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Higher insulin dose is positively linked with cancer incidence, study finds

Dr. Yuanjie Mao has led a study published in the Journal of the American Medical Association (JAMA) Oncology looking at the correlation between daily insulin dose and cancer incidence (the number of new cases) among patients with type 1 diabetes, finding that higher insulin dose is positively associated with cancer incidence and that the association is stronger among those with insulin resistance.

29 Jul 2022

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Wake Forest Institute for Regenerative Medicine researchers are using a tumor organoid system to examine the effects of metabolites secreted by bacteria on a specialized immunotherapy – immune checkpoint blockage, a promising cancer treatment development – to determine why some patients don't respond or develop a resistance to the treatment over time.

29 Jul 2022

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

PFAS exposure harms people's health and undermines America's economy

Daily exposure to a class of chemicals used in the production of many household items may lead to cancer, thyroid disease, and childhood obesity, a new study shows.

26 Jul 2022

Potassium-rich diets linked with lower blood pressure in women with high salt intake

Women who eat bananas, avocados and salmon could reduce the negative effects of salt in the diet, according to a study published today in European Heart Journal, a journal of the European Society of Cardiology.

22 Jul 2022

Phase 2a clinical trial describes safety and efficacy of dendrimer nanotherapy in severe COVID-19 patients

A multicenter, randomized, placebo-controlled phase 2a clinical trial has recently been conducted to evaluate the efficacy of a nanotherapeutic compound OP-101 in treating severe COVID-19 patients.

21 Jul 2022

Antibiotics have sex-specific effects on the gut microbiome, preclinical study finds

In a new study, researchers at Cedars-Sinai found that antibiotics have sex-specific effects on the gut microbiome makeup of male and female laboratory rats. The findings, published in the journal Frontiers in Microbiology, could have implications for using the drugs in humans to treat or prevent bacterial infection.

20 Jul 2022

Smoking increases risk of severe COVID-19 outcomes in hospitalized patients

New research assessed the association of smoking with COVID-19 complications.

20 Jul 2022

Hypertension linked to double the risk of severe COVID-19 despite booster vaccination

Having high blood pressure more than doubled a person's risk for hospitalization from an Omicron-variant COVID-19 infection - even despite full vaccination including a booster dose of the COVID-19 vaccines, in an analysis of adults hospitalized with COVID-19 in Los Angeles between December 2021 and April 2022, according to new research published today in Hypertension, an American Heart Association journal.

20 Jul 2022

New score shows improved prediction of mortality after acute kidney injury

Acute kidney injury (AKI) occurs commonly in critically ill patients admitted to the intensive care unit (ICU) and is associated with high morbidity and mortality.

20 Jul 2022

Overstrict salt intake restriction could harm patients with heart failure with preserved ejection

Restricting salt intake is considered a key component of heart failure treatment, but restricting it too much may actually worsen the outcomes for people with a common form of the condition, suggests research published online in the journal Heart.

19 Jul 2022

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming in the live body.

19 Jul 2022

Anti-rejection drug plus immunotherapy could change the lives of kidney transplant patients with cancer

Adding immunotherapy to standard anti-rejection medication could change the lives of thousands of kidney transplant patients with incurable cancer, as new research shows it can reduce this risk of organ rejection and eliminate cancer in a quarter of patients.

18 Jul 2022

Nitazoxanide drug found to be a potent inhibitor of several human coronaviruses

Researchers evaluated the activity of nitazoxanide against human coronaviruses (HCoVs).

18 Jul 2022

Low rate of COVID-19 vaccination among high-risk pregnant women

A new study examines the feelings of pregnant women towards the COVID-19 vaccine.

17 Jul 2022

Novel nanoligomer approach to treat severe COVID-19

Researchers discuss the biodistribution and safety of a novel nanoligomer SBCoV207, which was used to targeted miR-2392 in a murine model.

17 Jul 2022

Study assesses the acceptance of Medicaid insurance among patients diagnosed with cancers

Although there has been a significant increase in the number of U.S. residents insured through Medicaid since the expansion of the Patient Protection and Afforadble Care Act (ACA) in March 2010, the ability of Medicaid-insured patients to access cancer care services has not been well understood.

15 Jul 2022

Kidney News and Research

Higher insulin dose is positively linked with cancer incidence, study finds

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

PFAS exposure harms people's health and undermines America's economy

Potassium-rich diets linked with lower blood pressure in women with high salt intake

Phase 2a clinical trial describes safety and efficacy of dendrimer nanotherapy in severe COVID-19 patients

Antibiotics have sex-specific effects on the gut microbiome, preclinical study finds

Smoking increases risk of severe COVID-19 outcomes in hospitalized patients

Hypertension linked to double the risk of severe COVID-19 despite booster vaccination

New score shows improved prediction of mortality after acute kidney injury

Overstrict salt intake restriction could harm patients with heart failure with preserved ejection

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

Anti-rejection drug plus immunotherapy could change the lives of kidney transplant patients with cancer

Nitazoxanide drug found to be a potent inhibitor of several human coronaviruses

Low rate of COVID-19 vaccination among high-risk pregnant women

Novel nanoligomer approach to treat severe COVID-19

Study assesses the acceptance of Medicaid insurance among patients diagnosed with cancers

New anticoagulant platform holds promise as a revolutionary advancement over the current blood thinners

Y chromosome loss in men can lead to deadly heart failure, research shows

Lumasiran shows efficacy and acceptable safety in patients with PH1 and advanced kidney disease

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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