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Optimizing the operation of MRI scanners to visualize finer details of the brain

Experts in magnetic resonance imaging (MRI) at the DZNE are optimizing the operation of MRI scanners as part of an international research effort to enable visualization of finer details of the human brain.

12 Jul 2021

New research examines the elimination of the B.1.362 + L452R variant in Israel

Is it possible to completely get rid of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants? New research led by Neta S. Zuckerman of Sheba Medical Center in Israel suggests it’s possible. Their report details the upsurge of a B.1.362 variant harboring the L452R mutation that eventually disappeared due to vaccination efforts and the presence of more robust variants.

12 Jul 2021

The progressive increase in transmissibility and virulence of emerging SARS-CoV-2 variants could lead to a significantly more deadly pandemic

Researchers from Toronto University, Canada, recently showed that these emerging VOCs were linked to increased virulence, as determined by hospitalization risk, ICU admission, and mortality. This study is currently available on the medRxiv* preprint server.

12 Jul 2021

Malfunction in the cell’s powerhouse causes sporadic Parkinson disease

The major cause of Parkinson’s Disease is a dysregulation of immune genes central for fighting against viruses, a new study reveals.

9 Jul 2021

New York City SARS-CoV-2 breakthrough cases predominantly Alpha and Iota variants

While Delta (B.1.617.2) has overtaken Alpha (B.1.1.7) as the dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant in the United States, Alpha remained a force to be reckoned with in New York City earlier this year. New research published on the preprint medRxiv* server details breakthrough infections in vaccinated and unvaccinated individuals living in New York City.

9 Jul 2021

Researchers model probability of extinction of SARS-CoV-2 variant in an outbreak

However, it cannot be confirmed for certain that the strain has been eliminated, raising the question of how long a strain must go undetected before being considered, in all probability, extinct.

9 Jul 2021

Why is the SARS-CoV-2 Delta variant so concerning?

As cases surge in the United States, health experts have raised the alarm that vaccinated individuals may be spreading the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant. Over half of new infections in the U.S. are now caused by this highly transmissible variant.

9 Jul 2021

Breakthrough SARS-CoV-2 infection among fully vaccinated likely to be less transmissible

Researchers in the United States have conducted a study suggesting that individuals fully vaccinated against coronavirus disease 2019 (COVID-19) who develop breakthrough infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are less likely to transmit the virus to others than unvaccinated infected individuals.

8 Jul 2021

Scientists discover drug candidates for treating liver fibrosis among pesticides

Skoltech biologists and their colleagues from Koltzov Institute of Developmental Biology, Russia, and the Chemistry Department of Taras Shevchenko University in Ukraine have discovered fairly unlikely drug candidates for treating liver fibrosis and other pathologies -- among pest control chemicals.

8 Jul 2021

Study uncovers mutations in Polycomb group gene as underlying cause of novel neurological disorder

A multi-institutional study has discovered spontaneous mutations in RNF2 (RING2) gene as the underlying cause of a novel neurological disorder.

8 Jul 2021

Do lockdowns exert selection pressure on overdispersion of SARS-CoV-2 variants?

New research recently released on the medRxiv* preprint server describes a mathematical model that has been developed to evaluate competitions between variants that differ in their level of overdispersion (k) and their mean infectiousness.

8 Jul 2021

Scientists study how our immune system responds to COVID-19 variants

Australian scientists researching how our immune system responds to COVID-19 have revealed that those infected by early variants in 2020 produced sustained antibodies, however, these antibodies are not as effective against contemporary variants of the virus.

8 Jul 2021

How SARS-CoV-2 has evolved over the course of the pandemic

In an effort to understand the ongoing evolution of the SARS-CoV-2 genome, researchers constructed a phylogenetic tree of all available SARS-CoV-2 genomes.

7 Jul 2021

B.1.1.7 variant of SARS-CoV-2 is more transmissible than B.1.526

A new paper available on the medRxiv* preprint server presents evidence that the B.1.1.7 VOC is more transmissible than the B.1.526 strain.

7 Jul 2021

B.1.427/B.1.429 variant of SARS-CoV-2 evades neutralization via disulfide bond rearrangement

A new paper discusses an intriguing new mechanism of immune evasion traceable to specific mutations in the B.1.427/B.1.429 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

7 Jul 2021

Common anti-coagulant drug could treat emerging variants of SARS-CoV-2

QUT PhD researcher Zachariah Schuurs said the research team had identified a new binding site on the SARS-CoV-2 spike protein.

7 Jul 2021

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

In a new study on mice, Johns Hopkins Medicine researchers report that using MRI scans to measure blood volume in the brain can serve as a noninvasive way to potentially track the progress of gene editing therapies for early-stage Huntington's disease, a neurodegenerative disorder that attacks brain cells.

7 Jul 2021

New study reports low SARS-CoV-2 breakthrough infections in vaccinated healthcare workers

Researchers examined cases of SARS-CoV-2 infection in fully and partially vaccinated healthcare workers, finding that vaccination provided strong immunity to the virus even though VOCs are on the rise in the non-vaccinated community at large.

7 Jul 2021

Mutations in the Epsilon variant contribute to SARS-CoV-2 immune evasion

Three mutations in the Epsilon coronavirus spike protein dampen the neutralizing potency of antibodies induced by current vaccines or past COVID infections.

6 Jul 2021

Study explores how human ACE2 variants can modify SARS-CoV-2 binding

A recent tour-de-force study by researchers from the United Kingdom reveals variants of the human angiotensin-converting enzyme 2 (ACE2) that can improve or decrease binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – including two variants with distinct population distributions showing an enhanced affinity for viral spike glycoprotein.

5 Jul 2021

Mutation News and Research

Optimizing the operation of MRI scanners to visualize finer details of the brain

New research examines the elimination of the B.1.362 + L452R variant in Israel

The progressive increase in transmissibility and virulence of emerging SARS-CoV-2 variants could lead to a significantly more deadly pandemic

Malfunction in the cell’s powerhouse causes sporadic Parkinson disease

New York City SARS-CoV-2 breakthrough cases predominantly Alpha and Iota variants

Researchers model probability of extinction of SARS-CoV-2 variant in an outbreak

Why is the SARS-CoV-2 Delta variant so concerning?

Breakthrough SARS-CoV-2 infection among fully vaccinated likely to be less transmissible

Scientists discover drug candidates for treating liver fibrosis among pesticides

Study uncovers mutations in Polycomb group gene as underlying cause of novel neurological disorder

Do lockdowns exert selection pressure on overdispersion of SARS-CoV-2 variants?

Scientists study how our immune system responds to COVID-19 variants

How SARS-CoV-2 has evolved over the course of the pandemic

B.1.1.7 variant of SARS-CoV-2 is more transmissible than B.1.526

B.1.427/B.1.429 variant of SARS-CoV-2 evades neutralization via disulfide bond rearrangement

Common anti-coagulant drug could treat emerging variants of SARS-CoV-2

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

New study reports low SARS-CoV-2 breakthrough infections in vaccinated healthcare workers

Mutations in the Epsilon variant contribute to SARS-CoV-2 immune evasion

Study explores how human ACE2 variants can modify SARS-CoV-2 binding

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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