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FDA approves two drugs for long-term weight loss

Options are limited in America's battle of the bulge. While diet and exercise can help in the short term, they are frustratingly ineffective in the long run.

12 Feb 2014

Researchers discover that bladder cancer shares genetic similarities with two forms of breast cancer

Researchers at the UNC School of Medicine conducted a comprehensive genetic analysis of invasive bladder cancer tumors to discover that the disease shares genetic similarities with two forms of breast cancer.

12 Feb 2014

Researchers demonstrate new approach to treating muscular dystrophy

Researchers at Washington University School of Medicine in St. Louis have demonstrated a new approach to treating muscular dystrophy. Mice with a form of this muscle-weakening disease showed improved strength and heart function when treated with nanoparticles loaded with rapamycin, an immunosuppressive drug recently found to improve recycling of cellular waste.

12 Feb 2014

IMF announces approval of POMALYST medication in Canada for patients with myeloma

The International Myeloma Foundation - improving the quality of life of myeloma patients while working toward prevention and a cure - said POMALYST (pomalidomide) approval by Health Canada provides patients the most up-to-date oral therapy available for patients who have exhausted all other treatments.

11 Feb 2014

Jazz Pharmaceuticals' Versacloz now commercially available in the U.S. for schizophrenia

Jazz Pharmaceuticals plc today announced U.S. commercial availability of Versacloz (clozapine, USP) oral suspension, the first and only oral suspension clozapine for severely ill treatment-resistant schizophrenia patients or those at risk of recurrent suicidal behavior with schizophrenia or schizoaffective disorder.

11 Feb 2014

Ligand Pharmaceuticals' total revenues for Q4 2013 increase 8% to $14.7 million

Ligand Pharmaceuticals Incorporated today reported financial results for the three and 12 months ended December 31, 2013, and provided an operating forecast and program updates.

11 Feb 2014

Study findings suggest potential targets for treating HCV

The hepatitis C virus (HCV) has a previously unrecognized tactic to outwit antiviral responses and sustain a long-term infection. It also turns out that some people are genetically equipped with a strong countermeasure to the virus' attempt to weaken the attack on it.

11 Feb 2014

Researchers introduce unique micro-robotic technique for tissue engineering and 3D printing

Researchers at Brigham and Women's Hospital and Carnegie Mellon University have introduced a unique micro-robotic technique to assemble the components of complex materials, the foundation of tissue engineering and 3D printing.

11 Feb 2014

Researchers examine link between alcohol consumption and breast cancer development

New research looking at the biological process involved in breast cancer development has strengthened the argument for a potential link between alcohol consumption and the disease.

From The University of Manchester 11 Feb 2014

Gilead submits NDA to FDA for fixed-dose combination of ledipasvir and sofosbuvir for hepatitis C infection

Gilead Sciences, Inc. (Nasdaq: GILD) today announced that the company has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for a once-daily fixed-dose combination of the NS5A inhibitor ledipasvir (LDV) 90 mg and the nucleotide analog polymerase inhibitor sofosbuvir (SOF) 400 mg for the treatment of chronic hepatitis C genotype 1 infection in adults.

11 Feb 2014

Drug used for treating breast cancer also kills fungal disease

Tamoxifen, a drug currently used to treat breast cancer, also kills a fungus that causes a deadly brain infection in immunocompromised patients. The findings, which could lead to new treatments for a disease that kills more HIV/AIDS patients than tuberculosis, appear in mBio-, the online open-access journal of the American Society for Microbiology (ASM.)

11 Feb 2014

Engineers place tiny synthetic motors inside live human cells

For the first time, a team of chemists and engineers at Penn State University have placed tiny synthetic motors inside live human cells, propelled them with ultrasonic waves and steered them magnetically. It's not exactly "Fantastic Voyage," but it's close. The nanomotors, which are rocket-shaped metal particles, move around inside the cells, spinning and battering against the cell membrane.

11 Feb 2014

Mayo Clinic researchers shed light on new mechanism by which prostate cancer develops in men

Mayo Clinic researchers have shed light on a new mechanism by which prostate cancer develops in men. Central to development of nearly all prostate cancer cases are malfunctions in the androgen receptor - the cellular component that binds to male hormones.

11 Feb 2014

ASTRO, SSO guideline focuses on reducing ipsilateral breast tumor recurrence in stages I, II breast cancer

The American Society for Radiation Oncology (ASTRO) and the Society of Surgical Oncology (SSO) are pleased to announce the publication of the consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer.

11 Feb 2014

Combination of infused vitamin C and conventional chemotherapy drugs stops ovarian cancer

Scientists at the University of Kansas Medical Center have determined that high doses of vitamin C, administered intravenously with traditional chemotherapy, helped kill cancer cells while reducing the toxic effects of chemotherapy for some cancer patients.

10 Feb 2014

UCLA researchers awarded $6M grant to explore new therapies for spinal-cord injuries

The National Institute of Biomedical Imaging and Bioengineering has awarded UCLA researchers Dr. Daniel Lu (Brentwood) and Dr. Reggie Edgerton (Bel Air) a $6 million, five-year grant to explore new therapies for the approximately 273,000 Americans living with spinal-cord injuries. Some 12,000 Americans suffer such injuries each year.

10 Feb 2014

Two oncogenes work together to sustain population of cells in lung squamous cell carcinoma

Patients with a common form of lung cancer — lung squamous cell carcinoma — have very few treatment options. That situation may soon change.

10 Feb 2014

Pancreatic stellate cells help pancreatic cancer grow and spread in cell hijack method

Pancreatic stellate cells, which normally aid tissue repair, unwittingly help pancreatic cancer grow and spread in a method of 'cell hijack' only seen before in brain and breast cancer, according to new research from Queen Mary University of London.

10 Feb 2014

Findings may help physicians choose precise treatments for women with advanced breast cancer

The first large-scale study testing all the DNA—the entire genome—of tumour cells from more than 400 women with advanced breast cancer has identified individuals with a good chance of benefiting from specific treatments already being tested in clinical trials.

10 Feb 2014

Study examines risks and benefits of testosterone therapy for older men

According to a statement issued today by the Endocrine Society, the risks and benefits of testosterone therapy for older men with declining levels of the hormone need to be fully evaluated.

10 Feb 2014

Therapy News and Research

FDA approves two drugs for long-term weight loss

Researchers discover that bladder cancer shares genetic similarities with two forms of breast cancer

Researchers demonstrate new approach to treating muscular dystrophy

IMF announces approval of POMALYST medication in Canada for patients with myeloma

Jazz Pharmaceuticals' Versacloz now commercially available in the U.S. for schizophrenia

Ligand Pharmaceuticals' total revenues for Q4 2013 increase 8% to $14.7 million

Study findings suggest potential targets for treating HCV

Researchers introduce unique micro-robotic technique for tissue engineering and 3D printing

Researchers examine link between alcohol consumption and breast cancer development

Gilead submits NDA to FDA for fixed-dose combination of ledipasvir and sofosbuvir for hepatitis C infection

Drug used for treating breast cancer also kills fungal disease

Engineers place tiny synthetic motors inside live human cells

Mayo Clinic researchers shed light on new mechanism by which prostate cancer develops in men

ASTRO, SSO guideline focuses on reducing ipsilateral breast tumor recurrence in stages I, II breast cancer

Combination of infused vitamin C and conventional chemotherapy drugs stops ovarian cancer

UCLA researchers awarded $6M grant to explore new therapies for spinal-cord injuries

Two oncogenes work together to sustain population of cells in lung squamous cell carcinoma

Pancreatic stellate cells help pancreatic cancer grow and spread in cell hijack method

Findings may help physicians choose precise treatments for women with advanced breast cancer

Study examines risks and benefits of testosterone therapy for older men

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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