Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Clinically relevant biomarker strategies in drug development

In this interview, NewsMedical speaks with Dr. Justin Devine and Dr. Nicholas Woudberg about biomarkers, their importance for drug development as well as the potential they have when it comes to machine learning.

From Synexa Life Sciences 9 Jan 2023

At-home saliva test to diagnose adrenal insufficiency makes a difference to patients' health

A study into the use of an at-home test which uses saliva rather than blood to diagnose adrenal insufficiency, which has been developed by scientists at the University of Sheffield with funding from the National Institute for Health and Care Research, and tested in Sheffield endocrine patients at Sheffield Teaching Hospitals NHS Foundation Trust, is making a difference to the health of patients and could reduce time to diagnosis.

6 Jan 2023

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

A new research paper was published in Oncotarget's Volume 13 on December 20, 2022, entitled, "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression."

6 Jan 2023

Postoperative restrictive opioid protocols reduce long-term opioid use

Research at Roswell Park Comprehensive Cancer Center shows that putting a three-day limit on opioid prescriptions to treat surgical pain after hospital discharge reduces the number of patients who become chronic opioid users without compromising pain relief or recovery.

5 Jan 2023

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have found that measuring activation of immune-system B cells may be better than measuring either T-cell activation or the total number of immune cells in and around a tumor, called tumor-infiltrating lymphocytes (TILs), in predicting whether HER2-positive breast cancer responds to treatment.

5 Jan 2023

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

Insilico Medicine, a clinical stage, end-to-end artificial intelligence (AI)-driven drug discovery company, held the launch ceremony for Life Star – a 6th generation Intelligent Robotics Drug Discovery Laboratory – in Suzhou BioBAY Industrial Park on Dec. 29.

5 Jan 2023

PhoreMost and Boehringer Ingelheim enter multi-project drug discovery collaboration

PhoreMost Limited, the UK-based biopharmaceutical company dedicated to drugging ‘undruggable’ disease targets, today announced it has entered into a multi-project drug discovery collaboration with Boehringer Ingelheim, one of the world-leading pharmaceutical companies developing innovative therapies for diseases with unsatisfactory treatments.

From PhoreMost 5 Jan 2023

Study shows the potential of a game-changing drug to treat upper urinary tract urothelial cancers

A team from 15 U.S. medical centers led by UT Southwestern Simmons Cancer Center researchers has performed the first analysis of a potentially game-changing drug to treat upper urinary tract urothelial cancers.

4 Jan 2023

Precise 3D imaging can help measure radiation during cancer treatment

Radiation, used to treat half of all cancer patients, can be measured during treatment for the first time with precise 3D imaging developed at the University of Michigan.

3 Jan 2023

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with poor prognosis and limited treatment options.

3 Jan 2023

Researchers identify novel gene mechanism in most aggressive kidney cancers

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway with loss of the tuberous sclerosis complex (TSC) tumor suppressor gene.

3 Jan 2023

New method records gene activity patterns and presence of proteins across tissues

A new method can illuminate the identities and activities of cells throughout an organ or a tumor at unprecedented resolution, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center.

2 Jan 2023

UKB resident awarded the C. E. Alken Prize for outstanding scientific uro-oncological research

Dr. Niklas Klümper, resident at the Clinic for Urology and working group leader at the Institute for Experimental Oncology at the University Hospital Bonn (UKB), was awarded the C. E. Alken Prize in recognition of his outstanding scientific uro-oncological work.

30 Dec 2022

Delaying antibiotic treatment does not reduce survival chances in cancer patients with neutropenic fever

In cancer patients with neutropenic fever, delaying antibiotic treatment past 60 minutes from the time of fever detection does not reduce the short-term chance of survival, according to a study in the American Journal of Medical Quality.

30 Dec 2022

Predictive models using serum miRNAs may offer objective criteria for referral to early palliative care services

A new research paper was published in Oncotarget's Volume 13 on December 17, 2022, entitled, "Serum microRNAs as new criteria for referral to early palliative care services in treatment-naïve advanced cancer patients."

29 Dec 2022

Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

A new research paper was published in Oncotarget's Volume 13 on December 17, 2022, entitled, "The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies."

29 Dec 2022

NCI-led clinical trial results in the first approval of a treatment for advanced alveolar soft part sarcoma

A clinical trial led by the National Cancer Institute (NCI), part of the National Institutes of Health, has resulted in the first approval of a treatment for advanced alveolar soft part sarcoma (ASPS).

28 Dec 2022

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Insilico Medicine ("Insilico"), a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that the company's drug discovery team has nominated a preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy utilizing its end-to-end Pharma.AI platform.

27 Dec 2022

Researchers discover a protein linked with the onset of anthracycline-associated cardiac toxicity

Anthracyclines are a class of chemotherapies effective in treating many forms of cancer, including leukemias, lymphomas and breast cancer.

27 Dec 2022

Cell-based method can predict how breast cancer patients will respond to treatments

Researchers at Karolinska Institutet in Sweden have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular treatment or not.

27 Dec 2022

Oncology News and Research

Further Reading

Clinically relevant biomarker strategies in drug development

At-home saliva test to diagnose adrenal insufficiency makes a difference to patients' health

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

Postoperative restrictive opioid protocols reduce long-term opioid use

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

PhoreMost and Boehringer Ingelheim enter multi-project drug discovery collaboration

Study shows the potential of a game-changing drug to treat upper urinary tract urothelial cancers

Precise 3D imaging can help measure radiation during cancer treatment

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Researchers identify novel gene mechanism in most aggressive kidney cancers

New method records gene activity patterns and presence of proteins across tissues

UKB resident awarded the C. E. Alken Prize for outstanding scientific uro-oncological research

Delaying antibiotic treatment does not reduce survival chances in cancer patients with neutropenic fever

Predictive models using serum miRNAs may offer objective criteria for referral to early palliative care services

Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

NCI-led clinical trial results in the first approval of a treatment for advanced alveolar soft part sarcoma

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Researchers discover a protein linked with the onset of anthracycline-associated cardiac toxicity

Cell-based method can predict how breast cancer patients will respond to treatments

eBook: Liquid biopsy in cancer research eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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