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Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

10 Nov 2025

Routine liquid biopsy testing could reduce late-stage cancer diagnoses

Routine screening is limited to only a few cancer types. New research indicates that routine liquid biopsy testing (multi-cancer early detection testing) could substantially reduce late-stage cancer diagnoses, allowing patients to receive treatment at earlier cancer stages, which are more likely to respond to interventions.

10 Nov 2025

New diagnostic approach identifies dementia stages based on neurovascular and metabolic changes

Researchers from the Indiana University School of Medicine have developed a highly sensitive diagnostic that predicts a person's stage of dementia based on neurovascular and metabolic changes.

10 Nov 2025

Study links dysautonomia to breathing problems in chronic fatigue patients

Chronic fatigue syndrome leaves patients exhausted and struggling with brain fog - and it typically gets worse after mental or physical exercise, a phenomenon called post-exertional malaise.

10 Nov 2025

Exploring cost-effective approaches to detecting familial hypercholesterolemia in children

In the United States, one in every 250 people has inherited a genetic variant that leads to dangerously high cholesterol levels from birth.

10 Nov 2025

Complete revascularization reduces the risk of death from cardiovascular causes

Opening all blocked arteries with stents in patients with a heart attack, known as complete revascularization, reduces the risk of death from cardiovascular causes, death from any cause and future heart attacks compared with opening only culprit artery causing the heart attack according to a new, large international study led by researchers at the Population Health Research Institute (PHRI), a joint organization of McMaster University and Hamilton Health Sciences.

10 Nov 2025

Tailored vitamin D3 supplementation lowers risk of heart attack recurrence

A tailored approach of vitamin D3 supplementation in patients who have suffered a heart attack significantly reduces their risk of a second heart attack, a new study from heart researchers at Intermountain Health in Salt Lake City finds.

10 Nov 2025

Drinking coffee can protect against atrial fibrillation

Drinking coffee can protect against atrial fibrillation (A-Fib), a common heart rhythm disorder that causes rapid, irregular heartbeat and can lead to stroke and heart failure.

10 Nov 2025

Coronary artery calcium score could help predict overall health and all-cause mortality

In a new study of more than 40,000 patients, researchers at Intermountain Health in Salt Lake City have found that patients who have no evidence of calcium in their coronary arteries are not only significantly less likely to die from heart conditions – including heart attacks and heart failure– but also are at reduced risk of death from non-cardiac medical conditions.

10 Nov 2025

Triglyceride-lowering drug can also decrease the risk of acute pancreatitis

Researchers from Mass General Brigham have found that olezarsen-a drug designed to lower triglyceride levels-can also decrease the risk of acute pancreatitis, a potential complication in patients with severely elevated triglyceride levels.

10 Nov 2025

Maternal type 1 diabetes may protect children from developing the disease

Findings suggest maternal T1D exposure leads to protective epigenetic alterations in children, influencing immune response and type 1 diabetes susceptibility.

10 Nov 2025

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Regular orange juice consumption reprograms immune-cell gene activity linked to blood pressure, lipid metabolism, and inflammation in healthy adults. The molecular effects differ by body weight, suggesting BMI-tailored benefits from this everyday beverage.

9 Nov 2025

Using estimated risks and preferences to justify intensive BP control in CKD patients

An analysis of the Systolic Blood Pressure Intervention Trial (SPRINT) indicates that nearly all adults with chronic kidney disease (CKD) would have benefits that outweigh the harm from a systolic blood pressure target of <120 mm Hg compared with a target of <140 mm Hg. The findings will be presented at ASN Kidney Week 2025 November 5– 9.

8 Nov 2025

Preclinical evidence supports sotagliflozin's superior efficacy in attenuating salt-induced kidney damage

Sodium-glucose co-transporter 2 (SGLT2) inhibitors, initially developed to treat type 2 diabetes, have significant heart- and kidney- protective effects. In the kidney, SGLT2 reabsorbs approximately 97% offiltered glucose in the S1 and S2 segments of the proximal tubule, while SGLT1reabsorbs the remainder in the S3 segment.

8 Nov 2025

Investigating the impact of starting HIV drugs within days of infection

Despite effective HIV medication, the immune system of people with HIV remains disrupted in the long term. Researchers at Amsterdam UMC investigated whether this dysregulation can be prevented by starting HIV medication immediately after infection – i.e., within a few days.

8 Nov 2025

Study shows record surge in reduced kidney function worldwide

Record numbers of men and women globally are now estimated to have reduced kidney function, a new study shows. Figures rose from 378 million people with the disease in 1990 to 788 million in 2023 as the world population grew and aged, making it for the first time a top 10 cause of death worldwide.

8 Nov 2025

New study reveals CKD affects nearly 800 million adults worldwide

The number of adults living with chronic kidney disease (CKD) has more than doubled since 1990, reaching nearly 800 million worldwide, according to new research published in The Lancet. The findings come from the Global Burden of Disease (GBD) 2023 study, which tracked CKD trends among adults age 20 years and older across 204 countries and territories from 1990 through 2023.

7 Nov 2025