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Viruses modify host cellular machinery to produce high amounts of viral progeny

The study, published in Nature Communications, shows a new mechanism whereby viruses modify cellular machinery so that it can better read the instructions in the genome of the invading virus.

29 Aug 2022

Microscopy technique enables visualization of unseen nanostructures within cells and tissues

Inside a living cell, proteins and other molecules are often tightly packed together. These dense clusters can be difficult to image because the fluorescent labels used to make them visible can't wedge themselves in between the molecules.

29 Aug 2022

FAU and Tel Aviv researchers receive grant to tackle Alzheimer’s-related mood disorders

Alzheimer's disease (AD) is the most common type of dementia affecting an estimated 6.3 million Americans age 65 and older. Without the development of medical breakthroughs to prevent, treat, slow or cure AD that number could grow to 13.8 million by 2060.

29 Aug 2022

Researchers receive $1.2 million Keck Foundation grant to find molecules for targeting the 'undruggable proteome'

The W.M. Keck Foundation has awarded a $1.2 million grant to medicinal chemistry and computational biology researchers at the University of Kansas and the University of Chicago focused on addressing a long-unresolved problem in biomedical research - finding molecules able to target the "undruggable proteome."

29 Aug 2022

TTUHSC scientist receives U.S. patent to produce novel nanoantibiotics

According to the Centers for Disease Control and Prevention, more than 2.8 million Americans contract antibiotic-resistant bacterial infections each year, and approximately 35,000 of those patients do not survive their infection.

29 Aug 2022

Evolution can favor flexible proteins, research suggests

When you think of proteins – the enzymes, signaling molecules, and structural components in every living thing – you might think of single strands of amino acids, organized like beads on a string.

26 Aug 2022

Researchers develop a protein thermal shift chip for COVID-19

Announcing a new publication for Acta Materia Medica journal. Traditional protein chips are based on solid chips and cannot enable drug and target screening in a label-free manner.

26 Aug 2022

Discovery may lead to the development of new systems of antifungal drugs

Mycosis is an infectious disease caused by parasitic mold or yeast and treated with an antifungal, a subgroup of antibiotics.

26 Aug 2022

New approach using CRISPR can engineer massive quantities of cells for therapeutic applications

A new variation of the CRISPR-Cas9 gene editing system makes it easier to re-engineer massive quantities of cells for therapeutic applications.

25 Aug 2022

COVID-19 pandemic: An epidemiological update

Epidemics and pandemics have been frightening the human chase again and again. SARS, H1N1, Ebola, and more have exposed their real face in the past, but with every such outbreak.

25 Aug 2022

Using AI to foster productivity in pharmaceutical research and development

As part of our SLAS Europe 2022 coverage, we speak to Sree Vadlamudi from Iktos, about how we can adopt AI to help foster productivity within pharmaceutical research.

From Society for Laboratory Automation and Screening (SLAS) 25 Aug 2022

Optimized human small intestinal organoids can help better study the functioning of small intestines

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids – miniature versions of the small intestine.

24 Aug 2022

Glucokinase activator AZD1656 shows potential benefit for diabetics with moderate to severe COVID-19

A new study examines the potential benefit of the glucokinase activator molecule AZD1656 in the ARCADIA trial.

23 Aug 2022

Surprising culprit contributes significantly to the brain destruction after stroke or TBI

In the aftermath of a stroke or TBI, a group of amino acids that typically support brain function contribute significantly to the brain destruction that can follow both these injuries, scientists report.

23 Aug 2022

Common molecular tool for DNA labelling shows unexpected anticancer properties

Scientists at the UNC School of Medicine have made the surprising discovery that a molecule called EdU, which is commonly used in laboratory experiments to label DNA, is in fact recognized by human cells as DNA damage, triggering a runaway process of DNA repair that is eventually fatal to affected cells, including cancer cells.

23 Aug 2022

Super-resolution imaging reveals how disease causes cells to reorder their DNA incorrectly

Imagine you're trying to do a job and all of the information you need to do it is in a few books at the library.

22 Aug 2022

Scientists discover a mechanism used by insects in the development and regeneration of wings

The first mutation of the wingless gene was found by accident in Drosophila in the 1970s, following the observation of flies that did not possess wings, hence its name.

22 Aug 2022

Scientists begin phase 2 clinical trials of lupus pill

Lupus is an autoimmune disease that attacks organs and can be fatal. There's no cure, so current treatments aim to limit damage and ameliorate symptoms.

22 Aug 2022

New discovery helps explain the dynamics underlying liver damage in type 2 diabetes and obesity

When fat accumulates in the liver, the immune system may assault the organ. A new study from Weill Cornell Medicine researchers identifies the molecule that trips these defenses, a discovery that helps to explain the dynamics underlying liver damage that can accompany type 2 diabetes and obesity.

19 Aug 2022

Sanders-Brown director receives $1.5 million grant to advance research on Alzheimer's treatment

Linda J. Van Eldik, Ph.D., director of the University of Kentucky Sanders-Brown Center on Aging, is part of a $1.5 million grant to help further research into a possible treatment for Alzheimer's disease.

19 Aug 2022

Molecule News and Research

Viruses modify host cellular machinery to produce high amounts of viral progeny

Microscopy technique enables visualization of unseen nanostructures within cells and tissues

FAU and Tel Aviv researchers receive grant to tackle Alzheimer’s-related mood disorders

Researchers receive $1.2 million Keck Foundation grant to find molecules for targeting the 'undruggable proteome'

TTUHSC scientist receives U.S. patent to produce novel nanoantibiotics

Evolution can favor flexible proteins, research suggests

Researchers develop a protein thermal shift chip for COVID-19

Discovery may lead to the development of new systems of antifungal drugs

New approach using CRISPR can engineer massive quantities of cells for therapeutic applications

COVID-19 pandemic: An epidemiological update

Using AI to foster productivity in pharmaceutical research and development

Optimized human small intestinal organoids can help better study the functioning of small intestines

Glucokinase activator AZD1656 shows potential benefit for diabetics with moderate to severe COVID-19

Surprising culprit contributes significantly to the brain destruction after stroke or TBI

Common molecular tool for DNA labelling shows unexpected anticancer properties

Super-resolution imaging reveals how disease causes cells to reorder their DNA incorrectly

Scientists discover a mechanism used by insects in the development and regeneration of wings

Scientists begin phase 2 clinical trials of lupus pill

New discovery helps explain the dynamics underlying liver damage in type 2 diabetes and obesity

Sanders-Brown director receives $1.5 million grant to advance research on Alzheimer's treatment

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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