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Finding ways to improve cell replacement therapy for Parkinson's disease

Parkinson's disease is a neurodegenerative disease that affects dopamine signaling neurons in patients' brains. Cell-replacement therapy shows some promise as a treatment for Parkinson's. A recent paper in the journal Molecular & Cellular Proteomics reports a technical advance in selecting cells to use in this therapy.

24 Aug 2018

Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

St. Jude Children's Research Hospital investigators have completed the most comprehensive analysis yet of a common pediatric solid tumor, identifying weaknesses to target and a promising precision medicine that is now in clinical trials.

23 Aug 2018

Study provides new clues to connection between aging and neurodegeneration

For decades researchers have worked to shed light on the causes of neurodegenerative disorders, a group of devastating conditions, including Alzheimer's and Parkinson's, that involve the progressive loss of neurons and nervous system function. In recent years, numerous factors, from genetic mutations to viral infections, have been found to contribute to the development of these diseases.

23 Aug 2018

'Plastic antibodies' effectively target and eliminate tumor cells

A joint research team from Russia and the U.K. has demonstrated the possibility of developing a new type of anti-neoplastic drugs based on nanoMIPs, or "plastic antibodies." NanoMIPs are synthetic polymers that can function as antibodies, selectively binding to target proteins on the surface of cancer cells.

23 Aug 2018

GW researchers to develop model for studying role of COMPASS protein in pancreatic cancer

Pancreatic cancer is the fourth most common cause of cancer related deaths in the United States with a five-year survival rate of less than 10 percent. Although it is defined by a small number of genetic alterations, efforts to pharmacologically target specific pathways have been unsuccessful.

23 Aug 2018

Scientists identify novel biomarkers that indicate risk of polyneuropathy

Polyneuropathy is one of the most common complications in people with diabetes. However, it can also occur with certain risk factors or diseases before the onset of diabetes.

23 Aug 2018

Neonatal immune system starts to change dramatically in response to bacteria, viruses

As soon as a baby is born, its immune system starts to change dramatically in response to the bacteria, viruses and so forth in its new environment, a phenomenon that is common to all babies, researchers from Karolinska Institutet in Sweden write in a paper published in Cell.

23 Aug 2018

Scientists demonstrate rapid immune system development in newborn babies

Using new analytical techniques, researchers have shown for the first time the dramatic development of the human immune system after birth.

23 Aug 2018

Sleep loss can confer increased risk of adverse weight gain, shows study

In a new study, researchers at Uppsala University now demonstrate that one night of sleep loss has a tissue-specific impact on the regulation of gene expression and metabolism in humans.

23 Aug 2018

Bluebird bio collaborates with Gritstone Oncology to develop novel cancer cell therapies

Bluebird bio, Inc. and Gritstone Oncology, Inc. today announced a collaboration to research, develop and commercialize products for the treatment of cancer using cell therapy.

23 Aug 2018

Location of proteins on bacterial surface can impact pathogenicity of pneumococcal strains

Successful pathogenic strains of pneumococci have two proteins that, owing to their location on the surface of the bacteria, enhance their survival and ability to cause disease, a study from Karolinska Institutet in Sweden published in Nature Communications, reports.

23 Aug 2018

New imaging technique allows mapping electrical activity in single neurons

Our brain cells control every aspect of our lives - from the movements we make to the memories we form. But capturing the activity of neurons in the form of electric impulses isn't easy.

23 Aug 2018

Qlu Health launches in the UK

A new genetic health testing company that focuses on preventing life altering medical conditions before they are apparent rather than reacting to them has launched in the UK. Qlu Health offers cancer, cardiac, nutrition and gut testing.

23 Aug 2018

AVITA Medical: Clinical trial results demonstrate safety, efficacy of RECELL Device in treating burn patients

AVITA Medical today announced that results from two U.S. pivotal clinical trials demonstrating the effectiveness and clinical benefits of the RECELL Autologous Cell Harvesting Device were presented in the plenary session at the U.S. Defense Department Military Health System Research Symposium (MHSRS) in Kissimmee, Florida.

23 Aug 2018

Harvard scientists end 40-year-quest for elusive identity of 'hearing' protein

Scientists at Harvard Medical School say they have ended a 40-year-quest for the elusive identity of the sensor protein responsible for hearing and balance.

23 Aug 2018

Eisai: EC approves marketing of LENVIMA as first-line treatment for hepatocellular carcinoma

Eisai Co., Ltd. and Merck & Co., Inc., Kenilworth N.J., U.S.A., known as MSD outside of the United States and Canada, announced today that the European Commission has granted a marketing authorization for the oral receptor tyrosine kinase inhibitor LENVIMA (lenvatinib mesylate) as a single agent for the first-line treatment of adult patients with advanced or unresectable hepatocellular carcinoma who have received no prior systemic therapy.

23 Aug 2018

Scientists work towards solving mystery of incurable blood diseases

Scientists may be on the road to solving the mystery of a group of mostly incurable blood diseases called myelodysplastic syndromes, which cause people to have immature, malfunctioning bone marrow cells that fuel a diverse set of health problems and can lead to leukemia.

23 Aug 2018

Research identifies cell signaling pathways related to endocannabinoid system in worms

Like mammals, parasitic worms have an endocannabinoid system that may help the worm and the hosts it infects survive by reducing pain and inflammation in the host, according to a "wild" new discovery by an interdisciplinary research team at the University of California, Riverside.

23 Aug 2018

Researchers describe how RNA polymerase detects UV light damage in DNA

Damage to DNA is a constant threat to cellular life, and so it is constantly monitored and detected by a family of enzymes called RNA polymerases, resulting in subsequent repair to maintain genome integrity.

23 Aug 2018

I-antigen plays major role in glycan-mediated processes, shows study

Two new studies have unveiled how a peculiar molecule impacts how antibody-producing cells develop and function as well as how normal melanocytes progress to melanoma malignancy.

23 Aug 2018

B Cell News and Research

Finding ways to improve cell replacement therapy for Parkinson's disease

Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

Study provides new clues to connection between aging and neurodegeneration

'Plastic antibodies' effectively target and eliminate tumor cells

GW researchers to develop model for studying role of COMPASS protein in pancreatic cancer

Scientists identify novel biomarkers that indicate risk of polyneuropathy

Neonatal immune system starts to change dramatically in response to bacteria, viruses

Scientists demonstrate rapid immune system development in newborn babies

Sleep loss can confer increased risk of adverse weight gain, shows study

Bluebird bio collaborates with Gritstone Oncology to develop novel cancer cell therapies

Location of proteins on bacterial surface can impact pathogenicity of pneumococcal strains

New imaging technique allows mapping electrical activity in single neurons

Qlu Health launches in the UK

AVITA Medical: Clinical trial results demonstrate safety, efficacy of RECELL Device in treating burn patients

Harvard scientists end 40-year-quest for elusive identity of 'hearing' protein

Eisai: EC approves marketing of LENVIMA as first-line treatment for hepatocellular carcinoma

Scientists work towards solving mystery of incurable blood diseases

Research identifies cell signaling pathways related to endocannabinoid system in worms

Researchers describe how RNA polymerase detects UV light damage in DNA

I-antigen plays major role in glycan-mediated processes, shows study

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