Ribosome News and Research

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Defective ribosomes linked to aggressive form of multiple myeloma

20 to 40 percent of the patients with multiple myeloma - a type of leukaemia - have a defect in the ribosome, the protein factory of the cell.

9 Dec 2016

Scientists discover ribosomal protein-based cancer signature

A research team at the University of Basel's Biozentrum has investigated the expression of ribosomal proteins in a wide range of human tissues including tumors and discovered a cancer type specific signature.

6 Dec 2016

Scientists develop safe, highly efficient method to improve searching of new germicides

Scientists from the Lomonosov Moscow State University in cooperation with colleagues have worked out a safe, not that expensive and highly efficient method, which allows to speed up and improve searching of new germicides.

29 Nov 2016

Two widely prescribed antibiotics may combat bacteria differently than previously thought

Two widely prescribed antibiotics -- chloramphenicol and linezolid -- may fight bacteria in a different way from what scientists and doctors thought for years, University of Illinois at Chicago researchers have found.

2 Nov 2016

Researchers discover how toxic proteins linked to neurological diseases impair membrane-less organelles

Researchers at St. Jude Children's Research Hospital have discovered the way toxic proteins linked to the most common forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) incapacitate membrane-less organelles inside cells.

21 Oct 2016

Scientists find how selenium gets integrated into protein molecules

Humans need eight essential trace elements for good health, and one of them is selenium - a powerful antioxidant that is important for thyroid and brain function as well as metabolism.

6 Oct 2016

Research finds evidence linking number of ribosomal genes to bacterial growth rate and efficiency

Microbes that can reproduce rapidly in times of plenty have an evolutionary stockpile of extra genes that allows them to quickly respond to changing conditions such as oil spills or outbreaks of intestinal diseases.

3 Oct 2016

Researchers discover how cells know when to stop producing mRNA

A new scientific study conducted by a team of leading geneticists has characterized how cells know when to stop translating DNA into proteins, a critical step in maintaining healthy protein levels and cell function.

30 Sep 2016

Scientists identify molecule in liver cells that regulates release of fats into the bloodstream

ETH researchers have discovered a molecule in liver cells that controls the release of fat into the bloodstream. This "lock keeper" is present in large quantities in overweight people and leads indirectly to vascular narrowing.

28 Sep 2016

Researchers identify tantalizing target in fight against aggressive form of lung cancer

Researchers at the University of Virginia School of Medicine have discovered a flaw in the armor of the most aggressive form of lung cancer, a weakness that doctors may be able to exploit to slow or even stop the disease.

19 Aug 2016

Curza receives SBIR grant to develop new class of broad spectrum antibiotics

Curza Global, LLC, a company based on technology developed at the University of Utah, has been awarded a Phase I Small Business Innovation Research grant of $598,770 entitled "Natural product-inspired antibacterials with unique ribosomal binding" that will provide two years of support.

7 Jul 2016

Scientists discover unexpected functions of snoRNAs that explains cause of some diseases

Scientists have discovered unexpected functions of small nucleolar RNAs (snoRNAs) that explain the cause of some diseases.

7 Jun 2016

RNA molecular dynamics research provides key insights into new treatments for retroviral diseases

New molecular dynamics research into how RNA folds into hairpin-shaped structures called tetraloops could provide important insights into new treatments for retroviral diseases.

1 Jun 2016

Unlocking the dark proteome: an interview with Dr Kriwacki

The term dark proteome refers to proteins whose structural features and thus functions are not well understood. Many proteins within the dark proteome do not fold into stable three-dimensional structures. These proteins are called intrinsically disordered proteins (IDPs) and feature highly flexible, disordered confirmations.

16 May 2016

Scientists develop new technology that helps visualize translation of mRNA into proteins

For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to "see" single molecules of messenger RNA as they are translated into proteins in living mammalian cells. Initial findings using this technology that may shed light on neurological diseases as well as cancer were published online today in Science.

9 May 2016

MIT researchers develop innovative paper-based test to diagnose Zika virus

A new paper-based test developed at MIT and other institutions can diagnose Zika virus infection within a few hours. The test, which distinguishes Zika from the very similar dengue virus, can be stored at room temperature and read with a simple electronic reader, making it potentially practical for widespread use.

9 May 2016

High-throughput RNA interference screen identifies potential drug target against henipaviruses

The closely related Hendra and Nipah viruses (referred to jointly as henipaviruses) are deadly cousins of the more common mumps, measles, and respiratory syncytial viruses, all members of the paramyxovirus family. Henipavirus outbreaks are on the rise, but little is known about them, partly because research has to be conducted under extreme level containment conditions.

28 Mar 2016

Study provides better picture of molecular basis for antibiotic resistance

Scientists from the University of Leeds have solved a 25-year-old question about how a family of proteins allow bacteria to resist the effects of certain antibiotics.

23 Mar 2016

Role of dietary restriction in lifespan extension

The role of dietary restriction in extending lifespan is the subject of research being conducted at the MDI Biological Laboratory in Bar Harbor, Maine, by visiting scientist Markus Schosserer, Ph.D., of the biotechnology department at the University of Natural Resources and Life Sciences, Vienna, in Austria.

22 Mar 2016

TSRI researchers uncover new molecular mechanism underlying neurodegenerative diseases

A new study led by scientists at The Scripps Research Institute suggests that cells construct protein "clumps" to protect against neurodegenerative diseases such as amyotrophic lateral sclerosis, a.k.a. ALS or Lou Gehrig's disease.

10 Mar 2016