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Study unveils mechanisms behind antigenic variation in pathogens

A new study by LMU and Helmholtz Munich shows how pathogens control changes in their cell surface to evade the immune system.

14 Mar 2025

Semi-synthetic bile acid could be a promising therapeutic option for TH17-mediated intestinal diseases

A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation.

14 Mar 2025

Current state and future prospects of artificial ligaments for treating ACL injuries

Anterior cruciate ligament (ACL) injuries are common, especially among athletes. Each year, over 400 000 ACL reconstruction (ACLR) surgeries are carried out globally.

14 Mar 2025

Groundbreaking stem cell therapy trial for Alzheimer's disease underway at UTHealth Houston

A stem cell therapy trial aimed at reducing neuroinflammation in patients with presymptomatic Alzheimer's disease is underway at UTHealth Houston.

14 Mar 2025

Combination of RAS inhibition and immunotherapy provides breakthrough for pancreatic cancer

Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer at bay in preclinical models for significantly longer than the same targeted therapy by itself, according to researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

14 Mar 2025

Pitt study uncovers a novel trigger of deadly form of ovarian cancer

Researchers at the University of Pittsburgh have identified a novel trigger of a deadly form of ovarian cancer: a subset of progenitor cells that reside in fallopian tube supportive tissue, or stroma.

14 Mar 2025

New laboratory tool identifies viruses to combat Staphylococcus aureus

A newly developed laboratory tool can, within hours, help to identify specific viruses which can be used to destroy variants of the dangerous pathogenic bacteria Staphylococcus aureus.

14 Mar 2025

New research aims to unravel genetic mysteries of polycystic kidney disease

Polycystic kidney disease (PKD), a family of genetic disorders that causes clusters of cysts to form on the kidney, is among the most common genetic disorders, affecting some 500,000 people in the United States.

14 Mar 2025

New therapeutic approach shows promise for pediatric high-grade gliomas

Brain tumors remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than 18 months after diagnosis and limited treatment options.

14 Mar 2025

What can you do with a BioAFM instrument?

Even more answers to help understand how BioAFM can be used!

From Bruker BioAFM 14 Mar 2025

WEHI team makes major strides in the fight against Parkinson's disease

WEHI researchers have made a huge leap forward in the fight against Parkinson's disease, solving a decades-long mystery that paves the way for development of new drugs to treat the condition.

14 Mar 2025

CityUHK leads groundbreaking project to develop new platform for early cancer detection

Cancer continues to be a leading cause of mortality worldwide, highlighting the urgent need to develop more advanced, efficient, and early detection methods.

13 Mar 2025

New lab-grown pig retinal organoids could aid stem cell-based vision therapy

Inside the human eye, the retina is made up of several types of cells, including the light-sensing photoreceptors that initiate the cascade of events that lead to vision.

13 Mar 2025

Parkinson’s disease will affect 25 million people by 2050, study warns

Global Parkinson’s disease cases are projected to more than double to 25.2 million by 2050, driven largely by aging populations and socio-demographic factors. The sharpest increases are expected in Sub-Saharan Africa and South Asia, with men disproportionately affected.

13 Mar 2025

Scientists reveal how Epstein-Barr virus reactivation triggers MIS-C in children

Scientists reveal that reactivation of Epstein-Barr virus (EBV), driven by TGFβ-induced immune suppression, is a key driver of multisystem inflammatory syndrome in children (MIS-C) following COVID-19. Blocking TGFβ may offer a potential new treatment for this life-threatening condition.

13 Mar 2025

Targeting MARCO enhances cancer immunotherapy effectiveness

Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor with collagenous structure, or MARCO.

13 Mar 2025

Already approved drug avapritinib shows promise in treating high-grade gliomas

High-grade glioma, an aggressive form of pediatric and adult brain cancer, is challenging to treat given the tumor location, incidence of recurrence and difficulty for drugs to cross the blood-brain barrier.

13 Mar 2025

Combination immunotherapy improves treatment response for head and neck cancer

Researchers conducting a clinical trial of immunotherapy drugs for people with head and neck squamous cell carcinomas (HNSCCs) found that patients responded better to a combination of two immunotherapies than patients who received just one immunotherapy drug.

13 Mar 2025

MIT engineers develop efficient method to convert skin cells into neurons

Converting one type of cell to another - for example, a skin cell to a neuron - can be done through a process that requires the skin cell to be induced into a "pluripotent" stem cell, then differentiated into a neuron.

13 Mar 2025

Diterpenes show promise in regenerating neurons after brain injury

Researchers from the University of Seville and the University of Cadiz, coordinated by the professors of Physiology Pedro Núñez-Abades and Carmen Castro, have demonstrated that the use of diterpenes facilitates repopulation with new neurons in brain regions damaged by traumatic injuries.

13 Mar 2025