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Anti-SARS-CoV-2 / COVID-19 antibody: In stock and new formats

In mid-March, we announced the availability of an anti-coronavirus antibody shown to recognize SARS-CoV-2 (also referred to as 2019-nCoV or COVID-19). The anti-SARS clone, CR3022, was first described in 2006, and in early 2020, researchers showed the clone has high affinity for the then-termed 2019-nCoV. Scientists worldwide are now exploring this antibody as a candidate for mono- as well as combination-therapy development.

From Absolute Antibody Ltd 23 Apr 2020

Study: Somatostatin treatment in cerebral cortex may improve visual processing, cognitive behaviors

Researchers have confirmed that neuropeptide somatostatin can improve cognitive function in the brain. A research group of Professor Seung-Hee Lee from the Department of Biological Sciences at KAIST found that the application of neuropeptide somatostatin improves visual processing and cognitive behaviors by reducing excitatory inputs to parvalbumin-positive interneurons in the cortex.

23 Apr 2020

Chinese scientists develop two novel compounds that inhibit SARS-CoV-2 main protease

A team of Chinese scientists has recently developed two novel compounds that inhibit the SARS-CoV-2 main protease (Mpro) and one of them is a good drug candidate for further clinical studies.

23 Apr 2020

Accelerating Antibody Discovery with Next-Generation Single-Cell Analysis

Accelerating antibody discovery using picodroplet technology for single cell analysis to condense discovery times down to 1-2 days.

From Fluidic Sciences and Sphere Bio 22 Apr 2020

Researchers develop new 3D multicomponent dissolvable vaccine platform

In parallel to their current work on a potential coronavirus vaccine, researchers at the University of Pittsburgh School of Medicine have developed a new vaccine delivery system for vaccines using live or attenuated viral vectors: a finger-tip sized patch that contains 400 tiny needles, each just half of one millimeter.

21 Apr 2020

New study raises red flags about strategy to block cancer drug resistance

Sooner or later, most cancer patients develop resistance to the very chemotherapy drugs designed to kill their cancer, forcing oncologists to seek alternatives.

17 Apr 2020

New cyclic peptide enhances blood-brain barrier penetration

A Japanese research team has developed a cyclic peptide (a chain of amino acids bonded circularly) that enhances blood-brain barrier penetration.

17 Apr 2020

Novel FIMP protein may help orchestrate mammalian fertilization

Fertilization is a fundamental process in sexual reproduction when the combination of male and female gametes blends genetic material to create a new unique individual. Now, researchers from Japan have identified a new factor that may help orchestrate this vitally complex life event.

16 Apr 2020

Real-time imaging reveals how infiltrating glioma cells alter brain function, blood flow

The first sign of trouble for a patient with a growing brain tumor is often a seizure. Such seizures have long been considered a side effect of the tumor.

15 Apr 2020

Study highlights triptolide as valuable therapeutic approach for IDH1-mutated glioma

Findings of a new study led by Prof. XU Guowang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences and Prof. YANG Chunzhang from the National Cancer Institute shed light on the selective therapeutics for IDH1-mutated glioma by targeting glutathione synthesis pathway.

13 Apr 2020

Chemists identify a drug to rescue winter depression-like behavior

A group of animal biologists and chemists at the Institute of Transformative Bio-Molecules, Nagoya University, has used a chemical genomics approach to explore the underlying mechanism of winter depression-like behavior and identified a drug that rescues winter depression-like behavior in medaka fish.

13 Apr 2020

Drinking green tea may benefit people with food allergies

Research findings suggest gut microbes can effect allergic immune responses. Tasuku Ogita who has recently joined Shinshu University is an expert on teas and their effects on gut bacteria.

8 Apr 2020

Pittsburgh professor receives CAREER award to improve clinical applications of brain-computer interfaces

Using electrodes smaller than a human hair, researchers are able to connect mind to machine and interact with the human brain in revolutionary ways.

8 Apr 2020

Experimental drug APN01 prevents COVID-19 infection in the lab

With the world gripped with the COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is a frantic rush to find an effective drug that can be used to treat the disease.

6 Apr 2020

Excess cardiac myosin worsens damage to heart tissue during a heart attack

A prevalent heart protein known as cardiac myosin, which is released into the body when a person suffers a heart attack, can cause blood to thicken or clot--worsening damage to heart tissue, a new study shows.

2 Apr 2020

Total-body PET provides suitable images of antibodies up to 30 days after injection

Combining 89Zr-labeled antibodies with total-body positron emission tomography (PET) has extended the utility of novel total-body PET scanners, providing suitable images up to 30 days after the initial injection.

31 Mar 2020

Horizon Discovery and Pharmahungary report positive early-stage results for novel micro-RNA therapeutic for ischemic heart diseases

Horizon Discovery Group plc and Pharmahungary Group announced positive early-stage results for a novel micro-RNA therapeutic for ischemic heart diseases.