurately.

3 Sep 2024

Penn research uncovers key biomarker for diagnosing sarcoidosis

Sarcoidosis is a rare systemic disease that afflicts an estimated 200,000 people in the US, more often people who are Black and more women than men, particularly when it causes chronic skin disease.

3 Sep 2024