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Researchers develop new electrophoretic method for detecting MIRCERA and EPO in blood

Austrian researchers have successfully developed a new electrophoretic method for detecting MIRCERA® and other erythropoietins (EPO) in the blood. The technique, using SARCOSYL-PAGE, has specifically enhanced sensitivity for MIRCERA, but does not alter the performance characteristics of SDS-PAGE for detecting other EPOs.

16 Dec 2009

Cell Biosciences expands its protein analysis business with Protein Forest acquisition

Cell Biosciences, Inc. today announced that it has acquired Protein Forest, Inc. of Lexington, Massachusetts, a leader in sample preparation technology for proteomic analysis and biomarker discovery.

7 Dec 2009

OriGene Technologies' over-expression lysates adopted for Human Protein Atlas project

OriGene Technologies, Inc. today announced Royal Institute of Technology in Sweden has adopted its VERIFY Tagged Antigen(TM) (Over-expression Lysates) in the Human Protein Atlas program. This program is funded by the Knut and Alice Wallenberg Foundation and is set up to explore the human proteome systematically using Antibody-Based Proteomics.

10 Nov 2009

Precision Antibody to develop antibodies for NCI's Clinical Proteomic Technologies for Cancer

Precision Antibody(TM) has been selected as the antibody developer for a component of the National Cancer Institute (NCI)'s Clinical Proteomic Technologies for Cancer (CPTC), which is focused on improving the number and standardizing the quality of monoclonal antibody reagents available for clinical cancer proteomics research.

28 Oct 2009

Emodin raises hope for treatment of fibrotic liver diseases

In the last decade, advances in the understanding of genes promoting hepatic stellate cell (HSC) activation are impressive. However, there are few breakthroughs in therapeutic intervention of hepatic fibrogenesis. Efficient and well-tolerated antifibrotic drugs are lacking and current treatment of hepatic fibrosis is limited to withdrawal of the noxious agent. Research identifying innocuous antifibrotic agents is of high priority and urgently needed.

24 Oct 2009

Chrysanthemum indicum extract holds promise for treating human cancer

A series of studies have demonstrated that Chrysanthemum indicum possesses antimicrobial, antiinflammatory, immunomodulatory, and neuroprotective effects. Recently, much attention has been devoted to the anticancer activity of Chrysanthemum indicum, especially in hepatocellular carcinoma (HCC). However, its anticancer mechanism of action is still not clear and needs further investigation.

19 Oct 2009

Study looks at shikonin for human gastric adenocarcinoma

Previous studies on shikonin, a chemical derived from the Chinese medicinal herb had anti-tumor effects although it was found to be toxic.

20 Apr 2009

Mammalian alpha-fetoprotein affects the development of rat colons

Mammalian alpha-fetoprotein (AFP) is a single-chain glycoprotein and altered serum AFP levels have been observed concurrent with aberrant growth manifestations in some congenital defects and cancer.

20 Apr 2009

A potential therapeutic target for gastric cancer

Gastric cancer (GC) is the fourth most common malignancy and the second most frequent cause of cancer-related death in the world.

20 Apr 2009

Cigarette smoke may reshape the left ventricle

Prolonged exposure to cigarette smoke can increase levels of the stress hormone norepinephrine and enzymes in the heart that have the potential to reshape the left ventricle, according to new research at the University of Illinois at Chicago.

16 Nov 2008

Mother's immune system may play role in chilld's autism

The mothers of some autistic children may have made antibodies against their fetuses' brain tissue during pregnancy that crossed the placenta and caused changes that led to autism, suggests research led by Johns Hopkins Children's Center investigators and published in the February issue of the Journal of Neuroimmunology.

26 Feb 2008

Some cases of autism may be traced to the immune system of mothers during pregnancy

New research from the UC Davis M.I.N.D. Institute and Center for Children's Environmental Health has found that antibodies in the blood of mothers of children with autism bind to fetal brain cells, potentially interrupting healthy brain development.

12 Feb 2008

Trial of repeated antibiotic therapy for Lyme diseases

Findings from the first placebo-controlled study of chronic cognitive impairment after treated Lyme disease (also known as chronic Lyme encephalopathy) demonstrate that patients report moderate cognitive impairment, physical dysfunction comparable to patients with congestive heart failure, and fatigue comparable to patients with multiple sclerosis.

10 Oct 2007

Discovery of two new proteins associated with colorectal cancer

Researchers at the Zhejiang University, Hangzhou have discovered that mimecan and Thioredoxin Domain-Containing Protein 5 (TXNDC5) were differentially expressed in colorectal adenoma.

25 Sep 2007

Gay pride events offer opportunity to identify new HIV cases among MSM

Gay pride events provide opportunities outside of health care settings to identify new HIV cases among men who have sex with men, particularly among MSM in racial and ethnic minorities, according to a study published in the June 22 edition of CDC's Morbidity and Mortality Weekly Report, Reuters Health reports (Reuters Health, 6/21).

22 Jun 2007

Decoy receptor 3 expressed in rheumatic synovial fibroblasts protects the cells against Fas-induced apoptosis

A complex autoimmune disease, rheumatoid arthritis (RA) is characterized by chronic inflammation and progressive joint damage. This process begins with hyperplasia, or excessive increase in size and thickness, of synovial tissue. Along with provoking cartilage and bone destruction, this abnormal tissue growth is resistant to apoptosis, the natural cell death vital to the generation of healthy new cells.

30 Mar 2007

Western Blot News and Research

Researchers develop new electrophoretic method for detecting MIRCERA and EPO in blood

Cell Biosciences expands its protein analysis business with Protein Forest acquisition

OriGene Technologies' over-expression lysates adopted for Human Protein Atlas project

Precision Antibody to develop antibodies for NCI's Clinical Proteomic Technologies for Cancer

Emodin raises hope for treatment of fibrotic liver diseases

Chrysanthemum indicum extract holds promise for treating human cancer

Study looks at shikonin for human gastric adenocarcinoma

Mammalian alpha-fetoprotein affects the development of rat colons

A potential therapeutic target for gastric cancer

Cigarette smoke may reshape the left ventricle

Mother's immune system may play role in chilld's autism

Some cases of autism may be traced to the immune system of mothers during pregnancy

Trial of repeated antibiotic therapy for Lyme diseases

Discovery of two new proteins associated with colorectal cancer

Gay pride events offer opportunity to identify new HIV cases among MSM

Decoy receptor 3 expressed in rheumatic synovial fibroblasts protects the cells against Fas-induced apoptosis

FDA approves test to help diagnose HIV

Case definitions for human infections with influenza A (H5N1) virus

Active mind and body slows Alzheimer's progression

Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheep

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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