Proliferation News and Research

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Stem cell research offers alternative view of cancer metastasis

Stem cells are among the most energetically activated, migratory and proliferative sub-populations of tumour cells, according to observations by scholars at the Biomedical Research Centre at the University of Salford.

18 Jan 2017

UIC chemists pinpoint role of cholesterol in cells

Scientists have long puzzled over cholesterol. It's biologically necessary; it's observably harmful - and nobody knows what it's doing where it's most abundant in cells: in the cell membrane.

18 Jan 2017

UVC machines can cut transmission of four drug-resistant superbugs by 30%, study finds

A new tool -- a type of ultraviolet light called UVC -- could aid hospitals in the ongoing battle to keep drug-resistant bacteria from lingering in patient rooms and causing new infections.

17 Jan 2017

Nanoparticle exposure can trigger dormant viruses in lung tissue cells

Nanoparticles from combustion engines can activate viruses that are dormant in lung tissue cells. This is the result of a study by researchers of Helmholtz Zentrum München, a partner in the German Center for Lung Research, which has now been published in the journal 'Particle and Fibre Toxicology'.

16 Jan 2017

Researchers move one step closer to regenerating heart wall using stem cells

A process using human stem cells can generate the cells that cover the external surface of a human heart -- epicardium cells -- according to a multidisciplinary team of researchers.

12 Jan 2017

Scientists gain new insights into molecular mechanisms of breast cancer development

Why does breast cancer develop and how come certain patients are resistant to established therapies? Researchers from the University of Basel have gained new insights into the molecular processes in breast tissue.

9 Jan 2017

Dutch scientists discover favorable conditions for growth of Legionella bacteria

The bacteria that cause Legionnaire's disease grow well in warm tap water installations with ample dissolved organic matter--conditions that support the growth of biofilms. The research is published January 6th in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.

6 Jan 2017

Northwestern Medicine scientists identify targeted molecular therapy that halts childhood leukemia

Northwestern Medicine scientists have discovered the genetic driver of a rare and lethal childhood leukemia and identified a targeted molecular therapy that halts the proliferation of leukemic cells.

6 Jan 2017

Researchers uncover two factors that play crucial role in chronic autoimmune disorders

Researchers from Schepens Eye Research Institute of Massachusetts Eye and Ear have uncovered two factors responsible for the chronic, lifelong nature of autoimmune disorders, which tend to "flare up" intermittently in affected patients.

4 Jan 2017

Study offers new insights into mechanisms underlying action of motor proteins

A study published today offers a new understanding of the complex cellular machinery that animal and fungi cells use to ensure normal cell division, and scientists say it could one day lead to new treatment approaches for certain types of cancers.

4 Jan 2017

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study.

3 Jan 2017

Specific gene pathway appears to regulate growth, structure, and organization of cerebral cortex

One of the most significant ways in which the human brain is unique is the size and structure of the cerebral cortex. But what drives the growth of the human cortex, likely the foundation for our unique intellectual abilities?

30 Dec 2016

Myc genes play key role in self-renewal of spermatogonial stem cells

Sperm are constantly replenished in the adult male body. Understanding the workings of stem cells responsible for this replenishment is expected to shed light on why male fertility diminishes with age, and possibly lead to new treatments for infertility.

28 Dec 2016

Combination of diabetes and hypertension drugs can effectively treat cancer

A combination of a diabetes medication and an antihypertensive drug can effectively combat cancer cells.

27 Dec 2016

New research points to lncRNA's key role in helping control cellular processes

Scientific research over the past decade has concentrated almost exclusively on the 2 percent of the genome's protein coding regions, virtually ignoring the other 98 percent, a vast universe of non-coding genetic material previously dismissed as nothing more than 'junk.'

27 Dec 2016

Scientists unravel novel role of signalling protein in common type of liver cancer

The most common type of liver cancer, called Hepatocellular carcinoma, is one of the most prevalent tumours worldwide.

21 Dec 2016

Scientists unveil role of NOX4 protein as inhibitor of invasion and metastasis of liver tumor cells

Researchers of the TGF-beta and Cancer group of Bellvitge Biomedical Research Institute, in collaboration with King's College London, have unveiled the role of NADPH oxidase NOX4 as an inhibitor of the epithelial-amoeboid transition, a process that contributes to the migration and invasion of tumor cells.

20 Dec 2016

Sirt1 plays key role in regenerating glial progenitor cells after hypoxia-induced brain injury in preemies

Developing brains in newborns have a sizable pool of a certain type of immature progenitor cell that can be expanded and induced to replace cells lost to brain injury.

19 Dec 2016

Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Diamond Blackfan Anemia (DBA) is a condition that is characterized by a failure of the bone marrow to produce red blood cells, congenital abnormalities, and a predisposition to cancer.

17 Dec 2016

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed.

16 Dec 2016