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New compound proves to be potent against more than 300 drug-resistant bacteria

Urinary tract infections are common, yet are increasingly tough to treat because the bacteria that cause them are becoming resistant to many antibiotics.

10 Aug 2022

How ultraprocessed foods affect gut microbiome and health

Researchers describe the association between the consumption of ultraprocessed foods and chronic medical conditions.

10 Aug 2022

Research may lead the way to a simpler treatment for cancer

Sometimes too much of a good thing is not good at all. Inhibiting the function of the PD-1 protein, which blocks immune function, has shown high therapeutic efficacy in cancer immunotherapy.

10 Aug 2022

UTSW scientists discover mechanism of RNA capping by SARS-CoV-2 virus

A team led by UT Southwestern researchers has identified how SARS-CoV-2, the virus that causes COVID-19, builds a structure called the RNA cap that's critical for successful viral replication.

10 Aug 2022

Scientists explore ecological firewalls for the containment of synthetic microbes

In a new study, researchers described ecological firewalls (EFWs) to contain synthetic microbes.

10 Aug 2022

Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

Melanopsin (OPN4) is a light-sensing protein found in skin and retina cells. A new study conducted at the University of São Paulo (USP) in Brazil suggests that OPN4 can also participate in the development and progression of melanoma, the most aggressive type of skin cancer.

10 Aug 2022

Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes, which are commonly used to build drug molecules.

9 Aug 2022

MIT researchers develop an easy-to-use test to predict Covid-19 immunity

Most people in the United States have some degree of immune protection against Covid-19, either from vaccination, infection, or a combination of the two. But, just how much protection does any individual person have?

9 Aug 2022

Research reveals a gut-brain pathway that contributes to the development of Alzheimer’s disease

Research led by Drs. Yuhai Zhao and Walter J Lukiw at the LSU Health New Orleans Neuroscience Center and the Departments of Cell Biology and Anatomy, Neurology and Ophthalmology, reports for the first time a pathway that begins in the gut and ends with a potent pro-inflammatory toxin in brain cells contributing to the development of Alzheimer's disease (AD).

9 Aug 2022

Research paves the way for therapies to treat or delay preterm labor

Researchers have identified a cause of preterm labor, an enigma that has long challenged researchers. New research published in The Journal of Physiology suggests a protein, called Piezo1, is responsible for regulating the behavior of the uterus.

9 Aug 2022

Researchers develop a potential way to tackle one of the underlying causes of asthma

A possible way to tackle one of the underlying causes of asthma has been developed by researchers from Aston University and Imperial College London.

9 Aug 2022

Novel AI tools accurately predict the role of DNA’s regulatory elements

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies in Nature Genetics.

9 Aug 2022

Researchers unravel a novel molecular target of eicosapentaenoic acid

Eicosapentaenoic acid (EPA) is an essential nutrient belonging to the omega-3 group of polyunsaturated fatty acids (PUFAs). As the human body cannot synthesize PUFAs, dietary supplements containing EPA are required for normal physiological functions. Found abundantly in natural sources like fish, hemp oil, and linseed oil, EPA is known to exhibit anti-inflammatory, neuroprotective, and cardiovascular protective activities.

9 Aug 2022

Researchers synthesize a small molecule that can be used to treat a range of cancers

Researchers at Tel Aviv University and the University of Lisbon have jointly identified and synthesized a small molecule that could be a more accessible and effective alternative to an antibody that is successfully used to treat a range of cancers.

8 Aug 2022

Researchers unravel the mechanism of teixobactin at the atomic level

Researchers explored the mechanisms underlying the bactericidal action of teixobactin at an atomic level.

8 Aug 2022

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Researchers examined the impact of tau neuropathology of APOE3 Christchurch (APOE3ch) homozygote against Alzheimer’s disease.

8 Aug 2022

Researchers create a physical wiring diagram of the human immune system

In a new study, researchers systematically mapped the surface proteins on human leukocytes to examine interactions between their cell-surface proteomes and develop a physical wiring diagram encapsulating the diversity of surface protein architectures found across all major subsets of leukocytes.

8 Aug 2022

Research suggests a new nanomedicine strategy for treatment of IBD patients

Inflammatory bowel disease (IBD), also known as "green cancer", is a chronic, non-specific disease of the intestine. IBD includes ulcerative colitis and Crohn's disease, both of which tend to be debilitating, lifelong conditions that can prove fatal in severe cases. Currently, there is no cure for IBD. The main clinical treatments are drugs such as aminosalicylic acid preparations and corticosteroids, but they are often accompanied by gastrointestinal problems, anemia, and various intestinal complications. Finding alternative, more effective options is a priority for researchers.

5 Aug 2022

Researchers delve deeper into the structure of protein receptor crucial for cardiovascular health

5 Aug 2022

New method can modify an entire substance class of medically relevant natural products

The use of the element fluorine to modify active substances is an important tool in modern drug development.

5 Aug 2022

Molecule News and Research

New compound proves to be potent against more than 300 drug-resistant bacteria

How ultraprocessed foods affect gut microbiome and health

Research may lead the way to a simpler treatment for cancer

UTSW scientists discover mechanism of RNA capping by SARS-CoV-2 virus

Scientists explore ecological firewalls for the containment of synthetic microbes

Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

MIT researchers develop an easy-to-use test to predict Covid-19 immunity

Research reveals a gut-brain pathway that contributes to the development of Alzheimer’s disease

Research paves the way for therapies to treat or delay preterm labor

Researchers develop a potential way to tackle one of the underlying causes of asthma

Novel AI tools accurately predict the role of DNA’s regulatory elements

Researchers unravel a novel molecular target of eicosapentaenoic acid

Researchers synthesize a small molecule that can be used to treat a range of cancers

Researchers unravel the mechanism of teixobactin at the atomic level

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Researchers create a physical wiring diagram of the human immune system

Research suggests a new nanomedicine strategy for treatment of IBD patients

Researchers delve deeper into the structure of protein receptor crucial for cardiovascular health

New method can modify an entire substance class of medically relevant natural products

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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