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Researchers harness plasma-produced gas to activate plant immunity against wide-spread diseases

The flash of lightning and the dance of auroras contain a fourth state of matter known as plasma, which researchers have harnessed to produce a gas that may activate plant immunity against wide-spread diseases.

19 Aug 2022

Johns Hopkins Medicine researchers challenge the prevailing belief on how nasal cells process scent

Johns Hopkins Medicine researchers say they have evidence to potentially overturn a prevailing belief in a type of important signaling within cells.

18 Aug 2022

Simple technique could be a powerful solution for disposing ‘forever chemicals’

PFAS, a group of manufactured chemicals commonly used since the 1940s, are called "forever chemicals" for a reason.

18 Aug 2022

Therapeutic target for several metabolic diseases may help fight Alzheimer’s disease

In the recent popular Korean TV series "The Light in Your Eyes," many viewers emphasized with the main character suffering from Alzheimer's disease.

18 Aug 2022

New strategies to enhance the survival of children with neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN (MYCN amplified), the primary driver of neuroblastoma and its resistance to therapy.

18 Aug 2022

Innovative technology revels the impact of environmental conditions on RNA structures in living cells

The impact of environmental conditions on the dynamic structures of RNAs in living cells has been revealed by innovative technology developed by researchers at the John Innes Centre.

17 Aug 2022

Acid ceramidase is a SARS-CoV-2 host factor, study says

Fluoxetine, a common antidepressant, inhibits the SARS-CoV-2 coronavirus in cell cultures and in preparations from human lung tissue. This was demonstrated by researchers at Julius-Maximilians-Universität (JMU) Würzburg in the summer of 2020. However, the mechanism of this inhibition was utterly unclear, so the teams continued their research.

17 Aug 2022

Study identifies the link between a gene variant and protection against coronary atherosclerosis

The protective effect of the newly discovered variant against coronary heart disease is likely to be caused by the below-average arterial stiffness of variant carriers.

17 Aug 2022

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

Researchers at the University of California San Diego have received a $1.3 million grant from the W. M. Keck Foundation for a project that could help scientists better understand the role misfolded tau proteins play in causing neurodegenerative diseases like dementia, which may lead to more effective drug therapies.

16 Aug 2022

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

New research led by scientists at Mass Eye and Ear and Brigham and Women's Hospital, member hospitals of Mass General Brigham, reveals the role that a genetic variant associated with Alzheimer's disease, APOE4, plays in protecting against glaucoma.

16 Aug 2022

UT Southwestern's cryo-EM images shed light on the mechanisms behind Wnt signaling activation

Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and cancer and crucial for Wnt signaling activation.

16 Aug 2022

Next generation mRNA vaccines exhibit excellent protective and therapeutic effects

Researchers around the world have been working for years on developing vaccines against different types of cancer, but without much success. Now, Tufts School of Engineering researchers think they have found one that does work. They have devised a method of targeting cancer in mice with a vaccine that is so strong and precise, it eliminates tumors and even prevents their recurrence.

16 Aug 2022

Study paves new way to develop a predictive biomarker for TRAIL therapy

A cytokine named TRAIL binds to TRAIL receptors and kills cancer cells, but not normal cells. Therefore, various anticancer drugs targeting TRAIL receptors have been developed and gained great attention as a promising cancer therapeutics, but a certain population of cancer patients does not respond to the therapy.

15 Aug 2022

Single-dose therapeutic interfering particle lowers SARS-CoV-2 pathogenesis and shedding among hamsters

Researchers reported that a single-dose therapeutic interfering particle (TIP) lowers SARS-CoV-2 pathogenesis and shedding among hamsters.

15 Aug 2022

Elevated acetate levels reprogram gut microbiota during alcohol intake

Chronic alcohol use is a major cause of liver damage and death: Approximately 30,000 persons in the United States die annually from alcoholic liver diseases, such as cirrhosis.

11 Aug 2022

UIC focuses on developing an antiviral therapy for filoviruses

Researchers at the University of Illinois Chicago are working with the National Institutes of Health and researchers from across the country to establish a center for antiviral drug development for pandemic-level viruses, including Ebola and SARS-CoV-2, the virus that causes COVID-19.

11 Aug 2022

Repurposed drug shows promise as potential new treatment for motor neuron disease

A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND), according to a new study.

11 Aug 2022

Interferon beta reduces binding of three components to RBCs, study finds

Drugs called interferon betas are common treatments for multiple sclerosis (MS), reducing relapses and slowing motor function decline. Interferon beta, a protein known to contain a zinc binding pocket, is thought to reduce proinflammatory molecules and even increase production of anti-inflammatory species in MS patients.

11 Aug 2022

Gene expression in male and female brains become more similar with age, study says

When male and female fruit flies age, their brains become desexualized. Age-related changes take place in both sexes, but the male brain becomes feminized to a larger extent than the female brain becomes masculinized. This is the conclusion of a study performed by a research group at Linköping University. The findings are published in the journal Proceedings of the Royal Society of London B.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Molecule News and Research

Researchers harness plasma-produced gas to activate plant immunity against wide-spread diseases

Johns Hopkins Medicine researchers challenge the prevailing belief on how nasal cells process scent

Simple technique could be a powerful solution for disposing ‘forever chemicals’

Therapeutic target for several metabolic diseases may help fight Alzheimer’s disease

New strategies to enhance the survival of children with neuroblastoma

Innovative technology revels the impact of environmental conditions on RNA structures in living cells

Acid ceramidase is a SARS-CoV-2 host factor, study says

Study identifies the link between a gene variant and protection against coronary atherosclerosis

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

UT Southwestern's cryo-EM images shed light on the mechanisms behind Wnt signaling activation

Next generation mRNA vaccines exhibit excellent protective and therapeutic effects

Study paves new way to develop a predictive biomarker for TRAIL therapy

Single-dose therapeutic interfering particle lowers SARS-CoV-2 pathogenesis and shedding among hamsters

Elevated acetate levels reprogram gut microbiota during alcohol intake

UIC focuses on developing an antiviral therapy for filoviruses

Repurposed drug shows promise as potential new treatment for motor neuron disease

Interferon beta reduces binding of three components to RBCs, study finds

Gene expression in male and female brains become more similar with age, study says

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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