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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Researchers devise novel technique for crafting human artificial chromosomes

Human artificial chromosomes (HACs) capable of working within human cells could power advanced gene therapies, including those addressing some cancers, along with many laboratory applications, though serious technical obstacles have hindered their development.

21 Mar 2024

Groundbreaking atlas maps over 80 blood stem cell types

Thanks to an unusual application of game theory and machine learning technology, a large team of scientists led by experts at Cincinnati Children's has published the world's most detailed "atlas" of the many types of stem cells and early progenitors involved in producing human blood from diverse donors.

21 Mar 2024

Smoking linked to increased abdominal fat

The worry of gaining weight is a common excuse for smokers not to quit.

21 Mar 2024

Researchers design new bioinformatics tool to identify chromosomal alterations in cancer cells

A team of the University of Barcelona and the Biomedical Research Institute of Barcelona (IRB Barcelona) has designed a new bioinformatics tool to identify the chromosomal alterations that are characteristic of cancer cells.

21 Mar 2024

Using whole genome sequencing to identify non-culturable Legionella

Legionnaires' disease (LD), a rare and severe type of pneumonia, is a respiratory infection caused by species of Legionella bacteria.

21 Mar 2024

Weill Cornell Medicine receives $1.65 million grant for groundbreaking RNA research

A team led by Dr. Samie Jaffrey, the Greenberg-Starr Professor of Pharmacology at Weill Cornell Medicine, has been awarded a three-year, $1.65 million grant for RNA research under a biotechnology-development program run by the U.S. National Science Foundation.

21 Mar 2024

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer's and other diseases.

21 Mar 2024

Bioengineering edible mycelium to enhance nutritional value, color, and flavor

A modular synthetic biology toolkit for Aspergillus oryzae, an edible fungus used in fermented foods.

21 Mar 2024

Middle age: A critical turning point for brain health and cognition

Review emphasizes the significance of midlife for cognitive trajectories and brain health, advocating for research models that capture non-linear changes to better understand the unique processes occurring during this period.

20 Mar 2024

Enhancing the safety and efficacy of breast and ovarian cancer treatment

Some anti-cancer treatments not only target tumour cells but also healthy cells. If their effects on the latter are too strong, their use can become limiting.

20 Mar 2024

Tailored diet could boost growth in malnourished kids via gut bacteria action

Study demonstrates how microbiota-targeted food (MDCF-2) and the presence of Prevotella copri in the gut can enhance weight gain in malnourished children, offering a novel approach to treating malnutrition through diet and microbiome manipulation.

20 Mar 2024

Hearing loss linked to accelerated Alzheimer's progression via GDF1 pathway

Study unveils the GDF1 signaling pathway's role in mitigating the adverse effects of hearing loss on Alzheimer's disease, spotlighting potential avenues for therapeutic development.

20 Mar 2024

Researchers develop a cost-effective method to spatially characterize and map brain epigenomes

An estimated one in six people suffer from a brain disorder worldwide, according to the American Brain Foundation.

20 Mar 2024

Immune cell protein identified as potential target for rare liver cancer treatment

Fibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The disease is caused by a single genetic mutation that creates a fusion protein.

20 Mar 2024

E-cigarette users experience similar DNA changes to specific cheek cells as smokers

E-cigarette users with a limited smoking history experience similar DNA changes to specific cheek cells as smokers, finds a new study led by researchers at UCL (University College London) and University of Innsbruck.

20 Mar 2024

Tracking circulating tumor DNA could indicate gastroesophageal cancer treatment response

Monitoring levels of DNA shed by tumors and circulating in the bloodstream could help doctors accurately assess how gastroesophageal cancers are responding to treatment, and potentially predict future prognosis, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

19 Mar 2024

Understanding schizophrenia through genetics and neural pathways

Our understanding of schizophrenia has increased greatly in recent years, as studies of large groups of people have identified a multitude of genetic variants that increase a person's risk of the disease.

19 Mar 2024

CRISPR-based diagnostics for rapid oral pathogen detection

A study aiming to develop a low-cost, rapid detection technique for the widescale detection and screening of oral microorganisms suitable for point-of-care settings was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.

19 Mar 2024

Study uncovers how APOBEC enzymes drive cancer mutations

A research team led by the University of California, Irvine has discovered the key role that the APOBEC3A and APOBEC3B enzymes play in driving cancer mutations by modifying the DNA in tumor genomes, offering potential new targets for intervention strategies.

18 Mar 2024

Research unveils a cellular shield against harmful effects of UV-induced RNA damage

UV radiation in the sunlight causes sunburn and increases the risk of skin cancer by damaging our DNA but also our RNA.

18 Mar 2024

DNA News and Research

Further Reading

Researchers devise novel technique for crafting human artificial chromosomes

Groundbreaking atlas maps over 80 blood stem cell types

Smoking linked to increased abdominal fat

Researchers design new bioinformatics tool to identify chromosomal alterations in cancer cells

Using whole genome sequencing to identify non-culturable Legionella

Weill Cornell Medicine receives $1.65 million grant for groundbreaking RNA research

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

Bioengineering edible mycelium to enhance nutritional value, color, and flavor

Middle age: A critical turning point for brain health and cognition

Enhancing the safety and efficacy of breast and ovarian cancer treatment

Tailored diet could boost growth in malnourished kids via gut bacteria action

Hearing loss linked to accelerated Alzheimer's progression via GDF1 pathway

Researchers develop a cost-effective method to spatially characterize and map brain epigenomes

Immune cell protein identified as potential target for rare liver cancer treatment

E-cigarette users experience similar DNA changes to specific cheek cells as smokers

Tracking circulating tumor DNA could indicate gastroesophageal cancer treatment response

Understanding schizophrenia through genetics and neural pathways

CRISPR-based diagnostics for rapid oral pathogen detection

Study uncovers how APOBEC enzymes drive cancer mutations

Research unveils a cellular shield against harmful effects of UV-induced RNA damage

Understanding the DNA Damage Response in Innate Immunity eBook

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