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Le Bonheur and UTHSC sign agreement to obtain genetic information from 25,000 DNA samples

As research into genetic causes of disease began to grow, Le Bonheur Pediatrician-in- Chief Jon McCullers, MD, knew it was time to start building a pediatric DNA biorepository.

13 Mar 2021

Overexpression of signaling protein in heart associated with poor survival after heart attack

About 6.2 million Americans suffer from heart failure, an incurable disease with a staggering mortality rate - some 40 percent of patients die within five years of diagnosis. Heart failure is one form of heart disease, for which new therapies are desperately needed.

13 Mar 2021

Machine learning algorithm predicts risk for suicide attempt

A machine learning algorithm that predicts suicide attempt recently underwent a prospective trial at the institution where it was developed, Vanderbilt University Medical Center.

13 Mar 2021

AI-based assessment of of surgical skills

More than one million operations are performed in Switzerland every year. A surgeon's skill has a direct impact on the outcome of the operation.

13 Mar 2021

Random cellular changes play vital role in longevity beyond genetics and environment

A new model of aging takes into account not only genetics and environmental exposures but also the tiny changes that randomly arise at the cellular level.

13 Mar 2021

Two simple steps that could be taken to tackle the ‘obesity time bomb’

The urgency of tackling the obesity time bomb has been brought to the fore by evidence of the link to an increased risk from COVID-19, says the UK Government's Department of Health and Social Care.

13 Mar 2021

Vital exhaustion may increase risk of heart attack in never married, divorced and widowed men

Men experiencing vital exhaustion are more likely to have a heart attack, according to research presented today at ESC Acute CardioVascular Care 2021, an online scientific congress of the European Society of Cardiology.

13 Mar 2021

Cancer cells may dodge chemotherapy by going into 'active hibernation'

Cancer cells can dodge chemotherapy by entering a state that bears similarity to certain kinds of senescence, a type of "active hibernation" that enables them to weather the stress induced by aggressive treatments aimed at destroying them, according to a new study by scientists at Weill Cornell Medicine.

13 Mar 2021

Neutralizing antibodies induced by COVID-19 vaccines less effective against new variants

SARS-CoV-2, the virus that causes COVID-19, has mutated throughout the pandemic. New variants of the virus have arisen throughout the world, including variants that might possess increased ability to spread or evade the immune system.

13 Mar 2021

Sound sleep plays a crucial role in healing traumatic brain injuries

Sound sleep plays a critical role in healing traumatic brain injury, a new study of military veterans suggests.

13 Mar 2021

SARS-CoV-2 did not change much when it jumped from bats to human hosts

How much did SARS-CoV-2 need to change in order to adapt to its new human host? In a research article published in the open access journal PLOS Biology Oscar MacLean, Spyros Lytras at the University of Glasgow, and colleagues, show that since December 2019 and for the first 11 months of the SARS-CoV-2 pandemic there has been very little 'important' genetic change observed in the hundreds of thousands of sequenced virus genomes.

13 Mar 2021

Study shows link between financial strain, homelessness and severe mental illness

Financial strains like debt or unemployment are significant risk factors for becoming homeless, and even help to explain increased risk of homelessness associated with severe mental illness, reports a study in a supplement to the April issue of Medical Care.

13 Mar 2021

New examination method identifies high-risk plaques likely to cause adverse cardiac events

Researchers at Lund University in Sweden can now show that a new examination method identifies high-risk plaques in the blood vessels surrounding the heart, that cannot be seen solely with traditional angiograms.

12 Mar 2021

To extract more doses per vial, vaccinators put squeeze on FDA to relax vaccine handling advice

President Joe Biden has promised enough covid vaccine to immunize every willing adult by June 1. But right now, the gap between supply and demand is so dramatic that vaccinators are discovering ways to suck the final drops out of each vaccine vial — if federal regulators will let them.

12 Mar 2021

University of Missouri settles lawsuits over knee surgeries involving veterinarian

The University of Missouri has settled a collection of personal injury and false advertising claims over knee surgeries for $16.2 million, in what appears to be one of its largest public payouts in recent years.

12 Mar 2021

Optimizing The Genome Editing Workflow With Microfluidic Technology

A recent grant collaboration, funded by Innovate UK, between Sphere Fluidics, University of Edinburgh, Horizon Discovery, OXGENE, and Twist Bioscience has culminated in a prototype automated microfluidic genome editing platform.

From Fluidic Sciences and Sphere Bio 12 Mar 2021

Optimized nano-micelles can induce efficient genome editing in the mouse brain

The research group of Deputy Principal Research Scientist Dr. Satoshi Uchida (Associate Professor, Kyoto Prefectural University of Medicine) at the Innovation Center of NanoMedicine (Director General: Prof. Kazunori Kataoka, Location: Kawasaki-Japan, Abbreviation: iCONM) reported that optimized nano-micelles can induce efficient genome editing in the mouse brain.

12 Mar 2021

Medicine News and Research

Le Bonheur and UTHSC sign agreement to obtain genetic information from 25,000 DNA samples

Overexpression of signaling protein in heart associated with poor survival after heart attack

Machine learning algorithm predicts risk for suicide attempt

AI-based assessment of of surgical skills

Random cellular changes play vital role in longevity beyond genetics and environment

Two simple steps that could be taken to tackle the ‘obesity time bomb’

Vital exhaustion may increase risk of heart attack in never married, divorced and widowed men

Cancer cells may dodge chemotherapy by going into 'active hibernation'

Neutralizing antibodies induced by COVID-19 vaccines less effective against new variants

Sound sleep plays a crucial role in healing traumatic brain injuries

SARS-CoV-2 did not change much when it jumped from bats to human hosts

Study shows link between financial strain, homelessness and severe mental illness

New examination method identifies high-risk plaques likely to cause adverse cardiac events

To extract more doses per vial, vaccinators put squeeze on FDA to relax vaccine handling advice

University of Missouri settles lawsuits over knee surgeries involving veterinarian

Optimizing The Genome Editing Workflow With Microfluidic Technology

Optimized nano-micelles can induce efficient genome editing in the mouse brain

Living in neighborhoods with high rates of violence and poverty alters gene activity

Optimized nano-micelles can induce efficient genome editing in the mouse brain

Study shows how functional biomaterials rely on interfacial protein layer to transmit signals to living cells

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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