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Study shows the critical role of time cells in complex behavioral learning

A sense of time is fundamental to how we understand, recall, and interact with the world.

19 Jun 2024

Personalized brain circuit scores define six depression and anxiety biotypes

Researchers used functional magnetic resonance imaging data on brain circuit function to derive interpretable, personalized brain circuit dysfunction scores for patients with anxiety and depression.

19 Jun 2024

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

A genetic treatment targeting the causal NRAS c.181C>A mutation in congenital melanocytic naevus.

19 Jun 2024

Researchers investigate the gene-brain-behavior link in autism using generative machine learning

Researchers used 3D transport-based morphometry to visualize brain changes linked to 16p11.2 CNV, achieving high prediction accuracy and advancing autism precision medicine.

18 Jun 2024

JACC report card reveals the persistent and tragic inequities in cardiovascular care

As we commemorate Juneteenth 2024, JACC, the flagship journal of the American College of Cardiology, has published "Excess Cardiovascular Mortality Among Black Americans 2000-2022: A Report Card," to highlight the persistent and tragic inequities in cardiovascular care and put in human terms the years of life lost to the Black community because of their higher cardiovascular disease death rates.

18 Jun 2024

New research explores maternal influence on brain biomarkers

A new study by investigators from Mass General Brigham suggests that whether a person inherits risk of Alzheimer's disease from their mother or father influences risk of biological changes in the brain that lead to disease. By evaluating 4,400 cognitively unimpaired adults ages 65-85, the team found those with a history of Alzheimer's disease (AD) on either their mother's side or both parents' sides had increased amyloid in their brains. Their results are published in JAMA Neurology.

18 Jun 2024

Researchers develop cutting-edge smart bandages for improved wound healing

Chronic wounds, which include diabetic ulcers, surgical wounds, pressure injuries, and other problems, are deadlier than many people realize.

17 Jun 2024

Stanford study identifies six depression biotypes for personalized treatment

In the not-too-distant future, a screening assessment for depression could include a quick brain scan to identify the best treatment.

17 Jun 2024

INTEGRA Biosciences announces the appointment of a new board member

INTEGRA Biosciences is excited to welcome Line Stigen Raquet as a non-executive board member.

From INTEGRA Biosciences 17 Jun 2024

AI-based liquid biopsy technology promises early detection of cancer recurrence

An artificial intelligence-powered method for detecting tumor DNA in blood has shown unprecedented sensitivity in predicting cancer recurrence, in a study led by researchers at Weill Cornell Medicine, NewYork-Presbyterian, the New York Genome Center (NYGC) and Memorial Sloan Kettering Cancer Center (MSK).

14 Jun 2024

The hidden genetic switches influencing human height and bone health

In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone.

14 Jun 2024

Climate change heat poses lasting brain risks for children, study finds

The impact of temperature exposure on children's mental health and cognition during prenatal and early childhood periods.

14 Jun 2024

Empowering communities: Penn Medicine's annual mammogram event and health fair

Penn Medicine will once again join with community partners and Siemens Healthineers to host a free mammogram clinic and community health fair in June, giving the West Philadelphia and Upper Darby communities convenient access to health screenings right in their neighborhoods.

13 Jun 2024

MIT researchers develop revolutionary system for high-resolution brain imaging

A suite of three innovations by an MIT-based team enables high-resolution, high-throughput imaging of human brain tissue at a full range of scales and mapping connectivity of neurons at single cell resolution.

13 Jun 2024

Revolutionary platform unveils detailed human brain architecture at multiple scales

A new platform enables simultaneous capture of protein expression, cellular morphology, neural projection, and synapse distribution in large-scale human brain tissues at multiple scales, researchers report.

13 Jun 2024

From Discovery Biology to ELRIG Chair: A Conversation with Melanie Leveridge

In this interview, we speak with Melanie Leveridge, Vice President of Discovery Biology at AstraZeneca and Chair of the Board for ELRIG UK, to discuss her extensive career in the pharmaceutical industry, her role in fostering scientific innovation, and her vision for ELRIG's future.

From ELRIG (UK) Ltd. 13 Jun 2024

UCL researchers identify brain mechanisms behind mood bias in bipolar disorder

Momentary shifts in mood, even those lasting just a matter of seconds, profoundly alter the brain's response to pleasurable experiences in people with bipolar disorder, finds a new study by UCL researchers.

12 Jun 2024

Synthetic cell mimics immune response via symmetry breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

Few UK Alzheimer's patients suitable for new disease-modifying drugs, study finds

Few people in the UK with early stage Alzheimer's disease are likely to be suitable for the latest drugs which aim to halt progress of the condition, yet many are nevertheless likely to be referred for these treatments, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

11 Jun 2024