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Additional inhibitor could be key to helping anti-VEGF therapies overcome resistance in glioblastoma

Adding another inhibitor to therapies that cut off a tumor's access to blood vessels could be the key to helping those therapies overcome resistance in glioblastoma, a deadly form of brain cancer.

27 Aug 2018

New personalized cellular therapy approved for use in the European Union

The European Commission has approved a personalized cellular therapy developed at the University of Pennsylvania's Abramson Cancer Center, making it the first chimeric antigen receptor (CAR) T cell therapy permitted for use in the European Union in two distinct indications.

27 Aug 2018

Discovery will allow scientists to target hypoxia in cancer

Researchers have discovered a new GPCR that will allow them to target hypoxia in cancer, offering a new, less harmful treatment for patients.

27 Aug 2018

Some breast cancers can prevent their own spread

Scientists have discovered a mechanism by which people with advanced breast cancer do not experience metastasis and live normal lives.

27 Aug 2018

VTCRI study may disrupt conventional understanding about how electrical activity travels in the heart

Scientists at the Virginia Tech Carilion Research Institute have found evidence that may disrupt conventional understanding about how electrical activity travels in the heart - a discovery that potentially can lead to new insight into medical problems such as heart arrhythmia and sudden cardiac death.

27 Aug 2018

Evotec collaborates with CENTOGENE to develop compounds to treat rare genetic diseases

CENTOGENE today announced that Evotec AG and CENTOGENE AG entered into a global strategic collaboration agreement for joint drug discovery projects, developing compounds to treat rare genetic diseases.

27 Aug 2018

Newly discovered target may prevent progression of liver injury to cancer

Problems like obesity and alcoholism appear to chronically trigger in the liver a receptor known to amplify inflammation in response to invaders like bacteria, scientists report.

27 Aug 2018

New improved method to judge effectiveness of experimental therapies for neurodegeneration

Researchers at UBC's Okanagan campus have developed a new and improved method to judge the effectiveness of experimental therapies for neurodegeneration--the progressive loss of neurons.

27 Aug 2018

Forbius receives $18.75 million grant from CPRIT for Phase 2a development of AVID100

Forbius announced today that it has been awarded a Product Development grant totaling $18.75 million from the Cancer Prevention and Research Institute of Texas.

25 Aug 2018

Changes in TRPV3 genes may have helped mammoths withstand lower temperatures

Columbia University biomedical researchers have captured close-up views of TRPV3, a skin-cell ion channel that plays important roles in sensing temperature, itch, and pain.

25 Aug 2018

New bioprinting method creates tubular structures that mimic vessels, ducts in the body

A team of Brigham and Women's Hospital researchers have developed a way to bioprint tubular structures that better mimic native vessels and ducts in the body.

25 Aug 2018

Study reveals molecular mechanisms underlying expansive arterial remodeling

Expansive arterial remodeling comprises a genetically programmed biological response designed to restore homeostatic levels of arterial wall stress after an increase in vessel flow load occurs.

25 Aug 2018

UTA professor to develop hydrogel that promotes cardiac repair after heart attacks

A UTA bioengineering professor has won a new $460,000 grant from the National Institutes of Health to develop a biodegradable and bioactive hydrogel to repair heart tissue after heart attacks.

25 Aug 2018

Inhibition of miR-24-3p may serve as potential treatment target for mesothelioma

Inhibition of miR-24-3p reduced growth of cancer cells and was found to regulate proteins as a potential treatment target for Mesothelioma.

25 Aug 2018

New pharmacologic approach discovered to stop immune cell death

Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory bowel disease, and arthritis.

24 Aug 2018

INRS professors develop innovative strategy to identify leishmanicidal molecules

Leishmania is a microorganism that enters the human body via a sandfly bite. Instead of fleeing the white blood cells deployed by the immune system to destroy it, the parasite allows itself to be swallowed up.

24 Aug 2018

Research into biology behind sperm development could offer hope for solving male infertility

Nearly one in eight couples in the U.S. face infertility, and about half of those cases can be attributed to semen abnormalities in the male partner.

24 Aug 2018

Researchers identify series of molecules involved in regeneration of damaged nerves

Researchers at Nagoya University have identified the series of molecules involved in the regeneration of damaged nerves in roundworm, showing that it largely overlaps with the signals used by the intrinsic removal system to take up and process dying cells.

24 Aug 2018

MSU researchers move one step closer to solving arthritic disease in teenagers

A new Michigan State University study has found that a malfunctioning gene associated with a common arthritic disease that often starts in teenagers is now directly linked to the loss of vital immune cells that may prevent it.

24 Aug 2018

Scientists identify molecular pit crew responsible for refueling in signaling cells

During IndyCar races, pit stop crews will often refuel a car, replace wheels and complete minor repairs on a race car within 10 seconds. In this short time, a dozen or so people work rapidly and in a highly coordinated manner to complete a number of tasks with extraordinary efficiency.

24 Aug 2018

B Cell News and Research

Additional inhibitor could be key to helping anti-VEGF therapies overcome resistance in glioblastoma

New personalized cellular therapy approved for use in the European Union

Discovery will allow scientists to target hypoxia in cancer

Some breast cancers can prevent their own spread

VTCRI study may disrupt conventional understanding about how electrical activity travels in the heart

Evotec collaborates with CENTOGENE to develop compounds to treat rare genetic diseases

Newly discovered target may prevent progression of liver injury to cancer

New improved method to judge effectiveness of experimental therapies for neurodegeneration

Forbius receives $18.75 million grant from CPRIT for Phase 2a development of AVID100

Changes in TRPV3 genes may have helped mammoths withstand lower temperatures

New bioprinting method creates tubular structures that mimic vessels, ducts in the body

Study reveals molecular mechanisms underlying expansive arterial remodeling

UTA professor to develop hydrogel that promotes cardiac repair after heart attacks

Inhibition of miR-24-3p may serve as potential treatment target for mesothelioma

New pharmacologic approach discovered to stop immune cell death

INRS professors develop innovative strategy to identify leishmanicidal molecules

Research into biology behind sperm development could offer hope for solving male infertility

Researchers identify series of molecules involved in regeneration of damaged nerves

MSU researchers move one step closer to solving arthritic disease in teenagers

Scientists identify molecular pit crew responsible for refueling in signaling cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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