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Protein implicated in neuron growth and cell adhesion appears crucial for pain sensitization

Researchers from Japan's Osaka University have made an important leap in our understanding of how chronic pain conditions develop.

20 Aug 2019

Protein plays important roles in intracellular membrane trafficking in the brain

Our bodies couldn’t operate without the central nervous system - a complex network that coordinates our actions, reflexes, and sensations. Each neuron in your brain has one long cable that snakes away from the main part of the cell.

20 Aug 2019

Alzheimer’s disease risk gene is involved in synaptic transmission

A study published today in the journal Cell Reports sheds new light on how the CD2AP gene may enhance Alzheimer's disease susceptibility.

14 Aug 2019

Antibody target implicated in neuropsychiatric symptoms of lupus discovered

Researchers have identified a specific target of antibodies that are implicated in the neuropsychiatric symptoms of lupus, according to human research published in JNeurosci.

From Society for Neuroscience 13 Aug 2019

Researchers identify direct toxic action of beta-amyloid in the brain

The brains of Alzheimer's patients who have already developed clinical symptoms contain large clumps of the protein beta-amyloid, known as plaques. Many therapeutic approaches focus on removing plaques, but such attempts have met with only limited success to date.

9 Aug 2019

Alzheimers may be linked to genes that code formation of contacts between neurons

A team of neurobiologists from Peter the Great St. Petersburg Polytechnic University published an article on their study of the causes of Alzheimer's disease and suggested therapy methods.

2 Aug 2019

Super-resolution microscopy helps unravel elusive causes of dementia

University of Queensland researchers have used super-resolution microscopy to observe key molecules at work inside living brain cells, further unraveling the puzzle of memory formation and the elusive causes of dementia.

2 Aug 2019

Astrocytic MORs in the hippocampus responsible for conditioned place preference

If somebody asks me "are you a coffee addict?" I may say, "Yeah it seems like, but on the one condition, only in my office." I don't have that much craving for coffee at home, but just being in the office, where I used to drink coffee all the time seeking to get caffeine jitters, seems to trigger my caffeine-addicted brain.

31 Jul 2019

International doctors uncover genes that contribute to five psychiatric disorders

A group of international doctors has uncovered the genes that contribute to the development of ADHD, autism spectrum disorder, bipolar disorder, major depression and schizophrenia.

24 Jul 2019

Brain protein mutation from an autistic person alters behavior in mice

A de novo gene mutation that encodes a brain protein in a child with autism has been placed into the brains of mice.

24 Jul 2019

Gene mutation in the brain of autism patients alters behaviors in mice

Autism spectrum disorder (ASD) has a wide range of possible causes, including genetics and environmental factors. Now, a new study suggests that a brain protein mutation may shed light on the mechanism of neurological and developmental illness.

23 Jul 2019

New study reveals 'clutch' proteins responsible for putting T cell activation 'into gear'

In collaborative research, scientists from three continents were able to discover a crucial bit of information about how T cells move proteins inside them to drive the immune response. This could help evolve specific new treatments centered on T cell selectivity.

12 Jul 2019

Scientists reveal insights into how a common Alzheimer's risk gene disrupts brain cells

Insights into how a gene that increases the risk of Alzheimer's disease disrupts brain cells have been revealed by scientists.

27 Jun 2019

'Food for special medical purposes' can benefit patients with earliest stages of Alzheimer's disease

Study supports the hypothesis that a food for special medical purposes containing Fortasyn Connect can benefit patients with mild cognitive impairment who are at high risk of progression to the dementia stage of Alzheimer's disease, according to research published in the Journal of Alzheimer's Disease Reports.

13 Jun 2019

Drink containing multinutrient combination can benefit patients with mild cognitive impairment

Study supports the hypothesis that a food for special medical purposes containing Fortasyn Connect® can benefit patients with mild cognitive impairment who are at high risk of progression to the dementia stage of Alzheimer's disease, according to research published in the Journal of Alzheimer's Disease Reports

13 Jun 2019

Graphene flakes may influence the action of brain cells

Like in a science fiction novel, miniscule spacecrafts able to reach a specific site of the brain and influence the operation of specific types of neurons or drug delivery: graphene flakes, the subject matter of the new study of the group of SISSA professor Laura Ballerini, open up truly futuristic horizons.

10 May 2019

Neuroscientists propose new theory about amyloid precursor protein connection in Alzheimer's

Worldwide, 50 million people are living with Alzheimer's disease and other dementias. According to the Alzheimer's Association, every 65 seconds someone in the United States develops this disease, which causes problems with memory, thinking and behavior.

23 Apr 2019

Researchers identify ketamine-induced neural changes responsible for remission of depression

Researchers have identified ketamine-induced brain-related changes that are responsible for maintaining the remission of behaviors related to depression in mice -- findings that may help researchers develop interventions that promote lasting remission of depression in humans.

12 Apr 2019

Gene therapy restores hearing in mice with congenital genetic deafness

In collaboration with the universities of Miami, Columbia and San Francisco, scientists from the Institut Pasteur, Inserm, CNRS, Collège de France, Sorbonne University and the University of Clermont Auvergne have managed to restore hearing in an adult mouse model of DFNB9 deafness - a hearing disorder that represents one of the most frequent cases of congenital genetic deafness.

19 Feb 2019

Interaction between two immune cells may play key role in fight against dengue virus

Researchers at Duke-NUS Medical School have demonstrated for the first time a physical interaction between two types of immune cells that plays an important role in the early fight against dengue virus infection.

8 Feb 2019