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Tissue-resident memory cells are key to immunity to Salmonella in mice

Salmonella infections cause about a million deaths a year worldwide, and there is an urgent need for better vaccines for both typhoid fever and non-typhoidal Salmonella disease.

18 Apr 2023

Are non-nutritive sweeteners harming your gut microbiota?

This paper discusses the impact of non-nutritive sweeteners (NNS) on the gut microbiota, which is essential in maintaining normal gut physiology and health.

18 Apr 2023

Study shows how a biological clock molecule contributes to lung scarring

Abnormal sleep patterns, like those of night-shift workers, disrupt the body's natural biological clock and have been linked to lung health issues.

17 Apr 2023

New $2.3 million NCI grant awarded to Georgia Cancer Center to improve survival of patients with AML

Acute myeloid leukemia (AML) is a cancer that affects blood cells in the bone marrow - the spongy tissue inside certain bones, where new blood cells are made.

17 Apr 2023

Pre- and post-surgical immunotherapy-based treatment significantly improved lung cancer outcomes

A regimen of pre-surgical immunotherapy and chemotherapy followed by post-surgical immunotherapy significantly improved event-free survival (EFS) and pathologic complete response (pCR) rates compared to chemotherapy alone for patients with operable non-small cell lung cancer (NSCLC), according to Phase III trial results presented today by researchers from The University of Texas MD Anderson Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2023.

17 Apr 2023

A review of the risk factors associated with cancer evolution

Researchers reviewed existing data on tumor-promotive risk factors and their underlying mechanisms.

17 Apr 2023

First-ever largest atlas of post-zygotic genome mutations in healthy human tissue created

Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled - a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease.

13 Apr 2023

Researchers develop new approach for studying HBV in the lab

Hepatitis C and hepatitis B viruses both attack the liver, eventually causing deadly cirrhosis or cancer. But while antivirals can cure 95 percent of HCV infections, its cousin HBV has long eluded effective therapeutics.

13 Apr 2023

Curtin researchers identify the genetic signature of pre-malignant liver cells

Researchers at Curtin University have identified the genetic signature of pre-malignant liver cells, offering potentially significant implications for the almost 3,000 Australians diagnosed with the deadly cancer each year.

13 Apr 2023

Machine learning methods may be effective in screening patients for sleep disorder risk

A machine learning model can effectively predict a patient's risk for a sleep disorder using demographic and lifestyle data, physical exam results and laboratory values, according to a new study published this week in the open-access journal PLOS ONE by Samuel Y. Huang of Virginia Commonwealth University School of Medicine, and Alexander A. Huang of Northwestern Feinberg University School of Medicine, US.

12 Apr 2023

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost impossible because of the tumors' location.

12 Apr 2023

Unexpected discovery could inspire new strategies for preventing liver disease and cancer

Liver cancer is the third leading cause of cancer death and the sixth most common cancer type worldwide.

12 Apr 2023

Mutant Salmonella strains cause more severe infections than wild-type bacteria in chickens

In Brazil, a group of researchers supported by FAPESP created mutant forms of Salmonella to understand the mechanisms that favor colonization of the intestinal tract of chickens by these pathogenic bacteria and find better ways to combat the infection they cause.

11 Apr 2023

UC-led research team receives NIH grant to study the role of an enzyme in lysosome function

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes.

11 Apr 2023

Genetically-engineered probiotic could be a new way to reduce alcohol-induced health problems

Excessive alcohol consumption leads to painful hangovers and accompanying headaches, fatigue, and nausea.

11 Apr 2023

SARS-CoV-2 may exploit multiple receptors and pathways across various tissues, age groups

A study led by Mount Sinai researchers Dr. Bin Zhang, the Willard T.C. Johnson Research Professor of Neurogenetics, and Dr. Christian Forst, an Associate Professor in the Department of Genetics and Genomic Sciences, have identified potential novel receptors for SARS-CoV-2 and unveiled their tissue-specific and age-dependent expression.

11 Apr 2023

Researchers detect cancer-causing chemicals in toys and headphones

Cancer-causing chlorinated paraffins are still used in a wide range of everyday products sold in North America despite their known health harm and being banned in Canada for a decade, according to a new peer-reviewed study in Environmental Science: Processes & Impacts.

11 Apr 2023

Prenatal and early childhood nutritional exposures: a review of the developmental contributions to obesity

Researchers reviewed the latest studies on nutritional exposures during prenatal and early childhood stages.

11 Apr 2023

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers report on the benefits of consuming dietary phenols and their relationship with the intestinal microbiome.

10 Apr 2023

Study examines whether alcohol-associated burn injuries impair cognitive function

The relationship between alcohol use and burn injuries is a negative one in multiple ways. Not only are about 50% of adults who sustain burn injuries intoxicated at the time of injury, suggesting that alcohol use may have contributed to the incident, but alcohol use among burn-injured patients is associated with more severe complications, delayed recovery, and increased morbidity and mortality.

10 Apr 2023

Liver News and Research

Tissue-resident memory cells are key to immunity to Salmonella in mice

Are non-nutritive sweeteners harming your gut microbiota?

Study shows how a biological clock molecule contributes to lung scarring

New $2.3 million NCI grant awarded to Georgia Cancer Center to improve survival of patients with AML

Pre- and post-surgical immunotherapy-based treatment significantly improved lung cancer outcomes

A review of the risk factors associated with cancer evolution

First-ever largest atlas of post-zygotic genome mutations in healthy human tissue created

Researchers develop new approach for studying HBV in the lab

Curtin researchers identify the genetic signature of pre-malignant liver cells

Machine learning methods may be effective in screening patients for sleep disorder risk

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Unexpected discovery could inspire new strategies for preventing liver disease and cancer

Mutant Salmonella strains cause more severe infections than wild-type bacteria in chickens

UC-led research team receives NIH grant to study the role of an enzyme in lysosome function

Genetically-engineered probiotic could be a new way to reduce alcohol-induced health problems

SARS-CoV-2 may exploit multiple receptors and pathways across various tissues, age groups

Researchers detect cancer-causing chemicals in toys and headphones

Prenatal and early childhood nutritional exposures: a review of the developmental contributions to obesity

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Study examines whether alcohol-associated burn injuries impair cognitive function

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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