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Inotuzumab ozogamicin study reveals complete remission rates higher than standard therapy for ALL patients

In a randomized Phase III study of the drug inotuzumab ozogamicin, a statistically significant percentage of patients with acute lymphoblastic leukemia (ALL) whose disease had relapsed following standard therapies, qualified for stem cell transplants.

13 Jun 2016

CRP may guide vascular risk assessment in obese

Low C-reactive protein levels may identify obese people who are unlikely to develop cardiovascular complications over subsequent years, show data from the EPIC study.

11 Jun 2016

New method helps speed up bacterial identification

Pinpointing the type of bacteria that are at the root of an infection in clinical samples removed from living tissues, such as blood, urine or joint fluids, to quickly identify the best anti-microbial therapy still poses a formidable challenge.

10 Jun 2016

Researchers discover AF1q protein linked to multiple myeloma, EMD

A group of researchers from the University of Louisville, Japan and Austria is the first to identify a protein, AF1q, associated with multiple myeloma and a condition that occurs in approximately one-fourth of very aggressive multiple myeloma, extramedullary disease or EMD.

10 Jun 2016

Utah researchers find way to use power of protease to destroy budding AIDS virus

When new AIDS virus particles bud from an infected cell, an enzyme named protease activates to help the viruses mature and infect more cells. That's why modern AIDS drugs control the disease by inhibiting protease.

10 Jun 2016

Lack of signaling protein CXCR4 may halt cancer development

Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties.

10 Jun 2016

Enhancing motility of skin cells could help promote wound healing

Skin cells typically spend their entire existence in one place on your body. But Washington State University researchers have seen how the cells will alter the proteins holding them in place and move to repair a wound.

10 Jun 2016

New RNA aptamer can prevent pathogenic protein misfolding

Several diseases occur when mutations cause misfolding of proteins. These include "serpinopathies" which is a group of rare heritable diseases. They are caused by mutations of so-called "serpin" inhibitors of proteolytic enzymes involved in blood coagulation, tissue remodeling, and other important physiological functions.

10 Jun 2016

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

Researchers receive $2.4 million grant to study effects of parenting on behavior of adolescents with FXS

University of Kansas researchers have been awarded a five-year, $2.4 million grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development to study the effects of parenting on the development and behavior of adolescents with Fragile X syndrome, a single-gene disorder that is the most common cause of inherited developmental disability and the leading genetic cause of autism.

9 Jun 2016

Glial cells may play crucial role in addiction-related behaviors

Addiction may be viewed as a disorder of reward learning. To date, addiction research has focused on the molecular adaptations through which memories of exposure to abused substances are encoded and maintained by nerve cells.

9 Jun 2016

Scientists resuscitate efforts to crack KRas protein structures

In the annals of cancer research, a protein known as KRas has become notorious. Part of a family of proteins implicated in 30 percent of cancers, KRas is considered a highly desirable but defiant drug target.

9 Jun 2016

Study provides insights into new pathways to generate universal vaccine against influenza viruses

Diverse antibodies induced in humans by vaccination with an avian influenza virus vaccine may offer broader, more durable protection against multiple strains of influenza than today's vaccines typically provide, according to a study led by Florian Krammer, PhD, Assistant Professor in the Department of Microbiology at the Icahn School of Medicine at Mount Sinai, and Patrick Wilson, PhD, Associate Professor in the Department of Medicine at the University of Chicago.

9 Jun 2016

Whole-exome sequencing can help characterize genetic alterations for commonly used bladder cancer cell lines

Much of basic cancer research is based on studies with cultured cancer cells. However, the usefulness of these studies greatly depends on how accurately these cancer cells grown in a dish represent human tumors.

9 Jun 2016

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

Professor Claudio Luchinat, University of Florence and co-founder of the Magnetic Resonance Center (CERM), speaks to News-Medical about his research in NMR-based metabolomics.

From Bruker BioSpin Group 9 Jun 2016

Study: Mediterranean diet high in vegetable fats does not lead to weight gain compared to low-fat diet

Eating a non-calorie restricted Mediterranean diet high in vegetable fats such as olive oil or nuts does not lead to significant weight gain compared to a low-fat diet, according to a large randomised trial published today in The Lancet Diabetes & Endocrinology journal.

9 Jun 2016

G Protein News and Research

Inotuzumab ozogamicin study reveals complete remission rates higher than standard therapy for ALL patients

CRP may guide vascular risk assessment in obese

New method helps speed up bacterial identification

Researchers discover AF1q protein linked to multiple myeloma, EMD

Utah researchers find way to use power of protease to destroy budding AIDS virus

Lack of signaling protein CXCR4 may halt cancer development

Enhancing motility of skin cells could help promote wound healing

New RNA aptamer can prevent pathogenic protein misfolding

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

Researchers receive $2.4 million grant to study effects of parenting on behavior of adolescents with FXS

Glial cells may play crucial role in addiction-related behaviors

Scientists resuscitate efforts to crack KRas protein structures

Study provides insights into new pathways to generate universal vaccine against influenza viruses

Whole-exome sequencing can help characterize genetic alterations for commonly used bladder cancer cell lines

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

Study: Mediterranean diet high in vegetable fats does not lead to weight gain compared to low-fat diet

Researchers identify promising new compound for targeting triple-negative breast cancer

Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

Understanding DNA scrunching could help develop novel ways to fight infections

New technology can detect KRAS gene mutations, facilitate targeted therapies for lung and colorectal cancers

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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