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New study suggests broad neutralizing antibody could provide three years of COVID protection

In a recent article published in the journal Science Translational Medicine, researchers showed that a novel, lab-engineered monoclonal antibody (mAb), adintrevimab conferred up to 50% protection against symptomatic coronavirus disease 2019 (COVID-19). Furthermore, it demonstrated this exceptional efficacy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–naïve individuals even at titers as low as 1:30.

27 Mar 2023

Epigenome reprogramming after SARS-CoV-2 infection

Researchers performed a 3D evaluation of SARS-CoV-2 infected human cells.

27 Mar 2023

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

The breast tumors of Asian, Black and white women have very different cellular, microbial and genomic features that could potentially be used to personalize care or predict disease progression, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center.

27 Mar 2023

New statement suggests next steps to interpret incidentally identified gene variants related to heart disease

Increasing use of genetic testing means people may discover they have a gene variant associated with some types of cardiovascular disease (CVD).

27 Mar 2023

New technology can rapidly analyze the metabolic state of lipids in cells

Professor Itaru Hamachi, Lecturer Tomonori Tamura, and Assistant Professor Masaki Tsuchiya of Kyoto University have developed a new technology called O-ClickFC (Organelle-selective click labeling with flow cytometry), which can, at a very high speed, analyze the metabolic state of lipids in cells.

27 Mar 2023

Microbes living in the human body may be acting as a reservoir for antibiotic resistance

The community of microbes living in and on our bodies may be acting as a reservoir for antibiotic resistance, according to new research from the Earlham Institute and Quadram Institute in Norwich.

27 Mar 2023

Monocytes may be a stable reservoir of HIV in patients taking antiretroviral therapy

To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.

27 Mar 2023

Ask the Expert: 7 Questions about Colorectal Cancer & Non-invasive Fecal DNA Testing

In this interview, NewsMedical speaks with Dr. Yuying Wang, R&D Director (Oncology), from BGI Genomics, about colorectal cancer and the development and application of COLOTECT® 1.0, a non-invasive fecal DNA test for the detection of colorectal cancer and pre-cancerous lesions.

From BGI Genomics 27 Mar 2023

Possible pathways of C. auris emergence and the hypothetical role of interspecies transmission

Researchers summarized the current understanding of the emergence and ecologic niches of Candida auris.

27 Mar 2023

Advancements in understanding and treating breast cancer

Researchers describe recent advancements in breast cancer research.

26 Mar 2023

High-resolution mass spectrometric rapid identification of Candida auris

A recent study published in the Journal of Fungi used a novel OrbitrapTM high-resolution mass spectrometric technology coupled with liquid chromatography to identify geographically different clades of Candida auris (C. auris) isolates. This proof-of-concept methodology could accurately detect C. auris in the microbiology laboratory.

23 Mar 2023

Candida auris infection without epidemiologic links to a prior outbreak

The Centers for Disease Control and Prevention (CDC) has classified Candida auris (C. auris) as an urgent public threat due to its role in elevating mortality, its ability to persist in hospital environments, and the high possibility of developing pan-drug resistance.

23 Mar 2023

New discovery could help target the causes of aging and cancer development

A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered.

23 Mar 2023

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB.

23 Mar 2023

Study outlines a meta-scale approach to quantifying the human proteome

A major puzzle of biology is that while the human genome contains roughly 20,000 genes, many comparatively primitive organisms - including the universally-studied worm C. elegans - have almost the same number of genes.

23 Mar 2023

INTEGRA Biosciences’ products offer flexibility in the post-pandemic era

From INTEGRA Biosciences 23 Mar 2023

Reinfections with Omicron VOCs occur more frequently and over shorter intervals

In a recent study published in Nature's Communications Biology journal, researchers in the United States of America (USA) employed next-generation sequencing (NGS) data to assess the rise in reinfections with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant.

23 Mar 2023

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

In a recent study published in the journal PLOS Pathogens, researchers in the United States of America (USA) and Canada found molecular evidence that the parasitic hookworms (Ancylostoma caninum) in pet dogs across the USA are becoming increasingly resistant to benzimidazole, a broad-spectrum anthelmintic drug used for infection control.

22 Mar 2023

Higher plasma caffeine concentrations might reduce body fat and type 2 diabetes risk

In a recent study published in the journal BMJ Medicine, researchers in the United Kingdom and Sweden investigated the probable causality of long-term serum caffeine concentrations on type 2 diabetes (T2D), adiposity, and major cardiovascular diseases (CVDs).

22 Mar 2023

Dampened mucosal response against SARS-CoV-2 in pregnant individuals

In a recent study posted to the medRxiv* preprint server, researchers examined associations between coronavirus disease 2019 (COVID-19) outcomes and mucosal antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and viral RNA levels in pregnant individuals.

22 Mar 2023

Genome News and Research

New study suggests broad neutralizing antibody could provide three years of COVID protection

Epigenome reprogramming after SARS-CoV-2 infection

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

New statement suggests next steps to interpret incidentally identified gene variants related to heart disease

New technology can rapidly analyze the metabolic state of lipids in cells

Microbes living in the human body may be acting as a reservoir for antibiotic resistance

Monocytes may be a stable reservoir of HIV in patients taking antiretroviral therapy

Ask the Expert: 7 Questions about Colorectal Cancer & Non-invasive Fecal DNA Testing

Possible pathways of C. auris emergence and the hypothetical role of interspecies transmission

Advancements in understanding and treating breast cancer

High-resolution mass spectrometric rapid identification of Candida auris

Candida auris infection without epidemiologic links to a prior outbreak

New discovery could help target the causes of aging and cancer development

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Study outlines a meta-scale approach to quantifying the human proteome

INTEGRA Biosciences’ products offer flexibility in the post-pandemic era

Reinfections with Omicron VOCs occur more frequently and over shorter intervals

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

Higher plasma caffeine concentrations might reduce body fat and type 2 diabetes risk

Dampened mucosal response against SARS-CoV-2 in pregnant individuals

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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