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Novel LED irradiation system aims to kill microorganisms with UVC light

A novel LED irradiation system developed by the Ferdinand-Braun-Institut aims to kill microorganisms with ultra-short wave UV light - without side effects. Prototype handed over to the Charité for initial testing.

25 May 2020

Can Chlorpromazine help treat COVID-19?

A new research paper published in the journal L'Encéphale in May 2020 reports on the planned ReCoVery Study, which will examine the possibility of repurposing the antipsychotic drug chlorpromazine for the treatment of COVID-19.

25 May 2020

COVID-19 may damage the central nervous system

Researchers at University Hospital Düsseldorf, Germany, have provided important insights into the potential impact that coronavirus disease 2019 (COVID-19) could have on the central nervous system.

21 May 2020

Study pinpoints electrophysiological mechanism behind upper motor neuron disease

Scientists from Northwestern Medicine and the University of Belgrade have pinpointed the electrophysiological mechanism behind upper motor neuron disease, unlocking the door to potential treatments for amyotrophic lateral sclerosis and other neurodegenerative diseases, such as Hereditary Spastic Paraplegia and Primary Lateral Sclerosis.

21 May 2020

Cell-culture based in vitro test systems for antitumor drug screening

As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body.

21 May 2020

Scientists use new model to develop cancer stem cells

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common type of liver cancer is hepatocellular carcinoma (HCC).

21 May 2020

Comprehensive review of clioquinol drug gives valuable insights

CQ is an old drug that was commonly used to treat fungal/protozoal infections of the gastrointestinal tract. Patients in Japan taking it developed subacute myelo-optic neuropathy which resulted in CQ being discontinued for oral use. Recently, extensive research has been done in regards to CQ's use for cancer treatment.

21 May 2020

Texas A&M lab produces 3D-bioprinted bone tissue to benefit bone regeneration

Dr. Akhilesh K. Gaharwar, associate professor, has developed a highly printable bioink as a platform to generate anatomical-scale functional tissues. This study was recently published in the American Chemical Society's Applied Materials and Interfaces.

19 May 2020

Does COVID-19 infect peripheral blood cells?

The emergence of the novel coronavirus outbreak in December 2019 was followed by its spread on a global scale unparalleled in the last 100 years. At present, it has claimed over 322,000 lives the world over, with over 4.88 million cases having tested positive.

19 May 2020

A small, multiphoton microscope enables imaging of cortical layers in freely moving rats

Scientists working at caesar have developed a small head-mounted microscope that allows access to the inner workings of the brain.

19 May 2020

Researchers identify determining factor in luminal cancer cells

The Translational Control of Cell Cycle and Differentiation Lab at IRB Barcelona, led by ICREA researcher Raúl Méndez, has published a study in the journal Science Advances that has identified a key factor in the development of luminal breast cancer.

18 May 2020

Study shows human monoclonal antibodies can effectively neutralize SARS-CoV-2

US researchers have published a proof of concept on the efficacy of human monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in laboratory conditions, as well as their pioneering use in a mouse model. The study is available on the preprint server bioRxiv*.

17 May 2020

New clinical trial to investigate the efficacy of ivermectin against COVID-19

Clínica Universidad de Navarra and the Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, have launched a clinical trial to investigate the efficacy of ivermectin against COVID-19.

14 May 2020

Molecular imaging can help identify treatment response in neuroendocrine tumor patients

A new proof-of-concept study published in the May issue of The Journal of Nuclear Medicine has demonstrated that molecular imaging can be used for identifying early response to 177Lu-DOTATATE treatment in neuroendocrine tumor patients.

14 May 2020

Potential targets discovered for COVID-19 therapy

A team of biochemists and virologists at Goethe University and the Frankfurt University Hospital were able to observe how human cells change upon infection with SARS-CoV-2, the virus causing COVID-19 in people.

14 May 2020

New study explores brain regions that drive the instinct to form lasting bonds

When it comes to forming a lasting bond, our longing for a partner may be as important as - if not more important than - how we react when we're with them, suggests a surprising new brain imaging study published in the Proceedings of the National Academy of Sciences.

13 May 2020

Finding new therapeutic strategies for aggressive T-cell acute lymphoblastic leukemia

Aiming to identify new therapeutic strategies for the aggressive hematological disease T-cell acute lymphoblastic leukemia (T-ALL), Rutgers Cancer Institute of New Jersey resident researcher Daniel Herranz Benito, PhD, along with collaborators from Princeton University, found a new drug that has therapeutic effect against T-ALL by inhibiting SHMT and is complementary to standard-of-care treatment.

12 May 2020

Potential for COVID-19 transmission from human eye

A new study published on the preprint server bioRxiv* in May 2020 reports the presence of ACE2 receptors in the eye at high concentrations. These molecules are the entry points for the SARS-CoV-2 virus that is causing the ongoing COVID-19 pandemic.

12 May 2020

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which constitute clusters of different endocrine cell types.

12 May 2020

Study pinpoints potential neural basis for monogamous reunion

When it comes to forming a lasting bond, our longing for a partner may be as important as--if not more important than--how we react when we're with them, suggests a surprising new brain imaging study published in the Proceedings of the National Academy of Sciences this week.

11 May 2020