Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Proton pump inhibitors linked to increased death risk

Proton pump inhibitors (PPIs) are one of the commonest agents prescribed for heart burn or acid reflux. These agents are available for purchase over-the-counter making them one of the most commonly used drugs that make around $10 billion in annual sales. PPIs work by reducing the production of the gastric acids in the stomach. There are several known risks associated with PPI use including complete stoppage of gastric acid production, risk of pneumonia, kidney disorders, bone fractures such as hip fractures etc.

5 Jul 2017

Schistosomiasis: the biggest killer you’ve never heard of?

Schistosomiasis is a parasitic disease, sometimes called bilharzia or snail fever. The disease impacts a huge number of people around the world, over 230 million people are infected with one of the schistosome species, the parasitic worms that causes the disease.

4 Jul 2017

Commonly prescribed gastric acid drug may increase death risk, study shows

Long-term use of a popular class of drug called proton pump inhibitors (PPIS) has been linked to an increased risk of death in a study published in BMJ Open. The findings add to a growing body of evidence linking the use of PPIs to a range of health problems including kidney damage, bone fracture and dementia.

4 Jul 2017

Longtime use of heartburn drugs linked to increased risk of death

Popular heartburn drugs called proton pump inhibitors (PPIs) have been linked to a variety of health problems, including serious kidney damage, bone fractures and dementia.

4 Jul 2017

Google’s DeepMind project and Royal Free Trust breach patient privacy laws

In a breach of patient trust, a British hospital shared the personal information of around 1.6 million patients with Google's DeepMind. This was reported by a British data protection watchdog - Information Commissioner's Office (ICO) yesterday, creating a stir. The deal between the Royal Free NHS Trust and Google’s DeepMind first became known to the public in February 2016.

3 Jul 2017

Novel technique to monitor nerve function could transform the way doctors perform surgeries

In a first-of-its-kind study, Mount Sinai researchers have discovered a novel technique to monitor laryngeal and vagus nerve function while patients are under anesthesia during otolaryngology and neurosurgery procedures.

3 Jul 2017

Researchers develop new biocompatible materials for soft-tissue adhesion

Researchers at Okayama University describe in Acta Biomaterialia a new type of biocompatible adhesive material. The adhesive, made from nanoparticles of hydroxyapatite, glues both synthetic hydrogels and mouse soft tissue, providing a promising alternative to organic materials currently in use for clinical applications.

30 Jun 2017

Catheter use during hemodialysis linked to increased rates of bloodstream infections

Using catheters to access the blood during hemodialysis continues to be linked with increased rates of bloodstream infections, according to a recent analysis of data from US dialysis facilities. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

30 Jun 2017

UD researchers combat chronic kidney disease with exercise

A University of Delaware research team in the College of Health Sciences is combating chronic kidney disease (CKD) with exercise.

28 Jun 2017

Study could help surgeons choose best approaches for hearing preservation in cochlear implant patients

Cochlear implants that have electrodes designed without wire perform better than those with wires for long-term hearing preservation, a Mount Sinai researcher has reported in a first-of-its-kind study.

27 Jun 2017

Elevated levels of suPAR protein combine with genetic mutation to trigger CKD in black people

Between 15 and 20 percent of black people carry a genetic mutation that puts them at risk for certain chronic kidney disease, but only about half of them develop the illness – a variance that long has puzzled researchers.

27 Jun 2017

Innate immune cells of myeloid lineage play central role in AD pathogenesis than previously thought

Many genes linked to late-onset Alzheimer's disease (AD) are expressed in myeloid cells and regulated by a single protein, according to research conducted at the Icahn School of Medicine at Mount Sinai and published June 19 in the journal Nature Neuroscience.

27 Jun 2017

Drug cocktail may be effective in preventing progressive organ dysfunction, deaths from sepsis

Sepsis presents a major challenge for health care providers, especially in low-income countries where the mortality rate can exceed 60 percent.

27 Jun 2017

Scientists find lack of experimental evidence detailing biologic roles of leptin in metabolism

Discovered more than two decades ago, the hormone leptin has been widely hailed as the key regulator of leanness. Yet, the pivotal experiments that probe the function of this protein and unravel the precise mechanism of its action as a guardian against obesity are largely missing.

24 Jun 2017

Experimental drug benefits some patients with advanced kidney cancer

Some patients with a form of advanced kidney cancer that carries a poor prognosis benefited from an experimental drug targeted to an abnormal genetic pathway causing cancerous growth, according to research led by a Dana-Farber Cancer Institute scientist.

24 Jun 2017

Scientists discover link between sugar metabolism and peroxisomal biogenesis disorders

Meeting a young patient with Zellweger syndrome, a rare, life-threatening genetic disease, started a scientific investigation that culminated with an unexpected discovery.

23 Jun 2017

Intensive blood pressure lowering reduces CKD patients' risks of heart disease and death

Results from a recent clinical trial indicate that intensive blood pressure lowering reduces chronic kidney disease patients' risks of dying prematurely or developing cardiovascular disease. The findings appear in an upcoming issue of the Journal of the American Society of Nephrology.

23 Jun 2017

Human colon organoids fill gap in effectively modeling common GI diseases

Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according to research published June 22 in Cell Stem Cell.

22 Jun 2017

Study suggests many people in the U.S. are taking too much vitamin D

An increasing number of adults in the U.S. are taking too much vitamin D, say researchers, with 3% supplementing at doses that have previously been associated with an increased risk of serious side effects such as kidney stones, certain cancers and even death.

21 Jun 2017

Study suggests sons of older fathers have characteristics of ‘geeks’

Sons of older fathers are more intelligent, more focused on their interests, and less concerned about fitting in, all characteristics typically seen in "geeks," according to research conducted at The Seaver Autism Center for Research and Treatment at the Icahn School of Medicine at Mount Sinai and published on June 20 in the journal Translational Psychiatry.

21 Jun 2017

Nephrology News and Research

Further Reading

Proton pump inhibitors linked to increased death risk

Schistosomiasis: the biggest killer you’ve never heard of?

Commonly prescribed gastric acid drug may increase death risk, study shows

Longtime use of heartburn drugs linked to increased risk of death

Google’s DeepMind project and Royal Free Trust breach patient privacy laws

Novel technique to monitor nerve function could transform the way doctors perform surgeries

Researchers develop new biocompatible materials for soft-tissue adhesion

Catheter use during hemodialysis linked to increased rates of bloodstream infections

UD researchers combat chronic kidney disease with exercise

Study could help surgeons choose best approaches for hearing preservation in cochlear implant patients

Elevated levels of suPAR protein combine with genetic mutation to trigger CKD in black people

Innate immune cells of myeloid lineage play central role in AD pathogenesis than previously thought

Drug cocktail may be effective in preventing progressive organ dysfunction, deaths from sepsis

Scientists find lack of experimental evidence detailing biologic roles of leptin in metabolism

Experimental drug benefits some patients with advanced kidney cancer

Scientists discover link between sugar metabolism and peroxisomal biogenesis disorders

Intensive blood pressure lowering reduces CKD patients' risks of heart disease and death

Human colon organoids fill gap in effectively modeling common GI diseases

Study suggests many people in the U.S. are taking too much vitamin D

Study suggests sons of older fathers have characteristics of ‘geeks’

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