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New tool can help researchers split and reassemble proteins

Researchers have developed a computational tool that makes it possible to split proteins and then restore them to functionality.

2 Oct 2018

Newly discovered protein shown to cause amyloid-beta plaques in Alzheimer's

Scientists have discovered that a potassium channel called KCNB1 can trigger the formation of amyloid-beta plaques seen in Alzheimer's disease.

2 Oct 2018

Immune protein 'flutters' like a butterfly in search of viruses, finds study

Researchers at Rutgers Robert Wood Johnson Medical School have identified an important step in the process that allows our bodies to fight viruses.

2 Oct 2018

Nanoparticles show promise in treatment for triple-negative breast cancer, finds study

Approximately 10-20 percent of diagnosed breast cancers are found to be triple-negative, meaning the breast cancer cells test negative for estrogen and progesterone receptors as well as HER2 receptors, genes that can play a role in the development of breast cancer.

1 Oct 2018

Study finds disease-causing mutation in French-Canadians

A team of Canadian scientists, including researchers at the Montreal Neurological Institute and Hospital has discovered the first French-Canadian founder mutation gene linked to synucleinopathies, a group of neurodegenerative diseases that includes Parkinson's disease, dementia with Lewy-Bodies and multiple system atrophy

1 Oct 2018

Study using DFMO shows positive results for children with high risk neuroblastoma

A paper published September 27 in Scientific Reports shows the positive results of a phase II clinical trial using the oral medication DFMO to prevent relapse in children with High Risk Neuroblastoma.

1 Oct 2018

New, more efficient method for generating brain stem cells in the lab

In two newly published papers, a scientific team at Case Western Reserve University School of Medicine reports on the discovery and implementation of a new, more efficient method for generating an important brain stem cell in the laboratory.

1 Oct 2018

Researchers caution that expediting HLH treatment may miss underlying cancers

Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis report in a new study that extra care should be taken to ensure an HLH diagnosis doesn't obscure possible underlying cancers.

1 Oct 2018

Genetic variants reveal novel therapeutic targets for chronic kidney disease

The kidney does more than double or even triple duty compared to other organs - it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones.

1 Oct 2018

Why patients with ALL relapse after CAR-T cell therapy

Researchers have made a new discovery about a rare mechanism that triggers the relapse of acute lymphoblastic leukemia (ALL) after CAR T cell therapy.

1 Oct 2018

Why patients with ALL relapse after CAR-T cell therapy

Researchers have made a new discovery about a rare mechanism that triggers the relapse of acute lymphoblastic leukemia (ALL) after CAR T cell therapy.

1 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

HyFly research project aims to break chains of infection and prevent pandemics

Global air travel isn't restricted to people and goods - infectious agents, too, can make their way on board as unwelcome passengers and travel great distances within a matter of hours.

1 Oct 2018

Gangrene-causing bacteria show promise as cancer treatment

Researchers have found that the bacteria responsible for causing gangrene could also be used to treat patients with certain cancers.

1 Oct 2018

New analysis confirms value of minimal residual disease as prognostic indicator in multiple myeloma

Adaptive Biotechnologies today announced that Blood, the Journal of the American Society of Hematology, published online an analysis of patient samples from the Intergroupe Francophone du Myéloma 2009 trial.

1 Oct 2018

Xenex LightStrike Germ-Zapping Robots help reduce infection rates at Martin Medical Center

Patient safety is a top priority at Martin Medical Center, which recently announced that it has seen a significant reduction in its Clostridium difficile (C.diff) infection rates since adopting Xenex LightStrike Germ-Zapping Robots as its environmental standard of care.

1 Oct 2018

International conference features cutting-edge research studies on cancer immunotherapy

The Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, to be held in New York, Sept. 30-Oct. 3, will feature cutting-edge research studies from around the world that endeavor to answer urgent questions in the field of cancer immunotherapy to advance progress more rapidly for patients.

1 Oct 2018

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Today the U.S. Food and Drug Administration permitted marketing of ClonoSEQ assay, a next generation sequencing-based test for minimal residual disease in patients with acute lymphoblastic leukemiaor multiple myeloma. MRD is a measure of the amount of cancer cells remaining in a person's bone marrow.

30 Sep 2018

$Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors$

Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors

A phase I clinical trial investigating the use of bacterial Clostridium novyi-NT spores as an injectable monotherapy had manageable toxicities and showed early clinical efficacy in patients with treatment-refractory solid tumor malignancies, according to data presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

New EU-funded project trials novel type of graft for replacement of aortic valves

The EU-funded project ARISE is trialing a novel type of graft for the replacement of aortic valves: it is using donated human heart valves that have been stripped of the donor’s cells to appease the recipient’s immune system.

29 Sep 2018

B Cell News and Research

New tool can help researchers split and reassemble proteins

Newly discovered protein shown to cause amyloid-beta plaques in Alzheimer's

Immune protein 'flutters' like a butterfly in search of viruses, finds study

Nanoparticles show promise in treatment for triple-negative breast cancer, finds study

Study finds disease-causing mutation in French-Canadians

Study using DFMO shows positive results for children with high risk neuroblastoma

New, more efficient method for generating brain stem cells in the lab

Researchers caution that expediting HLH treatment may miss underlying cancers

Genetic variants reveal novel therapeutic targets for chronic kidney disease

Why patients with ALL relapse after CAR-T cell therapy

Why patients with ALL relapse after CAR-T cell therapy

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

HyFly research project aims to break chains of infection and prevent pandemics

Gangrene-causing bacteria show promise as cancer treatment

New analysis confirms value of minimal residual disease as prognostic indicator in multiple myeloma

Xenex LightStrike Germ-Zapping Robots help reduce infection rates at Martin Medical Center

International conference features cutting-edge research studies on cancer immunotherapy

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors

New EU-funded project trials novel type of graft for replacement of aortic valves

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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