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Researchers discover medulloblastoma subtype that responds to less aggressive therapy

The youngest patients with the brain tumor medulloblastoma are among the most challenging because their rapidly developing brains limit treatment options.

17 May 2018

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

Obsidian Therapeutics, Inc., a biotechnology company dedicated to the development of next-generation cell and gene therapies with pharmacologic operating systems, today announced that the company presented preclinical data on its regulated IL12 and IL15 programs at the Annual Meeting of the American Society of Gene and Cell Therapy in Chicago, IL.

17 May 2018

Researchers transplant retinal sheets derived from human embryonic stem cells in retinal degeneration mouse models

Researchers affiliated with the Kawasaki INnovation Gateway at SKYFRONT have developed new mouse models of retinal degeneration that enable transplantation of retinal sheets derived from human embryonic stem cells.

17 May 2018

Scientists disrupt two enzymes to shrink cancer cells

Before cell division, the long strings of the cell's DNA are wrapped tightly into the structures we know as chromosomes. This protects the cell's genetic material from physical and chemical damage.

17 May 2018

New study reveals the extent of brain damage due to elevated homocysteine

The amino acid homocysteine occurs naturally in the human body, generated as a byproduct of methionine metabolism.

17 May 2018

Researchers push science one step closer to growing body parts in a lab

Researchers have learned that precursor cells for skeletal muscles actually also give rise to neurons, blood vessels, blood cells and immune cells, pushing science one step closer to generating body parts in a laboratory.

17 May 2018

Study finds molecular handle that chikungunya virus uses to enter into cells and cause arthritis

Chikungunya virus is a growing threat to the United States and other regions of the world as the mosquito that carries the virus expands its reach. Telltale symptoms of chikungunya infection are fever and joint pain that last about a week.

17 May 2018

Bacterial signals are crucial to development of pre-leukemic myeloproliferation, study shows

A new study by researchers from the University of Chicago Medicine shows that bacterial signals are crucial to the development of a precursor condition to leukemia, which can be induced by disrupting the intestinal barrier or by introducing a bacterial infection.

17 May 2018

Lowering blood cholesterol levels could enhance success of T-cell cancer immunotherapy

Cleveland Clinic researchers have demonstrated for the first time that lowering blood cholesterol levels could enhance the success of a specific type of T-cell immunotherapy in fighting cancer.

16 May 2018

FDA allows KU Medical Center to begin clinical trial of novel cellular therapy for HR/SR aGvHD

The University of Kansas Medical Center announced that the U.S. Food and Drug Administration has cleared it to begin a first-in-human clinical trial of MSCTC-0010 in patients with de novo high-risk acute or steroid-refractory acute graft-versus-host disease (HR/SR aGvHD).

16 May 2018

Combination therapies targeting different cell types may be effective at treating colon cancer

Researchers in Germany have discovered that colon cancers are often resistant to existing drug treatments because they are composed of two different cell types that can replace each other when one cell type is killed.

16 May 2018

Study uncovers mechanism underlying brain malformation linked to severe epilepsy

One of the most frequent causes of drug-resistant epilepsy, considered a difficult disease to control, is a brain malformation known as focal cortical dysplasia.

16 May 2018

FDA clears Turnstone Biologics' IND for immunotherapy targeting HPV positive solid tumors

Turnstone Biologics today announced it has received U.S. Food and Drug Administration clearance of its Investigational New Drug Application for MG1-HPV for the treatment of patients with human papillomavirus positive solid tumors.

16 May 2018

Research offers clues to how random gene fluctuations may be tamed during earliest stages of life

Scientists exploring how to tame random gene fluctuations as the embryos that become our bodies start to form have identified a control switch in the vertebrate segmentation clock of developing zebrafish.

16 May 2018

New study could have important implications for cellular aging

Researchers have found a way to stimulate autophagy, a process used by cells to convert misfolded proteins and redundant organelles into components that the cell can re-use.

16 May 2018

HKBU researchers develop metal based probes for imaging dopamine receptors in living cells

A team led by Dr Edmond Ma Dik-lung, Associate Professor of the Department of Chemistry of Hong Kong Baptist University has developed the world's first iridium(III)-based probes for imaging dopamine receptors in living cells.

16 May 2018

Study illuminates how neuronal activity leads to gene activation

From burning your palm on a hot pan handle to memorizing the name of a new acquaintance, "anytime you experience something, your neurons are active," says Kelsey Tyssowski, a graduate student in genetics at Harvard Medical School.

16 May 2018

Researchers demonstrate new strategy for stimulating autophagy

Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts.

16 May 2018

Study finds distinct exhausted T cells that could have implications for fighting different diseases

The battle between the human immune system and long-term, persisting infections and other chronic diseases such as cancer results in a prolonged stalemate

16 May 2018

Biologists determine how transcription factors function differently in embryonic development

A team of biologists has determined how transcription factors (TFs), which guide gene regulation, function differently in embryonic development.

16 May 2018

B Cell News and Research

Researchers discover medulloblastoma subtype that responds to less aggressive therapy

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

Researchers transplant retinal sheets derived from human embryonic stem cells in retinal degeneration mouse models

Scientists disrupt two enzymes to shrink cancer cells

New study reveals the extent of brain damage due to elevated homocysteine

Researchers push science one step closer to growing body parts in a lab

Study finds molecular handle that chikungunya virus uses to enter into cells and cause arthritis

Bacterial signals are crucial to development of pre-leukemic myeloproliferation, study shows

Lowering blood cholesterol levels could enhance success of T-cell cancer immunotherapy

FDA allows KU Medical Center to begin clinical trial of novel cellular therapy for HR/SR aGvHD

Combination therapies targeting different cell types may be effective at treating colon cancer

Study uncovers mechanism underlying brain malformation linked to severe epilepsy

FDA clears Turnstone Biologics' IND for immunotherapy targeting HPV positive solid tumors

Research offers clues to how random gene fluctuations may be tamed during earliest stages of life

New study could have important implications for cellular aging

HKBU researchers develop metal based probes for imaging dopamine receptors in living cells

Study illuminates how neuronal activity leads to gene activation

Researchers demonstrate new strategy for stimulating autophagy

Study finds distinct exhausted T cells that could have implications for fighting different diseases

Biologists determine how transcription factors function differently in embryonic development

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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