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New naturally occurring antibiotic found effective against Mycobacterium tuberculosis

A naturally occurring antibiotic called kanglemycin A is effective against Mycobacterium tuberculosis, the bacteria that cause tuberculosis, even in drug-resistant strains, according to an international team of researchers who used chemistry, molecular biology, microbiology, and X-ray crystallography to show how the compound maintains its activity.

21 Sep 2018

Salk Institute researchers uncover molecular structure of RNA-based CRISPR system

Over the past several years, CRISPR-Cas9 has moved beyond the lab bench and into the public zeitgeist. This gene-editing tool CRISPR-Cas9 holds promise for correcting defects inside individual cells and potentially healing or preventing many human ailments.

20 Sep 2018

Study reveals promising new drug candidate to treat acute renal failure

A protein produced by the human body appears to be a promising new drug candidate to treat conditions that lead to acute renal failure. This is shown by a study conducted at São Paulo State University in São José do Rio Preto, Brazil.

20 Sep 2018

Novel mathematical approach uncovers existence of unsuspected biological cycles

A novel mathematical approach has uncovered that some animal cells have robust 12-hour cycles of genetic activity, in addition to circadian or 24-hour cycles.

20 Sep 2018

Body organs undergo structural changes in response to diet

Body organs such as the intestine and ovaries undergo structural changes in response to dietary nutrients that can have lasting impacts on metabolism, as well as cancer susceptibility, according to Carnegie's Rebecca Obniski, Matthew Sieber, and Allan Spradling.

20 Sep 2018

Sea squirt model reveals key molecules in dopaminergic neuron differentiation

The human brain is exceedingly complex, consisting of various regions with particular functions and approximately 100 billion neurons. This complexity has presented a major challenge in understanding this organ and how it develops, particularly in view of the ethical issues associated with research on humans.

20 Sep 2018

Scientists predict how well the body will fight lung cancer by analyzing immune cell shapes

Researchers at Case Western Reserve University have discovered how to quickly and accurately predict which lung cancer patients will benefit from chemotherapy by analyzing how immune cells the body sends out to fight the disease are arranged.

20 Sep 2018

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading of the disease, one of the first known examples of researchers doing so.

20 Sep 2018

Neurons in the human brain can encode numerical information

How do we know if we're looking at three apples or four? Researchers at the Universities of Bonn and Tübingen are now one step closer to answering this question.

20 Sep 2018

Finding epigenetic signature appears to predict inflammation risk in serious type of IBD

With an estimated 1.6 million people in the U.S. dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective.

20 Sep 2018

Scientists find way to boost efficacy of powerful antimalarial drug with anti-cancer medicines

Scientists have found a way to boost the efficacy of the world's most powerful antimalarial drug with the help of chemotherapy medicines, according to new research published in the journal Nature Communications.

20 Sep 2018

Innovative approach for developing vaccine against most prevalent human malaria parasite

A novel study indicates promising avenues in an innovative approach for developing a vaccine against Plasmodium vivax, the most prevalent human malaria parasite outside sub-Saharan Africa.

20 Sep 2018

Progenitor cells for human bone and cartilage have been identified

Research published today describes for the first time the identification of human skeletal stem cells. The discovery may enable the development of novel therapeutic strategies for diseases that cause skeletal degeneration.

20 Sep 2018

Logos Biosystems Introduces the New CELENA X High Content Imaging System

Logos Biosystems has released the all-new CELENA® X integrated High Content Imaging System, providing the complete solution for rapid high content image acquisition and quantitative analysis.

From Logos Biosystems 20 Sep 2018

Study could allow doctors to screen patients at risk from Aspergillus

Scientists at The University of Manchester have discovered a genetic mutation in humans linked to a 17-fold increase in the amount of dangerous fungal spores in the lungs.

20 Sep 2018

Cell Medica successfully doses first patient with CMD-501 targeting pediatric neuroblastoma

Cell Medica announces the treatment of the first patient world-wide to receive CMD-501, an autologous CAR-NKT therapy targeting pediatric neuroblastoma

20 Sep 2018

New guidance for treatment of bone loss in hematologic stem cell transplant Recipients

Hematopoietic stem cell transplantation is the treatment of choice for many patients with malignant and non-malignant hematological diseases, such as leukemia and multiple myeloma. The success of recent advances in such transplantation techniques and supportive care measures, has led to greater numbers of long-term HSCT survivors.

20 Sep 2018

UK and European research collaborations receive vote of confidence by three major cancer charities

UK and European research collaborations in cancer research have received a vote of confidence by three major cancer charities, with an announcement today of approximately £30 million into six international projects.

20 Sep 2018

Scientists better understand influenza virus and how it spreads

The seasonal flu is caused by different subtypes of Influenza A virus and typically leads to the death of half a million people each year.

20 Sep 2018

Geroscience takes center stage in Journal of the American Medical Association

Geroscience--the burgeoning research field that focuses on the genetic, molecular, and cellular mechanisms that make aging a major risk factor for most chronic diseases as we age--takes center stage in the Journal of the American Medical Association, the world's most widely circulated medical journal.

20 Sep 2018

B Cell News and Research

New naturally occurring antibiotic found effective against Mycobacterium tuberculosis

Salk Institute researchers uncover molecular structure of RNA-based CRISPR system

Study reveals promising new drug candidate to treat acute renal failure

Novel mathematical approach uncovers existence of unsuspected biological cycles

Body organs undergo structural changes in response to diet

Sea squirt model reveals key molecules in dopaminergic neuron differentiation

Scientists predict how well the body will fight lung cancer by analyzing immune cell shapes

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

Neurons in the human brain can encode numerical information

Finding epigenetic signature appears to predict inflammation risk in serious type of IBD

Scientists find way to boost efficacy of powerful antimalarial drug with anti-cancer medicines

Innovative approach for developing vaccine against most prevalent human malaria parasite

Progenitor cells for human bone and cartilage have been identified

Logos Biosystems Introduces the New CELENA X High Content Imaging System

Study could allow doctors to screen patients at risk from Aspergillus

Cell Medica successfully doses first patient with CMD-501 targeting pediatric neuroblastoma

New guidance for treatment of bone loss in hematologic stem cell transplant Recipients

UK and European research collaborations receive vote of confidence by three major cancer charities

Scientists better understand influenza virus and how it spreads

Geroscience takes center stage in Journal of the American Medical Association

Immunology eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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