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Towards imaging biological processes in action at the atomic level

If the key to winning battles is knowing both your enemy and yourself, then scientists are now well on their way toward becoming the Sun Tzus of medicine by taking a giant step toward a priceless advantage - the ability to see the soldiers in action on the battlefield.

21 Dec 2012

New technique to directly image biological structures at atomic levels

Investigators at the Virginia Tech Carilion Research Institute have invented a way to directly image biological structures at their most fundamental level and in their natural habitats. The technique is a major advancement toward the ultimate goal of imaging biological processes in action at the atomic level.

21 Dec 2012

Klerokinesis may prevent some cancers from developing

Researchers at the University of Wisconsin Carbone Cancer Center have discovered a new form of cell division in human cells.

18 Dec 2012

Harmonic generation microscopy can help measure natural age-related changes in skin cells

Wrinkles, dryness, and a translucent and fragile appearance are hallmarks of old skin, caused by the natural aging of skin cells. But while most of us can recognize the signs of lost youth when we peer into the mirror each morning, scientists do not have a standardized way to measure the extent of age damage in skin. Now a group of Taiwanese researchers has used a specialized microscope to peer harmlessly beneath the skin surface to measure natural age-related changes in the sizes of skin cells.

14 Dec 2012

Dementia therapy: an interview with Assoc Prof. Olivier Piguet and Sharon Savage

Dementia is the umbrella term used to describe a number of neurodegenerative brain disorders that cause progressive changes in thinking abilities and behaviour. The kind of deficits experienced by individuals diagnosed with dementia depends on the location and severity of the pathology in the brain.

11 Dec 2012

Intensified chemotherapy can reduce risk of relapse in pediatric patients with B-ALL

Young patients with an aggressive form of leukemia who are likely to relapse after chemotherapy treatment can significantly reduce those odds by receiving additional courses of chemotherapy, suggest the findings of a clinical trial led by investigators at Dana-Farber/Children's Hospital Cancer Center in Boston.

11 Dec 2012

Marijuana legalization in 2 states comes under microscope

The New York Times reports the Justice Department and senior White House officials are debating legal action against Colorado and Washington, which could undermine voter-approved initiatives. Meanwhile, a USA Today/Gallup Poll shows Americans are divided on decriminalization efforts but believe the federal government should not intervene after states vote to take that step.

7 Dec 2012

Novel organic metamaterial holds promise for drug delivery

A bit reminiscent of the Terminator T-1000, a new material created by Cornell researchers is so soft that it can flow like a liquid and then, strangely, return to its original shape.

7 Dec 2012

Microarray technology provides comprehensive result during prenatal care of women

A new method for detecting abnormalities in unborn children is providing physicians with more information to analyze the results than conventional, microscopic testing, according to two George Washington University researchers.

7 Dec 2012

Paper reveals how 'kinase' is distributed across membranes

Using a super-resolution fluorescent microscope, Australian medical scientists are a step closer to understanding why and how human immune cells decide to activate or not, thus enabling or preventing disease taking hold in the body.

5 Dec 2012

Bruker secures major orders for its new SP9900+ 3D Optical Microscope

Bruker announced today that it has already received more than $7 million in orders for its new Bruker SP9900+ high-throughput high density interconnect (HDI) substrate metrology system, and has begun shipping the product in volume.

From Bruker Nano Surfaces and Metrology 3 Dec 2012

Microscope system designed to acquire very low-light bioluminescence images introduced in North America by Olympus America

A benchtop commercial microscope system designed to acquire very low-light bioluminescence images has now been introduced in North America by Olympus America. The LV200 stand-alone microscope system is already being used to capture images of living cells and tissues by researchers in Europe and Japan.

From Evident Corporation - Life Sciences 29 Nov 2012

Study broadens understanding of how cells regulate X chromosome inactivation

In a paper published in the Nov. 21 issue of Cell, a team led by Mauro Calabrese, a postdoctoral fellow at the University of North Carolina in the lab of Terry Magnuson, chair of the department of genetics and member of the UNC Lineberger Comprehensive Cancer Center, broadens the understanding of how cells regulate silencing of the X chromosome in a process known as X-inactivation.

28 Nov 2012

Bruker combines nanoscale AFM zoom capabilities with high-throughput 3D optical microscopy

Bruker announced today at the 2012 Materials Research Society (MRS) Fall Meeting the release of the unique NanoLens Atomic Force Microscope (AFM) accessory for ContourGT 3D optical microscopes.

From Bruker Nano Surfaces and Metrology 26 Nov 2012

New method can minimize number of missed cervical cancer cases

Routine smear tests have considerably reduced the number of cases of cervical cancer, but despite intensive screening 250 women in Sweden still die from the disease every year. Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, have developed new methods of minimising the number of missed cases and making diagnosis more reliable.

26 Nov 2012

Major advance in understanding how flu viruses replicate within infected cells

Scientists at The Scripps Research Institute (TSRI) have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy techniques to "see" one of influenza's essential protein complexes in unprecedented detail. The images generated in the study show flu virus proteins in the act of self-replication, highlighting the virus's vulnerabilities that are sure to be of interest to drug developers.

23 Nov 2012

New research provides unprecedented clarity to aging process

For the first time, scientists at Fred Hutchinson Cancer Research Center have defined key events that take place early in the process of cellular aging.

23 Nov 2012

Breakthrough in heart research

Breakthrough in heart research: The research team from Professor Katja Schenke-Layland of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart has discovered cell surface markers that enable the identification and isolation of living functional cardiovascular progenitor cells (CPCs).

22 Nov 2012

Obesity and oxidative stress: an interview with Dr Elizabeth New

Even though oxygen is essential for us to live, it can react with other compounds in the body to produce molecules called free radicals, which are highly reactive and damaging.

22 Nov 2012

GW researcher gets NCI grant to study behavior of parasitic worm in bile duct cancer

Paul Brindley, Ph.D., professor of microbiology, immunology, and tropical medicine at the George Washington University School of Medicine and Health Sciences, was the recipient of a $1.7 million grant from the National Cancer Institute to study the behavior of a parasitic worm, rampant in Southeast Asia, known to cause infections that contribute to liver cancer.

16 Nov 2012

Microscope News and Research

Towards imaging biological processes in action at the atomic level

New technique to directly image biological structures at atomic levels

Klerokinesis may prevent some cancers from developing

Harmonic generation microscopy can help measure natural age-related changes in skin cells

Dementia therapy: an interview with Assoc Prof. Olivier Piguet and Sharon Savage

Intensified chemotherapy can reduce risk of relapse in pediatric patients with B-ALL

Marijuana legalization in 2 states comes under microscope

Novel organic metamaterial holds promise for drug delivery

Microarray technology provides comprehensive result during prenatal care of women

Paper reveals how 'kinase' is distributed across membranes

Bruker secures major orders for its new SP9900+ 3D Optical Microscope

Microscope system designed to acquire very low-light bioluminescence images introduced in North America by Olympus America

Study broadens understanding of how cells regulate X chromosome inactivation

Bruker combines nanoscale AFM zoom capabilities with high-throughput 3D optical microscopy

New method can minimize number of missed cervical cancer cases

Major advance in understanding how flu viruses replicate within infected cells

New research provides unprecedented clarity to aging process

Breakthrough in heart research

Obesity and oxidative stress: an interview with Dr Elizabeth New

GW researcher gets NCI grant to study behavior of parasitic worm in bile duct cancer

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