Oxidative Stress News and Research

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Oxidative Stress is a condition in which antioxidant levels are lower than normal. Antioxidant levels are usually measured in blood plasma.

Researchers look at role of oxidative stress in human diseases

Oxidative stress is known to underlie many human diseases including atherosclerosis, Parkinson's disease and Alzheimer's disease.

17 Sep 2007

Proteins Nox1 and Nox2 play important role in amyotrophic lateral sclerosis

University of Iowa researchers investigating the basic biology of cell signaling have made a discovery that may have therapeutic implications for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.

13 Sep 2007

Link between nicotine and atherosclerosis

It's well known that smoking cigarettes increases risk for a host of serious health problems from cancer to heart disease. Now a new study from Weill Cornell Medical College in New York City looks at how they do their dirty work by contributing to atherosclerosis, or hardening of the arteries. The evidence points to nicotine, the addictive chemical in cigarettes.

11 Sep 2007

Potential new drug target for preventing postmenopausal bone loss

Scientists have discovered new information about an immune pathway in mice that explains how oxidative stress that results from acute estrogen deficiency leads to the loss of bone.

11 Sep 2007

Smoking ups Alzheimer's risk by 50%

According to a new Dutch study people over the age of 55 who are smokers put themselves at a far greater risk of developing dementia than people who do not smoke.

5 Sep 2007

Smoking and Alzheimer's disease

People who smoke are more likely to develop Alzheimer's disease or dementia than nonsmokers or those who smoked in the past, according to a study published in the September 4, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.

4 Sep 2007

Discovery may lead to new class of diabetes drugs

A multidisciplinary team led by researchers at the University of California, San Diego has determined the structure of a protein found in cells that shows potential as a target for the development of new drugs to treat diabetes.

30 Aug 2007

Binding up iron in the brain to combat Parkinson's and Alzheimer's

Duke University chemists are developing ways to bind up iron in the brain to combat the neurological devastation of Parkinson's and Alzheimer's diseases.

24 Aug 2007

Reported failure of vitamin E to prevent heart attacks may be due to underdosing

The findings, published early online in Free Radical Biology and Medicine, suggest that these earlier studies all had a fundamental flaw the doses used werent high enough to have a significant antioxidant effect.

24 Aug 2007

Air pollution linked to poor lung function growth in children

Children who are chronically exposed to higher levels of air pollution show marked deficiencies in lung growth and function, and not just short-term breathing problems, according to researchers in Mexico.

17 Aug 2007

Antioxidant overload

Despite the popular notion that antioxidants, such as vitamins C and E, offer health-promoting benefits by protecting against damaging free radicals, a new study in the August 10 issue of the journal Cell reveals that, in fact, balance is the key.

12 Aug 2007

Connection between reduced glutathione and heart failure

Antioxidants are widely considered an important defense against heart disease, but University of Utah researchers have found excessive levels of one antioxidant - reduced glutathione - actually may contribute to the disease.

12 Aug 2007

Potential new ways to prevent smoking-related cellular damage

In the current issue of PLoS One, researchers show how a poorly understood and previously unsuspected mechanism may be the key to understanding how life-style associated forms of oxidative stress, such as exposure to cigarette smoke, damage cells in the lungs.

7 Aug 2007

Neuroprotectin D1 protects retinal pigment epithelial (RPE) cells

Two papers to be published in the Early Edition online of the Proceedings of the National Academy of Sciences (PNAS) the week of July 30-August 3, 2007 report findings that demonstrate that neuroprotectin D1 (NPD1) protects against damage to retinal pigment epithelial (RPE) cells and identifies an important trigger for its production and novel molecular mechanisms that support vision.

1 Aug 2007

Air pollution has a role to play in atherosclerosis

Should we be watching our exposure to airborne pollution as well as our cholesterol levels?

26 Jul 2007

Reducing insulin signaling in the brain can prolong lifespan

One route to a long and healthy life may be establishing the right balance in insulin signaling between the brain and the rest of the body, according to new research from Children's Hospital Boston.

20 Jul 2007

Orange juice healthy for diabetics

Orange juice, despite its high caloric load of sugars, appears to be a healthy food for diabetics due to its mother lode of flavonoids, a study by endocrinologists at the University at Buffalo has shown.

18 Jul 2007

Early exposure to iron and later exposure to herbicide paraquat may accelerate age-related neurodegeneration

Exposure to iron during the first weeks of life in combination with exposure later in life to a common herbicide may contribute to the subsequent degeneration of brain cells associated with the onset of Parkinson's disease (PD), according to a new study in mice.

28 Jun 2007

Role of environmental factors in the development of Parkinson's disease

Scientists at the Buck Institute for Age Research have shown that combining two environmental toxic substances accelerated age-related degeneration in neurons associated with Parkinson's disease (PD) in mice.

27 Jun 2007

Link between levels of urate in the blood and risk of Parkinson's disease

In a new, large-scale, prospective study exploring the link between levels of urate in the blood and risk of Parkinson's disease, researchers from the Harvard School of Public Health (HSPH) have found that high levels of urate are strongly associated with a reduced risk of the disease.

23 Jun 2007