Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Engineered mouse Intestine Chip platform can help study host-microbiome interactions

Trillions of commensal microbes live on the mucosal and epidermal surfaces of the body and it is firmly established that this microbiome affects its host's tolerance and sensitivity of the host to a variety of pathogens.

16 Mar 2021

Researchers identify a possible cause of functional neurological disorder

Researchers believe they may have discovered a possible cause of a mystery condition that can leave sufferers suddenly unable to walk, talk or see.

16 Mar 2021

Researchers identify epigenetic mechanism responsible for lifelong stress susceptibility

An epigenetic modification that occurs in a major cell type in the brain's reward circuitry controls how stress early in life increases susceptibility to additional stress in adulthood, researchers at the Icahn School of Medicine at Mount Sinai have learned.

15 Mar 2021

MGH researchers uncover new clues about X chromosome inactivation

Researchers at Massachusetts General Hospital have uncovered new clues that add to the growing understanding of how female mammals, including humans, "silence" one X chromosome.

15 Mar 2021

Study shows evidence-based interventions can improve infant brain health

In the world of neurodevelopment, one thing is clear: the earlier the intervention the better. Infancy is a critical time in brain development, and neuroscientists are increasingly identifying factors that can negatively impact cognition and ones that can improve cognition early in life.

15 Mar 2021

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

Researchers in the United States have conducted a study showing that a cannabis plant compound inhibited infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human lung cells.

14 Mar 2021

Novel computer-guided design tool helps increase the efficiency of cell conversions

There is a great need to generate various types of cells for use in new therapies to replace tissues that are lost due to disease or injuries, or for studies outside the human body to improve our understanding of how organs and tissues function in health and disease.

13 Mar 2021

Random cellular changes play vital role in longevity beyond genetics and environment

A new model of aging takes into account not only genetics and environmental exposures but also the tiny changes that randomly arise at the cellular level.

13 Mar 2021

Otago researchers find how to treat heart disease in type-2 diabetics

University of Otago researchers have discovered one of the reasons why more than 50 per cent of people with type 2 diabetes die from heart disease.

12 Mar 2021

SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment, study finds

Researchers have found that SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment. Therefore, strategies such as focusing on limiting the production of IFN, rather than its function, could restrict the mechanism of SARS-CoV-2 that increases its viral load with delayed or absent symptoms.

12 Mar 2021

Living in neighborhoods with high rates of violence and poverty alters gene activity

The chronic stress of living in neighborhoods with high rates of violence and poverty alters gene activity in immune cells, according to a new study of low-income single Black mothers on the South Side of Chicago.

12 Mar 2021

RNA editing events influence gene expression and phenotypic manifestation

Combining computational mining of big data with experimental testing in the lab, researchers at Children's Hospital of Philadelphia (CHOP) have identified RNA editing events that influence gene expression and, in turn, the phenotypic manifestation of that expression.

10 Mar 2021

Researchers develop AI-based tissue-section analysis system to diagnose breast cancer

Researchers at Charité - Universitätsmedizin Berlin and TU Berlin as well as the University of Oslo have developed a new tissue-section analysis system for diagnosing breast cancer based on artificial intelligence (AI).

10 Mar 2021

Impairments in immune response contribute to severe COVID-19

New research by a team of scientists at University Hospital RWTH Aachen in Germany and Erasmus Medical Centre in The Netherlands characterized changes in CD8+ T cells in response to SARS-CoV-2.

8 Mar 2021

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection

A new paper in the journal Life presents an early review of the viral factors involved in initiating and effecting apoptosis within infected cells.

8 Mar 2021

Using decision theory for precise choice of breast cancer treatment

The precise choice of treatment for breast cancer depends upon the status of the hormone receptors (for oestrogen and progesterone). Their conventional determination by means of immunohistochemistry (IHC) is associated with a certain error rate, which can be reduced by adding genomic data.

8 Mar 2021

Review helps understand the mechanisms of R-CHOP resistance in diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer of lymphocytes, and a large proportion of patients are either unresponsive or develop resistance towards R-CHOP—the standard treatment regimen.

8 Mar 2021

Eight hallmarks of environmental exposures that contribute to disease

A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations and mutations, epigenetic alterations, mitochondrial dysfunction, endocrine disruption, altered intercellular communication, altered microbiome communities, and impaired nervous system function.

5 Mar 2021

SARS-CoV-2 proteins are potent suppressors of innate immunity

A new study describes the strong immune-suppressing activity of SARS-CoV-2 genes, among other coronavirus genes.

5 Mar 2021

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets.

4 Mar 2021

Gene Expression News and Research

Further Reading

Engineered mouse Intestine Chip platform can help study host-microbiome interactions

Researchers identify a possible cause of functional neurological disorder

Researchers identify epigenetic mechanism responsible for lifelong stress susceptibility

MGH researchers uncover new clues about X chromosome inactivation

Study shows evidence-based interventions can improve infant brain health

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

Novel computer-guided design tool helps increase the efficiency of cell conversions

Random cellular changes play vital role in longevity beyond genetics and environment

Otago researchers find how to treat heart disease in type-2 diabetics

SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment, study finds

Living in neighborhoods with high rates of violence and poverty alters gene activity

RNA editing events influence gene expression and phenotypic manifestation

Researchers develop AI-based tissue-section analysis system to diagnose breast cancer

Impairments in immune response contribute to severe COVID-19

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection

Using decision theory for precise choice of breast cancer treatment

Review helps understand the mechanisms of R-CHOP resistance in diffuse large B-cell lymphoma

Eight hallmarks of environmental exposures that contribute to disease

SARS-CoV-2 proteins are potent suppressors of innate immunity

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

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