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Cocaine and nicotine employ similar mechanisms to induce synaptic plasticity in brain

The effects of nicotine upon brain regions involved in addiction mirror those of cocaine, according to new neuroscience research.

4 May 2011

Scientists discover new mitochondria regulation mechanism

Scientists have discovered a new component of mitochondria that plays a key part in their function. The discovery, which is presented in the journal Cell Metabolism, is of potential significance to our understanding of both inherited and age-related diseases.

4 May 2011

FDA clears Sectra's digital mammography system

Women in the US will now have the same opportunity as million of European women already have; to undergo mammography with significantly lower radiation dose. This is the result of FDA's clearance of the Swedish IT and medical technology company Sectra's digital mammography system, Sectra MicroDose Mammography.

4 May 2011

FTC, FDA take action on unproven STD drug products

The U.S. Food and Drug Administration and the Federal Trade Commission today announced a joint effort to remove products from the market that make unproven claims to treat, cure, and prevent sexually transmitted diseases.

4 May 2011

Fat-loss leads to earlier death in mice

Since the 1930s scientists have proposed food restriction as a way to extend life in mice. Though feeding a reduced-calorie diet has indeed lengthened the life spans of mice, rats and many other species, new studies with dozens of different mouse strains indicate that food restriction does not work in all cases.

4 May 2011

AHF cautions against fast track FDA-approval for expanded use of Gilead’s Truvada

During its quarterly meeting over the weekend, The Board of Directors of the AIDS Healthcare Foundation (AHF) adopted a resolution cautioning Gilead Sciences against seeking fast track FDA-approval for the expanded use of its best selling AIDS treatment, Truvada, as a possible form of pre-exposure prophylaxis (PrEP) to prevent the transmission of HIV.

4 May 2011

Heart bypass surgery rates fall by 38% between 2001 and 2008: Study

According to latest the U.S. research, the number of heart patients getting bypass surgery fell by 38 percent between 2001 and 2008. This fall reflects several factors, including a decline in smoking rates, which has led to less coronary artery disease, said senior study author Dr. Peter Groeneveld, an assistant professor of medicine at the University of Pennsylvania School of Medicine.

4 May 2011

Herbal remedies commonly used in infants without efficacy & safety guarantees: Study

According to a new U.S. government study parents commonly give infants teas or herbal supplements said to soothe “fussiness” even though there's no good evidence that the products work. The market is flooded with these teas and botanical products with ingredients like chamomile, ginger and fennel that are marketed for easing infants' tummy troubles, fussiness and sleep problems. However there is no evidence that these are effective and safe.

4 May 2011

Confusing research on salt and heart: Study

According to the latest European study, people who ate lots of salt were not more likely to get high blood pressure, and were less likely to die of heart disease than those with a low salt intake. This is contrary to what has been known till date. The U.S. guidelines recommend that Americans consume less than 2,300 milligrams of salt daily - 1,500 mg in certain people who are more at risk for high blood pressure or heart disease.

4 May 2011

New USDA funded, research-based program to combat child obesity

A five-year $4.5 million USDA grant to University of Illinois researchers will establish the Illinois Transdisciplinary Obesity Prevention Program, an innovative research-based program that will combine a Ph.D. with a master's in public health degree focused on child obesity prevention.

4 May 2011

pSivida presents data of ILUVIEN Phase 3 trial in Diabetic Macular Edema at ARVO 2011

pSivida Corp., a leader in developing sustained release, drug delivery products for treatment of back-of-the-eye diseases, today announced the presentation of new data from the completed 36-month FAME Study of ILUVIEN for the treatment of Diabetic Macular Edema at the 2011 ARVO Annual Meeting.

4 May 2011

Cynosure first quarter revenues increase 16% to $21.9 million

Cynosure, Inc. today announced financial results for the three months ended March 31, 2011.

3 May 2011

Nile Therapeutics initiates cenderitide Phase I trial in heart failure

Nile Therapeutics, Inc., a biopharmaceutical company that develops novel therapeutics for heart failure patients, today announced dosing of the first patient in a Phase I clinical trial investigating the use of subcutaneous cenderitide.

3 May 2011

Study: Dual medications do not hasten recovery from depression

Taking two medications for depression does not hasten recovery from the condition that affects 19 million Americans each year, researchers at UT Southwestern Medical Center have found in a national study.

3 May 2011

National survey reveals severe asthmatics need more treatment options

Today on World Asthma Day 2011, despite decades of progress on the management and control of asthma – more research, better understanding and powerful treatments – millions of people with severe asthma are still living with serious, frequent, life-threatening symptoms.

3 May 2011

Calcium and vitamin D intake before bone density test can reduce risk of osteoporosis

Has a bone density scan placed you at risk for osteoporosis, leading your doctor to prescribe a widely advertised bone-building medication? Not so fast! A University of Illinois study finds that an effective first course of action is increasing dietary calcium and vitamin D or taking calcium and vitamin D supplements.

3 May 2011

Tips on how to stay safe and heal emotionally after tornado attack

Although the threat of another tornado is gone for now, other potential dangers lurk in the storm's aftermath, said several University of Alabama at Birmingham experts. They recently offered tips on how to stay safe and heal emotionally in the days after the devastating April 27 storm.

3 May 2011

AHA recommends Omega-3 EPA/DHA intake for individuals with elevated triglyceride levels

The American Heart Association recently issued its first ever statement on triglyceride management that includes recommendations for Omega-3 EPA/DHA intake.

3 May 2011

CTI to re-submit pixantrone NDA to FDA's Office of New Drugs for re-review

Cell Therapeutics, today announced that the Office of New Drugs of the U.S. Food and Drug Administration after carefully reviewing the materials CTI submitted in support of its appeal, the reviews of the New Drug Application for pixantrone prepared by the FDA staff, the transcript of the March 22, 2010 Oncology Drugs Advisory Committee meeting and consulting with the Center for Drug Evaluation and Research's Deputy Director of Clinical Science and the Office of Biostatistics, concluded that accelerated approval of pixantrone NDA 022481 may not necessarily be out of reach based on a single controlled clinical trial, provided two key matters can be satisfactorily resolved.

3 May 2011

Desirudin more effective for VTE prevention in patients with renal impairment

Desirudin reduced major venous thromboembolism and post-operative bleeding compared with the standard of care, enoxaparin, in patients with poor kidney function undergoing orthopedic surgery, according to a poster presented at the Arteriosclerosis, Thrombosis and Vascular Biology meeting.

3 May 2011