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Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for toxigenic lineage M1UK

Study explores the emerging invasive group A Streptococcus M1uk lineage,

7 Apr 2023

UW researchers engineer stem cells that do not generate dangerous arrhythmias

Researchers at the University of Washington School of Medicine in Seattle have engineered stem cells that do not generate dangerous arrhythmias, a complication that has to date thwarted efforts to develop stem-cell therapies for injured hearts.

7 Apr 2023

Study sheds new light on the spread of COVID-19 in households

A new Imperial College London-led study provides the first empirical evidence for transmission of SARS-CoV-2 via people's hands and frequently touched household surfaces.

6 Apr 2023

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes.

6 Apr 2023

Revolution in MDR-TB treatment: Shorter all-oral regimens

Researchers reported on the evolution of multidrug-resistant tuberculosis (MDR-TB) therapy.

6 Apr 2023

Complex assembly process involved in DNA virus replication revealed

In a twist on the question, "Which came first, the chicken or the egg?", scientists have long faced a similar question about how human adenovirus replicates: "Which comes first, assembly of the viral particle, or packaging of the viral genome?"

5 Apr 2023

UCI biologists discover how to ward off harmful effects caused by a high-fat diet

Eating lots of fats increases the risk of metabolic disorders, but the mechanisms behind the problem have not been well understood.

5 Apr 2023

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

The scientific foundation needed to work on curing a class of cancer-causing mutations is here, in the form of a tool from St. Jude Children's Research Hospital.

5 Apr 2023

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Mosaic Therapeutics, an oncology therapeutics company dedicated to resolving cancer’s complexity to power new treatments for patients, today announced the close of its $28 million series A funding round.

From Mosaic Therapeutics 4 Apr 2023

CRISPR screens reveal genetic determinants of PARP inhibition in prostate cancer

Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive.

4 Apr 2023

Healthy sleep pattern may help offset asthma risk regardless of genetic susceptibility

Poor quality sleep may bolster a person's genetic susceptibility to asthma, potentially doubling their risk of being diagnosed with the condition, suggests a large UK Biobank study, published in the open access journal BMJ Open Respiratory Research.

4 Apr 2023

New software tool uses genetic data to improve cancer modeling technology

Lifestyle behaviors such as eating well and exercising can be significant factors in one's overall health. But the risk of developing cancer is predominantly at the whim of an individual's genetics.

4 Apr 2023

Unique brain proteins may be critical regulators of body weight

Genetic factors could contribute to up to 50-75% of the variance in body mass index, or BMI, in the population.

4 Apr 2023

Elucidating the function of BRCA2 gene offers insight into cancer development

A new study shows exactly how the gene BRCA2, linked to susceptibility to breast and ovarian cancer, functions to repair damaged DNA.

3 Apr 2023

Study elucidates the genetics of preterm birth and pregnancy length

New knowledge of the genetic factors behind premature delivery and gestational duration has now emerged.

3 Apr 2023

Yale-led team creates new resource that is an important step toward personalized care

Each person has about 4 million sequence differences in their genome relative to the reference human genome.

3 Apr 2023

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Researchers reviewed the existing knowledge on the mechanisms through which DNA tumor viruses evade the antiviral immunity mediated through mis-incorporated uracil (U).

3 Apr 2023

The association between regular glucosamine use and risk of dementia

Researchers assessed the association between daily glucosamine consumption and the risk of new-onset dementia.

3 Apr 2023

Transposable elements in various cancers could be used to harness novel immunotherapies

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors that don't typically respond to immune-based treatments. Shown is a 3D rendering of cancer cells.

31 Mar 2023

Study shows a genetic association of diarrhea in children

Susceptibility to diarrhea, a major cause of infant deaths in low- and middle-income countries, has genetic links which could hold the key to new treatments, research suggests.

31 Mar 2023

Genome News and Research

Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for toxigenic lineage M1UK

UW researchers engineer stem cells that do not generate dangerous arrhythmias

Study sheds new light on the spread of COVID-19 in households

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Revolution in MDR-TB treatment: Shorter all-oral regimens

Complex assembly process involved in DNA virus replication revealed

UCI biologists discover how to ward off harmful effects caused by a high-fat diet

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

CRISPR screens reveal genetic determinants of PARP inhibition in prostate cancer

Healthy sleep pattern may help offset asthma risk regardless of genetic susceptibility

New software tool uses genetic data to improve cancer modeling technology

Unique brain proteins may be critical regulators of body weight

Elucidating the function of BRCA2 gene offers insight into cancer development

Study elucidates the genetics of preterm birth and pregnancy length

Yale-led team creates new resource that is an important step toward personalized care

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

The association between regular glucosamine use and risk of dementia

Transposable elements in various cancers could be used to harness novel immunotherapies

Study shows a genetic association of diarrhea in children

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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