Clinical Trial News and Research

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People with multiple sclerosis could benefit from a low-fat diet

New research from Oregon Health & Science University suggests that people with multiple sclerosis, or MS, could benefit from a low-fat diet to improve the fatigue that's a debilitating, and often-underappreciated, symptom of the condition.

9 Nov 2023

Bio Farma's Bio-TCV typhoid conjugate vaccine licensed in Indonesia following marketing approval

The International Vaccine Institute (IVI), an international organization with a mission to discover, develop, and deliver safe, effective, and affordable vaccines for global health, and Bio Farma, a biotechnology company based in West Java, Indonesia, announced today that Bio Farma's Bio-TCV typhoid conjugate vaccine (TCV) was licensed in Indonesia following marketing approval from Badan Pengawas Obat dan Makanan (BPOM), the national regulatory authority.

9 Nov 2023

Patients with advanced HER2-positive breast cancer live longer if treated with pyrotinib, trial shows

Patients with HER2-positive breast cancer that has started to spread to other parts of the body survive for longer if they are treated with a new drug called pyrotinib, according to results from the longest follow-up of the PHOEBE randomized clinical trial in China.

8 Nov 2023

12-week daily strawberry intake improves brain health among middle-aged, overweight adults

A new study published in Nutrients shows daily consumption of strawberries for 12 weeks reduced interference in memory and depressive symptoms among middle-aged, overweight adults with self-reported mild cognitive decline.

8 Nov 2023

Study compares the immunogenicity and safety of two SARS-CoV-2 vaccines

The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019. Since then, extensive efforts have been made to develop and evaluate vaccines to combat the virus.

8 Nov 2023

Simultaneous inhibition of two proteins may be a new strategy for tackling triple-negative breast cancer

Researchers at the Centre for Genomic Regulation and Vall d'Hebron Institute of Oncology have shown that the simultaneous inhibition of two different proteins may represent a new strategy for tackling triple-negative breast cancer, the most aggressive and drug-resistant form of breast cancer.

8 Nov 2023

New method could enhance the ability to detect and predict anaphylaxis during oral food challenges

Food allergies can quickly turn a casual meal into a life-threatening situation.

7 Nov 2023

Study reveals how doctors' communication style impacts obesity treatment outcomes

How doctors communicate with patients with obesity can have a significant impact on their weight loss success, according to a new University of Oxford study published today in Annals of Internal Medicine.

7 Nov 2023

Using TNF inhibitors during pregnancy not associated with worse fetal or obstetric outcomes

According to new research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, continuing tumor necrosis factor inhibitors during pregnancy is not associated with worse fetal or obstetric outcomes and may reduce the risk of severe maternal infections during pregnancy (Abstract #0477).

7 Nov 2023

MD Anderson and Jazz Pharmaceuticals collaborate to investigate the potential of zanidatamab in HER2-expressing cancers

The University of Texas MD Anderson Cancer Center and Jazz Pharmaceuticals plc today announced a five-year strategic research collaboration agreement to evaluate zanidatamab, Jazz's investigational HER2-targeted bispecific antibody, in multiple HER2-expressing cancers.

7 Nov 2023

Study shows depression increases disability risk in rheumatoid arthritis sufferers

The interactions between rheumatoid arthritis (RA) and major depressive disorder (MDD).

7 Nov 2023

Probiotics paired with metformin could be a game-changer in type 2 diabetes control

Probiotic supplementation shows promise in managing type 2 diabetes by improving glycemic control, particularly when combined with metformin, although results vary based on probiotic composition and regimen.

6 Nov 2023

New pathologic scoring system could help predict survival in lung cancer patients

A new pathologic scoring system that accurately assesses how much lung tumor is left after a patient receives presurgical cancer treatments can be used to predict survival, according to new research led by investigators at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center and the Mark Foundation Center for Advanced Genomics and Imaging at the Johns Hopkins University.

6 Nov 2023

New analysis of Indonesia Wolbachia trial shows potential for greater dengue reduction

The fight against dengue fever has a new weapon: a mosquito infected with the bacteria Wolbachia, which prevents the spread of the virus.

6 Nov 2023

UTHSC's drug candidate for advanced prostate cancer goes to first clinical trial

A drug candidate developed by researchers at the University of Tennessee Health Science Center for advanced metastatic castration-resistant prostate cancer is now in its first clinical trial.

6 Nov 2023

Three new studies show low-dose atropine can help slow myopia in children

Myopia, or nearsightedness, is at an all-time high among children in the US. Globally, half the population is expected to be nearsighted by 2050.

6 Nov 2023

Targeted drug may offer a new treatment option for patients with relapsed blood cancer

A new targeted drug, studied by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James), may offer a new treatment option for patients with blood cancers, including chronic lymphocytic leukemia (CLL) and Non-Hodgkin lymphoma (NHL) whose disease has stopped responding to standard treatments.

6 Nov 2023

CEPI and University of Oxford launch new project to initiate vaccine development against Junín virus

The Coalition for Epidemic Preparedness Innovations (CEPI) and the University of Oxford today announced the launch of a new project to initiate early development of prototype vaccines against the Junín virus, selected as an exemplar of the Arenavirus family which is responsible for multiple deadly hemorrhagic fevers with epidemic and pandemic potential.

6 Nov 2023

Black men may face an increased risk of prostate cancer than white men at lower PSA levels

Black men in the United States are more likely to develop prostate cancer than white men, and after diagnosis, they're more likely to have advanced disease and to die than white men with the disease.

6 Nov 2023

Researchers announce a new genetic classification system for gastric cancer

Professor Sang Cheul Oh of the Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Professor Sang‑Hee Kang of the Department of Surgery, Korea University's Guro Hospital, and Professor Sun Young Yim of the Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine announced a new genetic classification system for gastric cancer by a multicenter study with the University of Texas MD Anderson Cancer Center.

6 Nov 2023

Clinical Trial News and Research

People with multiple sclerosis could benefit from a low-fat diet

Bio Farma's Bio-TCV typhoid conjugate vaccine licensed in Indonesia following marketing approval

Patients with advanced HER2-positive breast cancer live longer if treated with pyrotinib, trial shows

12-week daily strawberry intake improves brain health among middle-aged, overweight adults

Study compares the immunogenicity and safety of two SARS-CoV-2 vaccines

Simultaneous inhibition of two proteins may be a new strategy for tackling triple-negative breast cancer

New method could enhance the ability to detect and predict anaphylaxis during oral food challenges

Study reveals how doctors' communication style impacts obesity treatment outcomes

Using TNF inhibitors during pregnancy not associated with worse fetal or obstetric outcomes

MD Anderson and Jazz Pharmaceuticals collaborate to investigate the potential of zanidatamab in HER2-expressing cancers

Study shows depression increases disability risk in rheumatoid arthritis sufferers

Probiotics paired with metformin could be a game-changer in type 2 diabetes control

New pathologic scoring system could help predict survival in lung cancer patients

New analysis of Indonesia Wolbachia trial shows potential for greater dengue reduction

UTHSC's drug candidate for advanced prostate cancer goes to first clinical trial

Three new studies show low-dose atropine can help slow myopia in children

Targeted drug may offer a new treatment option for patients with relapsed blood cancer

CEPI and University of Oxford launch new project to initiate vaccine development against Junín virus

Black men may face an increased risk of prostate cancer than white men at lower PSA levels

Researchers announce a new genetic classification system for gastric cancer

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