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KAUST research could open new avenues for cancer drug development

Precise details of how a master regulator of gene expression binds its activating partner could open new avenues for cancer drug development.

10 Oct 2022

Researchers take new approach to studying the development of the human brain

Researchers at ETH Zurich are growing human brain-like tissue from stem cells and are then mapping the cell types that occur in different brain regions and the genes that regulate their development.

7 Oct 2022

Clinical trials of novel COVID-19 vaccine developed in Brazil to begin soon

Testing on humans of a novel COVID-19 vaccine developed in Brazil will begin this year. It performed well in animal trials, as reported in an article published in August in Nature Communications.

6 Oct 2022

Stanford researchers create new technique for controlling protein production

Thanks to new RNA vaccines, we humans have been able to protect ourselves incredibly quickly from new viruses like SARS-CoV-2, the virus that causes COVID-19.

5 Oct 2022

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

In a new study, researchers developed a three-dimensional (3D) in vitro tissue model to assess the effects of SARS-CoV-2 on the vascular endothelial cells.

5 Oct 2022

Key biophysical attributes of a self-amplifying viral RNA vaccine developed for SARS-CoV-2

Researchers used various analytical characterization techniques to determine the biophysical attributes of the Imperial College London self-amplifying viral RNA vaccine (IMP-1) developed for SARS-CoV-2.

5 Oct 2022

Study may have solved a mystery surrounding Crohn’s disease

A new study may have solved a mystery surrounding Crohn's disease, a type of inflammatory bowel disease in which immune defenses meant to attack invading microbes instead mistakenly target the body's own digestive tract.

5 Oct 2022

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

In a new study, researchers determined the 1.8-Å resolution crystal structure of the H1 dual specific phosphatase (DSP) of monkeypox virus (MPXV) that is crucial for viral replication, making it an attractive antiviral target.

5 Oct 2022

PSI researchers optimize a method for tumor diagnosis using radionuclides

Researchers at the Paul Scherrer Institute PSI, in collaboration with ETH Zurich, have optimized a method for tumor diagnosis using radionuclides.

5 Oct 2022

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

In a new study, researchers evaluated the anti-cancer therapeutic efficacy of two structurally-unrelated small molecules, PAV-617 and PAV-951.

4 Oct 2022

Study reveals a promising therapeutic target for spinocerebellar ataxia type 14

Spinocerebellar ataxias are a group of neurodegenerative diseases characterized by the degeneration of Purkinje cells, a major class of neurons in the cerebellum.

3 Oct 2022

Stanford researchers discover a sustainable way to produce cancer-fighting compound in the lab

Stanford University researchers have discovered a rapid and sustainable way to synthetically produce a promising cancer-fighting compound right in the lab.

3 Oct 2022

ASU scientists discover an unusual RNA biogenesis pathway

For the very first time, a study led by Julian Chen and his group in Arizona State University's School of Molecular Sciences and the Biodesign Institute's Center for the Mechanism of Evolution, has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA).

3 Oct 2022

Researchers discover a molecule that promotes tumor cell survival in retinoblastoma

Despite decades of medical advances, children who develop the pediatric eye cancer retinoblastoma often lose their vision or an eye due to a lack of specific, targeted therapies and a poor molecular understanding of the cancer.

3 Oct 2022

Structural analysis of monkeypox virus to guide the development of broad antiviral agents

In a new study, researchers explored the crystalline structure of the monkeypox (MPX) virus (MPXV) and the complex of VP39, a 2′-O-RNA methyltransferase (MTase) and sinefungin, a pan-MTase inhibitor.

30 Sep 2022

Novel technique helps to detangle how phosphorylation regulates cellular events

Each day, millions of biological processes occur in our body at a cellular level. Studying these processes can help us learn more about how cells function, a field that has continued to intrigue researchers.

30 Sep 2022

Research sheds light on how the cell selects suitable protein fragments for robust T-cell response

As task forces of the adaptive immune system, T lymphocytes are responsible for attacking and killing infected or cancerous cells.

30 Sep 2022

Obscure family of viruses already endemic in African monkeys "poised for spillover" to humans

An obscure family of viruses, already endemic in wild African primates and known to cause fatal Ebola-like symptoms in some monkeys, is "poised for spillover" to humans, according to new University of Colorado Boulder research published online Sept. 30 in the journal Cell.

30 Sep 2022

Many diverse nanopore research directions and applications beyond DNA sequencing

In a recent Nature Nanotechnology study, researchers describe diverse applications of nanopore-based technology beyond deoxyribonucleic acid (DNA) sequencing. More specifically, the current research focuses on the advancements of this technology within chemistry, biophysics, and nanoscience.

29 Sep 2022

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Researchers discuss a robust method to identify mutations that improve the expression and stabilize the conformation of the SARS-CoV-2 spike protein.

29 Sep 2022

Molecule News and Research

KAUST research could open new avenues for cancer drug development

Researchers take new approach to studying the development of the human brain

Clinical trials of novel COVID-19 vaccine developed in Brazil to begin soon

Stanford researchers create new technique for controlling protein production

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

Key biophysical attributes of a self-amplifying viral RNA vaccine developed for SARS-CoV-2

Study may have solved a mystery surrounding Crohn’s disease

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

PSI researchers optimize a method for tumor diagnosis using radionuclides

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

Study reveals a promising therapeutic target for spinocerebellar ataxia type 14

Stanford researchers discover a sustainable way to produce cancer-fighting compound in the lab

ASU scientists discover an unusual RNA biogenesis pathway

Researchers discover a molecule that promotes tumor cell survival in retinoblastoma

Structural analysis of monkeypox virus to guide the development of broad antiviral agents

Novel technique helps to detangle how phosphorylation regulates cellular events

Research sheds light on how the cell selects suitable protein fragments for robust T-cell response

Obscure family of viruses already endemic in African monkeys "poised for spillover" to humans

Many diverse nanopore research directions and applications beyond DNA sequencing

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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