Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Cerebrospinal fluid autoantibodies target the brain in some COVID-19 patients

A study conducted by German researchers has shown that the neurological symptoms observed in some patients with coronavirus disease 2019 (COVID-19) may be caused by autoantibodies targeting the brain.

7 Jul 2020

Newly discovered endometrial cancer biomarker enables early detection and treatment

A newly discovered endometrial (uterine) cancer biomarker and diagnostic method will enable detection of the tumor type that is likely to spread and recur so that clinicians can initiate treatment early and stop the cancer from attacking other parts of the body.

3 Jul 2020

Repeated sampling of FIB-4 score can increase the prediction of future liver cirrhosis

Repeated measurements of the biomarker FIB-4 in the blood every few years can predict the risk of developing severe liver disease, according to a new study from Karolinska Institutet in Sweden published in the Journal of Hepatology.

1 Jul 2020

Research shows IQGAP1 as a common target in variants of triple negative breast cancer

The cover for issue 26 of Oncotarget features Figure 6, "Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells," by Osman, et al. and reported that IQGAP1 is a signaling scaffold implicated in TNBC, but its mechanism is unknown.

30 Jun 2020

Potential new biomarker could improve COVID-19 diagnosis

Researchers at Montpellier University Hospital have discovered that an interferon-inducible receptor expressed on monocytes could be a useful biomarker for the rapid triaging of patients suspected to have severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

30 Jun 2020

Scientists discover mechanism involving key protein that predicts cancer progression and relapse

Cancer cases have been rising over the years and according to the statistics, the number of people living with cancer will continue to increase.

30 Jun 2020

New method for analyzing intact tumor samples to be used for studying COVID-19

Researchers at Karolinska Institutet in Sweden have developed a new method for analyzing intact tumor samples in 3D on a molecular level.

29 Jun 2020

Smart MRI scan used for heart disease can help assess aggressive cancers in children

A type of smart MRI scan used in people with heart disease could help assess whether children's cancers are especially aggressive and spot early signs that targeted treatments are working, a new study suggests.

29 Jun 2020

New rapid genomic testing can improve therapy selection for colorectal cancer patients

Genomic mutation testing is critical to therapeutic selection and management of patients with colorectal cancer. In a new multicenter study, researchers compared a new cartridge-based laboratory testing device called the Idylla automated system (Biocartis) to current standard-of-care testing methods.

26 Jun 2020

Researchers discover key signaling pathway in the pathogenesis of Paget's disease

Researchers from the University of California, Irvine, in collaboration with their colleagues from Beijing, China, have gained new insights into the development of poorly understood malignant skin cancers collectively known as Paget's disease.

26 Jun 2020

PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

PrecisionLife’s unique AI platform has found 68 genes associated with risk of developing severe COVID-19 after analysis of the genomes of 929 patients from the UK Biobank who had a severe response to SARS-CoV-2.

26 Jun 2020

Researchers develop unique saliva-based test for COVID-19 detection

University of Saskatchewan researchers are part of two COVID-19-related projects awarded major federal funding today--one to develop a unique saliva-based test for COVID-19 detection and the other to track COVID-19 incidence rates among Canadian dentists.

25 Jun 2020

New Cochrane review assesses the accuracy of COVID-19 antibody tests

Today Cochrane, a global independent organization that reviews evidence from research to inform health decision-making, publishes a review of studies looking at the accuracy of COVID-19 antibody tests.

25 Jun 2020

Research team solves 40-year old mystery in leukemia treatment

A research team led by the University of Kent and Goethe-University Frankfurt am Main, has solved an almost 40-year old mystery in leukemia therapy and the drug nelarabine.

25 Jun 2020

Researchers investigate nelarabine drug for treating leukemia

Acute lymphoblastic leukemia (ALL) is the most common kind of cancer in children. T-ALL, a subtype that resembles T-lymphocytes, can be treated successfully with the drug nelarabine.

24 Jun 2020

Dog-walking intervention may reduce PTSD symptoms in military veterans

The United States is home to more than 21 million military veterans, many of whom have difficulty reintegrating into civilian life.

23 Jun 2020

ACCC releases preliminary results from survey on stage III and IV lung cancer care

The Association of Community Cancer Centers today released preliminary results and an initial set of quality care recommendations from Fostering Excellence in Care and Outcomes in Patients with Stage III and IV NSCLC, an initiative to improve care delivery and outcomes for advanced non-small cell lung cancer (NSCLC) patients.

23 Jun 2020

Differences in accumulation of genetic mutations could help predict lifespan, fertility

Differences in the rate that genetic mutations accumulate in healthy young adults could help predict the remaining lifespan in both sexes and the remaining years of fertility in women, according to the University of Utah Health scientists.

19 Jun 2020

Study finds carboplatin-paclitaxel as the optimal chemotherapy for anal cancer

Up to now, patients with inoperable anal cancer, a rare disease, have not had a standard-of-care treatment; palliative care has been the routine for them.

19 Jun 2020

Discovery of biomarkers that can influence COVID-19 severity

The novel coronavirus, now called the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), is the causative agent of the dreaded coronavirus disease (COVID-19). It was first discovered in Wuhan City, China, back in late December 2019 and has since then spread throughout the globe.

19 Jun 2020

Biomarker News and Research

Further Reading

Cerebrospinal fluid autoantibodies target the brain in some COVID-19 patients

Newly discovered endometrial cancer biomarker enables early detection and treatment

Repeated sampling of FIB-4 score can increase the prediction of future liver cirrhosis

Research shows IQGAP1 as a common target in variants of triple negative breast cancer

Potential new biomarker could improve COVID-19 diagnosis

Scientists discover mechanism involving key protein that predicts cancer progression and relapse

New method for analyzing intact tumor samples to be used for studying COVID-19

Smart MRI scan used for heart disease can help assess aggressive cancers in children

New rapid genomic testing can improve therapy selection for colorectal cancer patients

Researchers discover key signaling pathway in the pathogenesis of Paget's disease

PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

Researchers develop unique saliva-based test for COVID-19 detection

New Cochrane review assesses the accuracy of COVID-19 antibody tests

Research team solves 40-year old mystery in leukemia treatment

Researchers investigate nelarabine drug for treating leukemia

Dog-walking intervention may reduce PTSD symptoms in military veterans

ACCC releases preliminary results from survey on stage III and IV lung cancer care

Differences in accumulation of genetic mutations could help predict lifespan, fertility

Study finds carboplatin-paclitaxel as the optimal chemotherapy for anal cancer

Discovery of biomarkers that can influence COVID-19 severity

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