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Findings suggest new ways to help the immune system fight pancreatic cancer

Findings published today in the journal Science Translational Medicine suggest that a type of white blood cell called tumor associated macrophages that have been deceived by pancreatic cancer cells into not attacking them can be "re-programmed" by a specially designed molecule that activates a protein found on their surfaces.

4 Jul 2019

Hesperos' multi-organ model correctly determine cardiotoxic mechanisms

Hesperos Inc., pioneers of the "human-on-a-chip" in vitro system has announced the use of its innovative multi-organ model to successfully measure the concentration and metabolism of two known cardiotoxic small molecules over time, to accurately describe the drug behavior and toxic effects in vivo.

4 Jul 2019

Immune-boosting compound could make pancreatic cancers susceptible to immunotherapy

Pancreatic cancer is especially challenging to treat – only eight percent of patients are still alive five years after diagnosis.

4 Jul 2019

Researchers synthesize artificial cells to detect histamine

Baking a cake from scratch is a task deemed difficult for many. Constructing an artificial cell-like system from scratch, well that's another story.

3 Jul 2019

Copper compound with potential as therapy for ALS shows further promise

A compound with potential as a treatment for ALS has gained further promise in a new study that showed it improved the condition of mice whose motor neurons had been damaged by an environmental toxin known to cause features of ALS.

2 Jul 2019

Protein Clumps In ALS Neurons Provide Potential Target For New Therapies

Amyotrophic lateral sclerosis is a neurological condition that affects motor neurons -- the nerve cells that control breathing and muscles.

2 Jul 2019

Promising method delivers drug to cancer cells without affecting surrounding cells

RIKEN researchers have developed a promising method to deliver a drug to cancer cells without affecting surrounding tissues, involving a clever combination of an "artificial metalloenzyme" that protects a metal catalyst, and a sugar chain that guides the metalloenzyme to the desired cells.

2 Jul 2019

Ambulance dispatches for minor injuries soar after ACA expansion

By 2016, two years into the expansion of the Affordable Care Act, 17.6 million previously uninsured people around the U.S. had gained health insurance coverage.

29 Jun 2019

Researchers discover 'mystical' psychedelic compound in normal brains

In the past few years, thrill-seekers from Hollywood, Silicon Valley and beyond have been travelling to South America to take part in so-called Ayahuasca retreats.

27 Jun 2019

Low dose of endotoxin could have protective effect on men at risk of acute kidney injury

In a counterintuitive result, researchers found that giving male rats a low dose of the endotoxin lipopolysaccharide (LPS) prior to inducing a model of acute kidney injury (AKI) improved outcomes.

26 Jun 2019

New class of radiopharmaceuticals offer fresh perspective on cancer imaging, theranostics

Research presented at the 2019 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging describes a new class of radiopharmaceuticals, named radiohybrids, that offer a fresh perspective on cancer imaging and radioligand therapy.

26 Jun 2019

New review shows a clear gap in understanding of cancer in LGBTI adolescents

A new systemic review of the literature has shown a clear gap in the understanding of cancer in lesbian, gay, bisexual, transgender and/or intersex adolescents and young adults.

26 Jun 2019

Cannabis ingredient shows promise as potential antibiotic for superbugs

Researches at the University of Queensland in Australia have discovered that a topical formulation containing cannabidiol (CBD) is effective at killing bacterial skin infections.

25 Jun 2019

Atomwise and Enamine launch 10 billion compound virtual drug screening initiative

Atomwise, Inc. today announced the launch of a 10 billion compound AI-powered virtual drug screening initiative, the 10-to-the-10 program, in collaboration with Enamine Ltd., the world’s largest chemical supplier.

25 Jun 2019

Researchers explore new immune checkpoint for head and neck cancer

A checkpoint may delay travelers but it can help give cancer free rein by suppressing the natural immune response that should destroy it, researchers say.

25 Jun 2019

Nanion launches HTS automated patch clamp platform

The SyncroPatch 384i is a giga-ohm seal HTS automated patch clamp platform designed for flexibility, ease-of-use and reliability.

From Nanion Technologies 25 Jun 2019

Timed release of curcumin inhibits cancer cell growth

A Washington State University research team has developed a drug delivery system using curcumin, the main ingredient in the spice turmeric, that successfully inhibits bone cancer cells while promoting growth of healthy bone cells.

21 Jun 2019

Researchers report new way for creating tracers used with medical imaging

In an advance for medical imaging, scientists from University of North Carolina Lineberger Comprehensive Cancer Center have discovered a method for creating radioactive tracers to better track pharmaceuticals in the body as well as image diseases, such as cancer, and other medical conditions.

21 Jun 2019

Creating a physical and genetic map of Cannabis sativa

Scientists have developed a physical and genetic map of Cannabis sativa to facilitate further investigation into the genetic and molecular mechanisms exhibited by this plant.

19 Jun 2019

Study links high number of copies of chromosomal region to chemotherapeutic drug resistance

Researchers at the Bellvitge Biomedical Research Institute, with the participation of collaborators from the Baylor College of Medicine and the University Institute of Oncology of Asturias, publish today in Cancer Research a study where they relate the high number of copies of a chromosomal region with the appearance of resistance to a chemotherapeutic drug.

19 Jun 2019