Respiratory News and Research

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Oral antivirals Molnupiravir and Nirmatrelvir-Ritonavir lower COVID-19 risks in type 2 diabetes patients

Research investigates the effectiveness of oral antiviral medications, Molnupiravir and Nirmatrelvir-Ritonavir, in treating patients with type 2 diabetes and mild to moderate COVID-19. The study aims to determine the efficacy of these medications in reducing adverse outcomes in this specific population.

24 May 2023

Hypnotic drug class may not have increased the risk of exacerbations and death among COPD patients

Chronic obstructive pulmonary disease patients newly prescribed non-benzodiazepine benzodiazepine receptor agonists (NBZRAs) such as zolpidem (Ambien, Intermezzo and other brands), a class of hypnotic drugs prescribed for insomnia, did not have an increased risk of exacerbations requiring hospitalizations or of death than those prescribed other types of hypnotics, according to research published at the ATS 2023 International Conference.

24 May 2023

Reseachers use CT scans to track the progression of emphysema over time

Researchers at National Jewish Health evaluating computerized tomography (CT) scans of emphysema progression in the COPDGene® study showed that, during a span of 10 years, participants with pre-existing emphysema who continued smoking had the largest decline in adjusted lung density (ALD).

23 May 2023

Research finds fever to be the most common non-respiratory feature of SARS-CoV-2 infection

Fever was found to be the most common non-respiratory feature of infection with SARS-CoV-2, the virus that causes COVID-19, according to research published at the ATS 2023 International Conference.

23 May 2023

AI can help triage patients with respiratory symptoms before primary care clinic visit

Researchers from Iceland trained a machine learning model with artificial intelligence to triage patients with respiratory symptoms before the patients visit a primary care clinic.

23 May 2023

Heart transplants from COVID-19 donors: Mixed outcomes revealed in early analysis

In a recent study published in the Journal of the American College of Cardiology, researchers investigated coronavirus disease 2019 (COVID-19)-infected donor use, donor and recipient characteristics, and early post-heart transplantation (HT) outcomes in the United States (US).

23 May 2023

Vaccination coverage drops in U.S. schools, raising concerns of outbreaks

Research highlights the decline in national coverage of state-required vaccines among kindergarten students during the 2020-2021 and 2021-2022 school years. Despite a low exemption rate, vaccination coverage decreased further in the latter year, indicating ongoing COVID-19 disruptions and emphasizing the need for increased follow-up with under-vaccinated students to protect against vaccine-preventable diseases.

22 May 2023

Targeting mucus plugs could help prevent deaths from COPD, study suggests

A retrospective analysis of patient data from the COPDGene study suggests that targeting mucus plugs could help prevent deaths from chronic obstructive pulmonary disease - the fourth leading cause of death in the United States.

22 May 2023

Climate mitigation efforts could lead to harmful health impacts in certain areas, study finds

Reduce fossil fuel use and air quality will improve, right? It might not be as straightforward as it appears, according to a Penn State-led research team.

22 May 2023

University Hospitals Birmingham partners with Qureight for lung disease research

University Hospitals Birmingham (UHB) has partnered with medical technology company, Qureight, to build more diverse artificial intelligence (AI) models that accurately reflect communities; a world-first lung disease research partnership.

22 May 2023

Genetic insights unveil promising therapeutic targets for critical COVID-19

Critical COVID-19 illness reveals genetic associations with immunomodulatory therapies, as identified in a comprehensive analysis of 24,202 cases. This study uncovers novel genome-wide significant associations, highlighting potential druggable targets for inflammatory signaling, immunometabolism, and viral replication, offering insights into therapeutic implications.

21 May 2023

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Research paper discusses the differences in microbiota between high and low IgA subjects after the second dose of the COVID-19 vaccine. The study found that certain microbial features in breast milk can predict levels of anti-SARS-CoV-2 antibodies in breast milk one week post-second dose.

21 May 2023

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

Research describes the development of a synthetic delivery vector called STxB for mucosal vaccination. It induces mucosal immunity, including resident memory CD8+ T cells and IgA antibodies, against antigens derived from mucosal viruses when administered intranasally in mice.

21 May 2023

Masks and portable air cleaners reduced the spread of COVID-19 in schools, study shows

A new study shows that masking and portable air cleaners reduced the spread of the virus that causes COVID-19 in two Swiss schools.

19 May 2023

Anthropause: the influence of the SARS-CoV-2 outbreak on behavioral patterns of sika deer in Japan

Researchers investigated the impact of the anthropause, or stagnation, in human activity due to a decrease in tourist visits to Nara Park, central Japan, caused by the COVID-19 pandemic, which reduced the population and altered the behavior of Sika deer inhabitants.

19 May 2023

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Researchers derived peptides from the SARS-CoV-2 spike protein to assess COVID-19-associated inflammatory changes using zebrafish models.

19 May 2023

Both vaccine strain and adjuvant selection are critical elements for improving the breadth of protective immunity against enterovirus D68

Researchers demonstrated the production of cross-clade neutralizing antibodies in response to EV-D68.

19 May 2023

Comparing clinical characteristics and outcomes of critically ill COVID-19 patients with a chohort admitted to ICU for influenza pneumonia

A recent study evaluated clinical differences between critically ill COVID-19 and influenza patients.

19 May 2023

Wastewater surveillance reveals hidden scale of mpox rpidemic, challenging official figures

Research highlights the potential of wastewater-based epidemiology as a complementary tool to clinical monitoring for assessing the magnitude of a mpox epidemic. Findings suggest that the presence of mpox DNA in wastewater does not directly correspond to the number of hospitalizations, indicating the underestimation of the epidemic's scale and unidentified cases.

19 May 2023

COVID's latest twist: New XBB variant gains strength through recombination, outsmarting immunity and amplifying fusogenicity

Research discusses the emergence of a highly diversified SARS-CoV-2 Omicron subvariant called XBB, which is spreading rapidly around the world. XBB emerged through the recombination of two cocirculating BA.2 lineages, BJ.1 and BM.1.1.1, during the summer of 2022.

18 May 2023

Respiratory News and Research

Oral antivirals Molnupiravir and Nirmatrelvir-Ritonavir lower COVID-19 risks in type 2 diabetes patients

Hypnotic drug class may not have increased the risk of exacerbations and death among COPD patients

Reseachers use CT scans to track the progression of emphysema over time

Research finds fever to be the most common non-respiratory feature of SARS-CoV-2 infection

AI can help triage patients with respiratory symptoms before primary care clinic visit

Heart transplants from COVID-19 donors: Mixed outcomes revealed in early analysis

Vaccination coverage drops in U.S. schools, raising concerns of outbreaks

Targeting mucus plugs could help prevent deaths from COPD, study suggests

Climate mitigation efforts could lead to harmful health impacts in certain areas, study finds

University Hospitals Birmingham partners with Qureight for lung disease research

Genetic insights unveil promising therapeutic targets for critical COVID-19

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

Masks and portable air cleaners reduced the spread of COVID-19 in schools, study shows

Anthropause: the influence of the SARS-CoV-2 outbreak on behavioral patterns of sika deer in Japan

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Both vaccine strain and adjuvant selection are critical elements for improving the breadth of protective immunity against enterovirus D68

Comparing clinical characteristics and outcomes of critically ill COVID-19 patients with a chohort admitted to ICU for influenza pneumonia

Wastewater surveillance reveals hidden scale of mpox rpidemic, challenging official figures

COVID's latest twist: New XBB variant gains strength through recombination, outsmarting immunity and amplifying fusogenicity

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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