Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Stem cells do help restore heart function – but in a different way

A new study published in the journal Nature shows that stem cells do work well to repair the damaged heart – but in an entirely different manner than was originally supposed. The study shows that stem cells, whether living or dead, when injected into the area of damage in the heart in mice, activate an intense acute inflammation. This triggers the classic wound healing response which finally results in the partial or complete recovery of mechanical function of the injured area.

28 Nov 2019

UCLA scientists discover link between a protein and human blood stem cell self-renewal

UCLA scientists have discovered a link between a protein and the ability of human blood stem cells to self-renew. In a study published today in the journal Nature, the team reports that activating the protein causes blood stem cells to self-renew at least twelvefold in laboratory conditions.

27 Nov 2019

Patients' own stem cells offer a step toward improving motor, sensory function after spinal cord injury

Stem cells derived from a patient's own fat offer a step toward improving - not just stabilizing - motor and sensory function of people with spinal cord injuries, according to early research from Mayo Clinic.

27 Nov 2019

Researchers develop new strategy for treating the most aggressive type of brain cancer

Researchers from the University of São Paulo in Brazil have developed a strategy for treating the most aggressive type of brain cancer in adults that combines a photoactive molecule and a chemotherapeutic agent - both encapsulated in protein-lipid nanoparticles.

27 Nov 2019

LACV-infected cerebral organoids reveal how to protect neurons from virus-induced death

Scientists have determined that La Crosse virus, which can cause inflammation of the brain, or encephalitis, in children, affects brain cells differently depending on their developmental stage.

26 Nov 2019

Stem cells do not take the day off on national holidays

While most of us are stuffing ourselves with turkey and pumpkin pie at home on Thanksgiving Day, the staff at one Cedars-Sinai laboratory will be on the job, feeding stem cells.

26 Nov 2019

Novoheart collaborates with AstraZeneca to develop world’s first human heart-in-a-jar model of heart failure

Novoheart, a global stem cell biotechnology company, is pleased to announce a collaboration with global biopharmaceutical company AstraZeneca, in an effort to develop the world’s first human-specific in vitro, functional model of heart failure with preserved ejection fraction (HFpEF), a common condition especially among the elderly and in women, with the reported prevalence approaching 10% in women over the age of 80 years.

26 Nov 2019

GN Corporation granted Indian patent for novel corneal cell transplantation using nano-composite gel sheet

A novel cell transplantation method to treat corneal endothelial diseases such as bullous keratopathy using a nano-composite gel sheet developed by Japanese scientists was granted Indian patent to GN Corporation (GNC), Japan.

26 Nov 2019

Study reports discovery of tendon stem cells

Being made up of flesh and bone, the human body often suffers injuries due to tendon damage caused by various acute or chronic events. As these damaged tissues recover, scar tissue builds up, causing a slow and often painful recovery.

25 Nov 2019

FDA-approved drug to prevent organ rejection may slow skin aging

The search for youthfulness typically turns to lotions, supplements, serums and diets, but there may soon be a new option joining the fray.

25 Nov 2019

New collaboration aims to provide solutions for patients with hypoplastic left heart syndrome

Mayo Clinic's Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome (HLHS) and Children's of Alabama announce their collaboration within a consortium to provide solutions for patients with hypoplastic left heart syndrome, a rare and complex form of congenital heart disease in which the left side of the heart is severely underdeveloped.

25 Nov 2019

Apoptosis protein API-5 more markedly expressed in chemoresistant triple-negative breast cancer

78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment.

25 Nov 2019

New partnership aims to explore, cultivate innovations in cell and gene therapy

Some patients who have not responded to traditional medicines are now experiencing remarkable recoveries thanks to next-generation immunotherapies. These therapies equip a patient's own immune cells to recognize, target, and destroy cancer cells.

25 Nov 2019

Genes that help intestinal stem cells burn dietary fat may play a role in colon cancer

Two genes that appear to help stem cells in the intestine burn dietary fat may play a role in colon cancer, according to a Rutgers study.

25 Nov 2019

Researchers discover molecular underpinnings of Alexander disease

Scientists have known that genetic mutations leading to the production of a defective protein called GFAP cause Alexander disease (AxD), a debilitating neurodegenerative condition that can present during infancy, adolescence, or adulthood.

21 Nov 2019

Transplanted human brain cells in a mouse brain provide insight into neural circuit formation

The brain cortex, the outside layer of our brain often referred to as grey matter, is one of the most complex structures found in living organisms. It gives us the advanced cognitive abilities that distinguish us from other animals.

21 Nov 2019

Coriell Institute for Medical Research wins $7.7 million NINDS contract

Coriell Institute for Medical Research has been awarded a $7.7 million contract by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health focused on the study of nervous system disorders.

21 Nov 2019

Machine learning successfully replicates cell architecture

A new study reports the use of machine learning to help form complex cell architectures from pluripotent stem cells.

21 Nov 2019

BrainStorm publishes NurOwn ALS Phase 2 randomized clinical trial results in Neurology

BrainStorm Cell Therapeutics Inc., a leader in the development of innovative autologous cellular therapies for highly debilitating neurodegenerative diseases, today announced publication of "NurOwn Phase 2 Randomized Clinical Trial in ALS: Safety, Clinical and BioMarker Results," in the international, peer-reviewed journal Neurology.

20 Nov 2019

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

The first two clinical trials for CRISPR-based treatments for inherited blood disorders have been successful.

20 Nov 2019

Stem Cells News and Research

Further Reading

Stem cells do help restore heart function – but in a different way

UCLA scientists discover link between a protein and human blood stem cell self-renewal

Patients' own stem cells offer a step toward improving motor, sensory function after spinal cord injury

Researchers develop new strategy for treating the most aggressive type of brain cancer

LACV-infected cerebral organoids reveal how to protect neurons from virus-induced death

Stem cells do not take the day off on national holidays

Novoheart collaborates with AstraZeneca to develop world’s first human heart-in-a-jar model of heart failure

GN Corporation granted Indian patent for novel corneal cell transplantation using nano-composite gel sheet

Study reports discovery of tendon stem cells

FDA-approved drug to prevent organ rejection may slow skin aging

New collaboration aims to provide solutions for patients with hypoplastic left heart syndrome

Apoptosis protein API-5 more markedly expressed in chemoresistant triple-negative breast cancer

New partnership aims to explore, cultivate innovations in cell and gene therapy

Genes that help intestinal stem cells burn dietary fat may play a role in colon cancer

Researchers discover molecular underpinnings of Alexander disease

Transplanted human brain cells in a mouse brain provide insight into neural circuit formation

Coriell Institute for Medical Research wins $7.7 million NINDS contract

Machine learning successfully replicates cell architecture

BrainStorm publishes NurOwn ALS Phase 2 randomized clinical trial results in Neurology

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

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