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Study identifies key immune cells that could protect the brain after cardiac arrest

Despite improvements in CPR and rates of getting patients to the hospital, only about 10 percent of people ultimately survive after out-of-hospital cardiac arrest (OHCA), translating to about 300,000 deaths per year in the United States.

5 Dec 2024

Coral-inspired bone graft could transform treatment for bone defects

Researchers at Swansea University have developed a revolutionary bone graft substitute inspired by coral which not only promotes faster healing but dissolves naturally in the body after the repair is complete.

5 Dec 2024

Ketone body β-hydroxybutyrate restores protein balance and targets Alzheimer’s-linked aggregates

Scientists identify β-hydroxybutyrate as a key regulator of protein solubility, offering a novel pathway to combat neurodegeneration in aging and Alzheimer’s disease.

4 Dec 2024

Glyphosate exposure linked to lasting brain inflammation

The human brain is an incredibly adaptable organ, often able to heal itself even from significant trauma.

4 Dec 2024

Immune cells play a key role in movement control and metabolic balance

Immune cells have a surprising and critical role in controlling movement and bridging neural activity with metabolic demands, concludes a groundbreaking study published in Nature by researchers at the University of Copenhagen and Imperial College London.

4 Dec 2024

Women with infertility have higher risk of developing systemic autoimmune diseases

Women who experience infertility but do not use fertility treatments have a higher risk of developing a group of conditions called systemic autoimmune rheumatic diseases (SARD) in the nine years after a naturally conceived birth compared to women without fertility problems.

4 Dec 2024

New approach to understanding chronic inflammation could lead to better cancer therapies

A recently published study led by Wayne State University on a new approach to understanding chronic inflammation could lead to new advancements in the treatment of many debilitating medical conditions, including cancer.

4 Dec 2024

Common farming pesticides linked to rheumatoid arthritis

Exposure to specific pesticides is linked to increased rheumatoid arthritis risk, with notable dose-response trends for malathion and carbofuran among older licensed applicators in the Agricultural Health Study.

4 Dec 2024

New AI tool maps millions of CD8+ T cells to advance disease research

The scAtlasVAE model integrates scRNA-seq data to create a CD8+ T cell atlas, enhancing understanding of immune responses in inflammation and cancer.

4 Dec 2024

Cancer therapy may raise heart attack and stroke risks by disrupting immune regulation in arteries

Immune checkpoint inhibitors may heighten cardiovascular risks by altering immune interactions in atherosclerotic plaques, particularly in diabetic patients.

4 Dec 2024

Exploring the potential of MSCs in cancer therapy

A new review was published in Oncotarget's Volume 15 on November 22, 2024, entitled "Mesenchymal stem cells – the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists."

4 Dec 2024

Disrupted sleep-wake rhythms linked to liver disease progression

The prevalence of MASLD (metabolic dysfunction-associated steatotic liver disease) is exploding in most regions of the world, boosted by increased obesity and sedentary lifestyles. MASLD (formerly known as non-alcoholic fatty liver disease) is already the most common liver disorder: it affects 30% of adults and between 7% and 14% of children and adolescents, and this prevalence is predicted to rise to more than 55% of adults by 2040.

4 Dec 2024

SARS-CoV-2 spike protein found lingering in brain regions

Researchers find that SARS-CoV-2 spike protein persists in the skull-meninges-brain axis, driving neuroinflammation, neurodegeneration, and heightened vulnerability to brain injuries.

3 Dec 2024

Nanozyme breakthrough offers new hope for viral pneumonia treatment

A recent study in Nature Materials introduces an inhalable nanozyme treatment for viral pneumonia, showing promising results in reducing inflammation and viral load in various mouse models. The nanozyme, CeTA-K1tkP, demonstrates broad-spectrum effects and biocompatibility, offering a potential new approach to treating pneumonia and other inflammatory conditions.

3 Dec 2024

How carrageenan affects insulin resistance

A randomized controlled trial found that carrageenan, a common food additive, may cause subclinical inflammation and insulin resistance in overweight individuals, mediated by gut permeability and inflammation. Effects were linked to BMI but not observed in non-overweight participants during short-term exposure.

3 Dec 2024

Inflammation and organ damage in severe COVID-19 tied to mitochondrial dysfunction

Severe COVID-19 arises in part from the SARS-CoV-2 virus's impact on mitochondria, tiny oxygen-burning power plants in cells, which can help trigger a cascade of organ- and immune system-damaging events, suggests a study by investigators at Weill Cornell Medicine, Johns Hopkins Medicine, Children's Hospital of Philadelphia, and the University of Pittsburgh School of Medicine, along with other members of the COVID-19 International Research Team.

3 Dec 2024

Minimally invasive procedure provides relief for knee osteoarthritis sufferers

A minimally invasive procedure provides significant relief from knee pain and may prevent the need for knee replacement surgery in people with osteoarthritis, according to a study being presented this week at the annual meeting of the Radiological Society of North America (RSNA).

3 Dec 2024

Bedfont® Scientific Limited Brings Cutting-Edge Respiratory and Gastrointestinal Diagnostic Solutions to Saudi Arabia with New Registration

With the launch of NObreath® FeNO and Gastrolyzer® devices, Bedfont® and Tebaba Medical Services are advancing breath analysis technology in the Middle East.

From NObreath 3 Dec 2024

Ketone metabolism redefines protein quality control in aging brains

Ketone bodies, produced by the body to provide fuel during fasting, have roles in regulating cellular processes and aging mechanisms beyond energy production. Research at the Buck Institute shows that ketone bodies can best be understood as powerful signaling metabolites affecting brain function in aging and Alzheimer's disease.

3 Dec 2024

Fas-p53 pathway drives metabolic dysfunction and obesity-linked insulin resistance

Researchers unveil Fas-p53 axis as a key regulator in adipocyte metabolism, linking it to obesity and insulin sensitivity through energy expenditure and inflammation pathways.

3 Dec 2024

Inflammation News and Research

Study identifies key immune cells that could protect the brain after cardiac arrest

Coral-inspired bone graft could transform treatment for bone defects

Ketone body β-hydroxybutyrate restores protein balance and targets Alzheimer’s-linked aggregates

Glyphosate exposure linked to lasting brain inflammation

Immune cells play a key role in movement control and metabolic balance

Women with infertility have higher risk of developing systemic autoimmune diseases

New approach to understanding chronic inflammation could lead to better cancer therapies

Common farming pesticides linked to rheumatoid arthritis

New AI tool maps millions of CD8+ T cells to advance disease research

Cancer therapy may raise heart attack and stroke risks by disrupting immune regulation in arteries

Exploring the potential of MSCs in cancer therapy

Disrupted sleep-wake rhythms linked to liver disease progression

SARS-CoV-2 spike protein found lingering in brain regions

Nanozyme breakthrough offers new hope for viral pneumonia treatment

How carrageenan affects insulin resistance

Inflammation and organ damage in severe COVID-19 tied to mitochondrial dysfunction

Minimally invasive procedure provides relief for knee osteoarthritis sufferers

Bedfont® Scientific Limited Brings Cutting-Edge Respiratory and Gastrointestinal Diagnostic Solutions to Saudi Arabia with New Registration

Ketone metabolism redefines protein quality control in aging brains

Fas-p53 pathway drives metabolic dysfunction and obesity-linked insulin resistance

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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