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Northwestern scientists continue to advance the understanding of COVID-19

As the COVID-19 pandemic enters its third year, Northwestern Medicine scientists continue to help advance the understanding of the disease and its impact, from investigating antibody protection against COVID-19 reinfection to elevating women in academic research and highlighting racial and ethnic disparities in COVID-19 hospital mortality in Illinois.

28 Mar 2022

Evaluating severity of influenza infection in ferrets with COVID-19 history

In a new study, researchers investigated the effect of SARS-CoV-2 exposure on the severity of influenza in ferrets.

28 Mar 2022

The potential risk of SARS-CoV-2 transmission through fomites contaminated by hospitalized COVID-19 patients

Researchers evaluated the potential risk of SARS-CoV-2 transmission through fomites contaminated by hospitalized COVID-19 patients during coughing or intense moistening with saliva.

28 Mar 2022

Study investigates recombinant SARS-CoV-2 variants in immunocompromised individuals

Researchers identified the recombination of two SARS-CoV-2 variants.

28 Mar 2022

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

A new research paper published as an early release manuscript in the Nature Medicine journal compares the sensitivity of this strain as well as the earlier Delta and the newer BA.2 to therapeutic mAbs.

27 Mar 2022

U.S. traveler-based genomic surveillance provided early SARS-CoV-2 variant detection

Researchers discuss their efforts to detect SARS-CoV-2 and its variants in travelers entering the United States.

27 Mar 2022

Biologists discover gene deletion behind abnormality in blood cancer cells

The mystery is being unraveled of why the control centers, or nuclei, of certain blood cancer cells have a distinctly odd shape.

27 Mar 2022

Study finds methylene blue is a low-micromolar inhibitor of the the SARS-CoV-2 spike protein and ACE2 interaction

A new study has focussed on screening and identification of possible SMIs of this PPI for COVID-19.

25 Mar 2022

Algae found to inhibit SARS-CoV-2 infection in vitro

A new study demonstrated that dry algal powders inhibit SARS-CoV-2 in vitro.

25 Mar 2022

Understanding a New Mutation in Pediatric AML

News-Medical speaks to Dr. Jeffery Klco about acute myeloid leukemia (AML) and his recent research that is helping us to understand a new mutation in pediatric AML.

25 Mar 2022

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

A new study evaluated the N terminal domain of the SARS-CoV-2 nucleocapsid protein. It presented the targeted characteristics for selective ribonucleic acid identification by SARS-CoV-2 N in its 5'-genomic end.

24 Mar 2022

New SARS-CoV-2 Omicron-Delta recombinant virus identified in the US

Researchers reported a novel SARS-CoV-2 Omicron and Delta recombinant virus in the United States.

24 Mar 2022

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

A recent study demonstrated that RNA interference could prophylactically protect against SARS-CoV-2.

24 Mar 2022

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

Scientists from the United States have recently assessed the evolutionary success of mutations accumulated across severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome. They have observed that the positively-selected mutations in the viral spike S1 subunit are primarily responsible for adaptive evolution. This indicates that the virus may undergo antigenic drift.

23 Mar 2022

Recombinant SARS-CoV-2 Delta-Omicron variant identified in the United States

There is likely recombination of genome sequences between the SARS-CoV-2 Delta and Omicron variants in their spike (S) protein.

23 Mar 2022

Researchers find two gene variants linked to accelerated aging in childhood cancer survivors

Scientists from St. Jude Children's Research Hospital have identified variants in two genes that are associated with accelerated aging in childhood cancer survivors. Their research looked at the difference between their biological age and chronological age.

23 Mar 2022

Genomic sequencing reveals unique pattern of SARS-CoV-2 Epsilon emergence in Alaska

Researchers used genomic sequencing to examine SARS-CoV-2 genomes from Alaska, United States, between December 2020 and June 2021.

23 Mar 2022

Researchers discover a compound that reduces epileptic seizures

Researchers studying epileptic seizures of the temporal lobe – the most common type of epilepsy – discovered a compound that reduces seizures in the hippocampus, a brain region where many such seizures originate.

22 Mar 2022

BGI discovery could pave the way for advances in organ regeneration and synthetic biology

In a world-first, scientists from BGI-Research, Chinese Academy of Sciences, and a group of partners published a study in Nature, announcing the discovery of a transgene-free, rapid, and controllable method to convert pluripotent stem-cells into bona fide 8-cell totipotent embryo-like cells, paving the way for advances in organ regeneration and synthetic biology.

22 Mar 2022

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

A new study investigated the interactions between SARS-CoV-2 proteins and viral and host ribonucleic acid in virus-infected cells.

22 Mar 2022

Genomic News and Research

Northwestern scientists continue to advance the understanding of COVID-19

Evaluating severity of influenza infection in ferrets with COVID-19 history

The potential risk of SARS-CoV-2 transmission through fomites contaminated by hospitalized COVID-19 patients

Study investigates recombinant SARS-CoV-2 variants in immunocompromised individuals

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

U.S. traveler-based genomic surveillance provided early SARS-CoV-2 variant detection

Biologists discover gene deletion behind abnormality in blood cancer cells

Study finds methylene blue is a low-micromolar inhibitor of the the SARS-CoV-2 spike protein and ACE2 interaction

Algae found to inhibit SARS-CoV-2 infection in vitro

Understanding a New Mutation in Pediatric AML

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

New SARS-CoV-2 Omicron-Delta recombinant virus identified in the US

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

Recombinant SARS-CoV-2 Delta-Omicron variant identified in the United States

Researchers find two gene variants linked to accelerated aging in childhood cancer survivors

Genomic sequencing reveals unique pattern of SARS-CoV-2 Epsilon emergence in Alaska

Researchers discover a compound that reduces epileptic seizures

BGI discovery could pave the way for advances in organ regeneration and synthetic biology

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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