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New book explores research into viral nanoparticles

Viruses that attack plants, insects, mammals and bacteria are proving effective platforms for delivering medicines and imaging chemicals to specific cells in the body, as building blocks for tiny battery electrodes and computer data storage devices, and other nanotechnologies.

1 Jul 2011

Two defective genes may cause telomere elongations in cancer cells: Study

Scientists at Johns Hopkins have provided more clues to one of the least understood phenomena in some cancers: why the "ends caps" of cellular DNA, called telomeres, lengthen instead of shorten.

1 Jul 2011

Conventional Estrogen Receptor measurement methods may result in 10-20% false negative rate

A team of Yale Cancer Center researchers has confirmed that between 10-20% of breast cancers classified as Estrogen Receptor (ER) negative are really positive. Understanding when and why breast cancers may be misclassified has important implications for treatment and outcomes for women diagnosed with breast cancer. Its findings are published online in the June 28 Journal of Clinical Oncology.

28 Jun 2011

Los Alamos National Lab scientists win three R&D Magazine's 2011 awards

Los Alamos National Laboratory scientists have won three of R&D Magazine's 2011 R&D100 Awards. Recognized as the "Oscars of Invention" by the Chicago Tribune, these awards honor the top 100 proven technological advances of the past year.

23 Jun 2011

Fluorescent signature discovery helps identify parathyroid glands during endocrine surgery

The parathyroid glands - four small organs the size of grains of rice located at the back of the throat - glow with a natural fluorescence in the near infrared region of the spectrum.

21 Jun 2011

Researchers uncover protein structural clues associated to PD

Researchers at the Keck School of Medicine of the University of Southern California (USC) have uncovered structural clues about the protein linked to Parkinson's disease (PD), which ultimately could lead to finding a cure for the degenerative neurological disorder.

18 Jun 2011

Ventana Medical receives FDA approval for new breast cancer genetic test

The U.S. Food and Drug Administration today approved a new genetic test that will help health care professionals determine if women with breast cancer are HER2-positive and, therefore, candidates for Herceptin, a commonly used breast cancer treatment.

15 Jun 2011

Synaptophysin controls replacement of vesicles

A University of Wisconsin-Madison research team has solved a 25-year mystery that may lead to better treatments for people with learning deficits and mental retardation.

9 Jun 2011

Novel FRET biosensor allows measurement of intraorganellar glutathione potentials in living cells

In work published in the June 2011 issue of Experimental Biology and Medicine, Kolossov, Spring and their co-investigators - a multidisciplinary team within the Institute for Genomic Biology at the University of Illinois - have transferred the concept of redox-sensitive Green Fluorescent Proteins (GFPs) to a quantitative F-rster resonance energy transfer (FRET) imaging platform.

8 Jun 2011

Super microscopes help scientists identify exact molecular 'switch' that spurs T-cells into action

Using the only microscope of its kind in Australia, medical scientists have been able for the first time to see the inner workings of T-cells, the front-line troops that alert our immune system to go on the defensive against germs and other invaders in our bloodstream.

6 Jun 2011

New understanding of muscle growth and repair

Revealing another part of the story of muscle development, Johns Hopkins researchers have shown how the cytoskeleton from one muscle cell builds finger-like projections that invade into another muscle cell’s territory, eventually forcing the cells to combine.

5 Jun 2011

Scientists use super microscope to pinpoint body’s immunity ‘switch’

5 Jun 2011

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Atherosclerosis is the most common cause of cardiovascular disease, and results from chronic inflammation of arterial vessel walls. An international collaboration led by Professor Christian Weber of Ludwig-Maximilians-Universität (LMU) in Munich and Privatdozentin Alma Zernecke of Würzburg University now shows that dendritic cells stimulate this process by derailing a mechanism that normally acts as a brake on immune reactions.

4 Jun 2011

MreB protein molecules assemble into larger units in bacterial cell wall

Almost all bacteria owe their structure to an outer cell wall that interacts closely with the supporting MreB protein inside the cell. As scientists at the Max Planck Institute for Biochemistry and at the French INRA now show, MreB molecules assemble into larger units, but not - as previously believed - into continuous helical structures.

4 Jun 2011

Insight into understanding of normal muscle growth

Revealing another part of the story of muscle development, Johns Hopkins researchers have shown how the cytoskeleton from one muscle cell builds finger-like projections that invade into another muscle cell's territory, eventually forcing the cells to combine.

4 Jun 2011

New imaging method using fluorescent nanotubes can peer clearly into living mouse's innards

Developing drugs to combat or cure human disease often involves a phase of testing with mice, so being able to peer clearly into a living mouse's innards has real value.

30 May 2011

UBC scientists to initiate $4.7M pan-Canadian clinical trial in oral squamous cell cancers

Researchers from the University of British Columbia's Faculties of Medicine, Science and Dentistry are leading a $4.7-million pan-Canadian clinical trial aimed at improving outcomes for patients undergoing surgery for oral squamous cell cancers.

30 May 2011

Pan-Canadian surgical study offers new hope for patients with early-stage oral cancer

Currently, about 30 per cent of patients who receive oral surgery have their cancer recur. But a new, Canada-wide surgical trial using a new approach to remove tumours and pre-cancerous cells from the mouths of those diagnosed with early-stage oral cancer offers new hope for patients.

27 May 2011

Insight into new prion formation

Unlocking the mechanisms that cause neurodegenerative prion diseases may require a genetic key, suggest new findings reported by University of Illinois at Chicago distinguished professor of biological sciences Susan Liebman.

27 May 2011

Nanoscopic findings may lead to new experimental methods for early multiple sclerosis diagnosis

Laboratory studies by chemical engineers at UC Santa Barbara may lead to new experimental methods for early detection and diagnosis -- and to possible treatments -- for pathological tissues that are precursors to multiple sclerosis and similar diseases.

24 May 2011

Fluorescence News and Research

New book explores research into viral nanoparticles

Two defective genes may cause telomere elongations in cancer cells: Study

Conventional Estrogen Receptor measurement methods may result in 10-20% false negative rate

Los Alamos National Lab scientists win three R&D Magazine's 2011 awards

Fluorescent signature discovery helps identify parathyroid glands during endocrine surgery

Researchers uncover protein structural clues associated to PD

Ventana Medical receives FDA approval for new breast cancer genetic test

Synaptophysin controls replacement of vesicles

Novel FRET biosensor allows measurement of intraorganellar glutathione potentials in living cells

Super microscopes help scientists identify exact molecular 'switch' that spurs T-cells into action

New understanding of muscle growth and repair

Scientists use super microscope to pinpoint body’s immunity ‘switch’

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

MreB protein molecules assemble into larger units in bacterial cell wall

Insight into understanding of normal muscle growth

New imaging method using fluorescent nanotubes can peer clearly into living mouse's innards

UBC scientists to initiate $4.7M pan-Canadian clinical trial in oral squamous cell cancers

Pan-Canadian surgical study offers new hope for patients with early-stage oral cancer

Insight into new prion formation

Nanoscopic findings may lead to new experimental methods for early multiple sclerosis diagnosis

Choosing the right benchtop fluorescence microscope: A practical buyer's guide eBook

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